DE10000311A1 - Aminomethyl-Phonyl-Cyclohexanonderivate - Google Patents

Aminomethyl-Phonyl-Cyclohexanonderivate

Info

Publication number
DE10000311A1
DE10000311A1 DE10000311A DE10000311A DE10000311A1 DE 10000311 A1 DE10000311 A1 DE 10000311A1 DE 10000311 A DE10000311 A DE 10000311A DE 10000311 A DE10000311 A DE 10000311A DE 10000311 A1 DE10000311 A1 DE 10000311A1
Authority
DE
Germany
Prior art keywords
unsubstituted
polysubstituted
mono
alkyl
unbranched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10000311A
Other languages
German (de)
English (en)
Inventor
Claudia Puetz
Helmut Buschmann
Babette-Yvonne Koegel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grünenthal GmbH
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Priority to DE10000311A priority Critical patent/DE10000311A1/de
Priority to AU30169/01A priority patent/AU782862B2/en
Priority to HU0203859A priority patent/HUP0203859A3/hu
Priority to DK00990824T priority patent/DK1246791T3/da
Priority to SI200030587T priority patent/SI1246791T1/xx
Priority to CA002396310A priority patent/CA2396310A1/en
Priority to KR1020027008706A priority patent/KR100748378B1/ko
Priority to BR0016941-2A priority patent/BR0016941A/pt
Priority to IL15055800A priority patent/IL150558A0/xx
Priority to RU2002120897/04A priority patent/RU2002120897A/ru
Priority to MXPA02006697A priority patent/MXPA02006697A/es
Priority to PCT/EP2000/013282 priority patent/WO2001049651A2/de
Priority to NZ520468A priority patent/NZ520468A/en
Priority to SK980-2002A priority patent/SK286799B6/sk
Priority to JP2001550191A priority patent/JP2003519209A/ja
Priority to ES00990824T priority patent/ES2231304T3/es
Priority to AT00990824T priority patent/ATE280752T1/de
Priority to DE50008447T priority patent/DE50008447D1/de
Priority to PT00990824T priority patent/PT1246791E/pt
Priority to CNB008192669A priority patent/CN100467441C/zh
Priority to EP20000990824 priority patent/EP1246791B1/de
Priority to CZ20022338A priority patent/CZ20022338A3/cs
Priority to PL00356642A priority patent/PL356642A1/xx
Priority to HK03102442.7A priority patent/HK1050890B/xx
Priority to ARP010100008A priority patent/AR030683A1/es
Priority to PE2001000012A priority patent/PE20011043A1/es
Priority to CO01000529A priority patent/CO5261627A1/es
Publication of DE10000311A1 publication Critical patent/DE10000311A1/de
Priority to NO20022983A priority patent/NO20022983L/no
Priority to IL150558A priority patent/IL150558A/en
Priority to US10/189,184 priority patent/US6890959B2/en
Priority to ZA200206150A priority patent/ZA200206150B/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE10000311A 2000-01-05 2000-01-05 Aminomethyl-Phonyl-Cyclohexanonderivate Withdrawn DE10000311A1 (de)

Priority Applications (31)

Application Number Priority Date Filing Date Title
DE10000311A DE10000311A1 (de) 2000-01-05 2000-01-05 Aminomethyl-Phonyl-Cyclohexanonderivate
AT00990824T ATE280752T1 (de) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate
ES00990824T ES2231304T3 (es) 2000-01-05 2000-12-27 Derivados de aminometil fenil ciclohexanona.
DK00990824T DK1246791T3 (da) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyklohexanonderivater
SI200030587T SI1246791T1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
CA002396310A CA2396310A1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
KR1020027008706A KR100748378B1 (ko) 2000-01-05 2000-12-27 아미노메틸-페닐-사이클로헥사논 유도체
BR0016941-2A BR0016941A (pt) 2000-01-05 2000-12-27 Derivados de aminometil-fenil-ciclohexanona
IL15055800A IL150558A0 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
DE50008447T DE50008447D1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate
MXPA02006697A MXPA02006697A (es) 2000-01-05 2000-12-27 Derivados de aminometil-fenil-ciclohexanona.
PCT/EP2000/013282 WO2001049651A2 (de) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate
NZ520468A NZ520468A (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
SK980-2002A SK286799B6 (sk) 2000-01-05 2000-12-27 Deriváty aminometyl-fenyl-cyklohexanónu, spôsob ich výroby, liečivá tieto látky obsahujúce a ich použitie
JP2001550191A JP2003519209A (ja) 2000-01-05 2000-12-27 アミノメチル−フェニル−シクロヘキサノン誘導体
AU30169/01A AU782862B2 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
PT00990824T PT1246791E (pt) 2000-01-05 2000-12-27 Derivados de aminometilfenilciclo-hexanona
RU2002120897/04A RU2002120897A (ru) 2000-01-05 2000-12-27 Производные аминометилфенилциклогексанона
HU0203859A HUP0203859A3 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives, process for their preparation, pharmaceutical compositions containing them and their use
CNB008192669A CN100467441C (zh) 2000-01-05 2000-12-27 氨甲基-苯基-环己酮衍生物
EP20000990824 EP1246791B1 (de) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate
CZ20022338A CZ20022338A3 (cs) 2000-01-05 2000-12-27 Deriváty aminomethyl-fenyl-cyklohexanu, způsob jejich výroby, léčiva tyto látky obsahující a jejich pouľití
PL00356642A PL356642A1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
HK03102442.7A HK1050890B (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanone derivatives
ARP010100008A AR030683A1 (es) 2000-01-05 2001-01-02 Derivados de aminometil-fenil-ciclohexanona, procedimiento para su preparacion, el uso de los derivados de aminometil-fenil-ciclohexanona para la preparacion de medicamentos y medicamentos que contienen los derivados de aminometil-fenil-ciclohexanona
PE2001000012A PE20011043A1 (es) 2000-01-05 2001-01-04 Derivados de aminometil-fenil-ciclohexanona, procedimiento para su preparacion y medicamentos que los contienen
CO01000529A CO5261627A1 (es) 2000-01-05 2001-01-04 Derivados de aminometil-fenil-ciclohexanona, procedimiento para su preparacion, el uso de los derivados de aminometil- fenil-ciclohexanona para la preparacion de medicamentos y medicamentos que contienen los derivados de aminometil- fenil-ciclohexano
NO20022983A NO20022983L (no) 2000-01-05 2002-06-20 Aminometyl-fenyl-cykloheksanonderivater
IL150558A IL150558A (en) 2000-01-05 2002-07-03 History of Aminomethyl-Phenyl-Cyclo-Cyclone
US10/189,184 US6890959B2 (en) 2000-01-05 2002-07-05 Aminomethyl-phenyl-cyclohexanone derivatives
ZA200206150A ZA200206150B (en) 2000-01-05 2002-08-01 Aminomethyl-phenyl-cyclohexanone derivatives.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10000311A DE10000311A1 (de) 2000-01-05 2000-01-05 Aminomethyl-Phonyl-Cyclohexanonderivate

Publications (1)

Publication Number Publication Date
DE10000311A1 true DE10000311A1 (de) 2001-07-12

Family

ID=7626852

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10000311A Withdrawn DE10000311A1 (de) 2000-01-05 2000-01-05 Aminomethyl-Phonyl-Cyclohexanonderivate
DE50008447T Expired - Lifetime DE50008447D1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50008447T Expired - Lifetime DE50008447D1 (en) 2000-01-05 2000-12-27 Aminomethyl-phenyl-cyclohexanonderivate

Country Status (28)

Country Link
US (1) US6890959B2 (enExample)
EP (1) EP1246791B1 (enExample)
JP (1) JP2003519209A (enExample)
KR (1) KR100748378B1 (enExample)
CN (1) CN100467441C (enExample)
AR (1) AR030683A1 (enExample)
AT (1) ATE280752T1 (enExample)
AU (1) AU782862B2 (enExample)
BR (1) BR0016941A (enExample)
CA (1) CA2396310A1 (enExample)
CO (1) CO5261627A1 (enExample)
CZ (1) CZ20022338A3 (enExample)
DE (2) DE10000311A1 (enExample)
DK (1) DK1246791T3 (enExample)
ES (1) ES2231304T3 (enExample)
HU (1) HUP0203859A3 (enExample)
IL (2) IL150558A0 (enExample)
MX (1) MXPA02006697A (enExample)
NO (1) NO20022983L (enExample)
NZ (1) NZ520468A (enExample)
PE (1) PE20011043A1 (enExample)
PL (1) PL356642A1 (enExample)
PT (1) PT1246791E (enExample)
RU (1) RU2002120897A (enExample)
SI (1) SI1246791T1 (enExample)
SK (1) SK286799B6 (enExample)
WO (1) WO2001049651A2 (enExample)
ZA (1) ZA200206150B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7457762B2 (en) * 2001-09-04 2008-11-25 Accenture Global Services Gmbh Optimization of management of maintenance, repair and overhaul of equipment in a specified time window
DE10326097A1 (de) * 2003-06-06 2005-01-05 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen
DE10328316A1 (de) 2003-06-23 2005-01-20 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe
US7260408B2 (en) * 2004-02-20 2007-08-21 Airespace, Inc. Wireless node location mechanism using antenna pattern diversity to enhance accuracy of location estimates
US20050236892A1 (en) * 2004-04-27 2005-10-27 Akihito Kusano Hydraulic braking pressure generating apparatus for vehicles
DE102005052588A1 (de) 2005-11-02 2007-05-10 Grünenthal GmbH Verfahren zur Herstellung substituierter Dimethyl-(3-aryl-butyl)-amin-Verbindungen mittels homogener Katalyse
TWI496762B (zh) 2006-07-24 2015-08-21 歌林達股份有限公司 製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法
JP5009736B2 (ja) * 2007-10-15 2012-08-22 日本曹達株式会社 環状アミノエーテルを用いたマンニッヒ反応
US7763754B2 (en) 2008-02-29 2010-07-27 Gruenenthal Gmbh Process for producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3564100A (en) * 1965-08-02 1971-02-16 Gruenenthal Chemie Basically substituted cycloalkene compounds as antitussive agents
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
DE19525137A1 (de) * 1995-07-11 1997-01-16 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen als pharmazeutische Wirkstoffe
DE19547766A1 (de) * 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974157A (en) * 1974-03-04 1976-08-10 Pennwalt Corporation 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters
JPS51143650A (en) * 1975-06-06 1976-12-10 Takeda Chem Ind Ltd A process for preparing cyclohexanol derivatives
IL93610A0 (en) 1989-03-08 1990-12-23 Merck Sharp & Dohme Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL112569A (en) * 1994-02-10 1999-12-22 Wyeth John & Brother Ltd Pharmaceutical compositions comprising cyclohexylamine derivatives certain such novel compounds and their preparation
MY125037A (en) 1998-06-10 2006-07-31 Glaxo Wellcome Spa 1,2,3,4 tetrahydroquinoline derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3564100A (en) * 1965-08-02 1971-02-16 Gruenenthal Chemie Basically substituted cycloalkene compounds as antitussive agents
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
DE19525137A1 (de) * 1995-07-11 1997-01-16 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen als pharmazeutische Wirkstoffe
DE19547766A1 (de) * 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate

Also Published As

Publication number Publication date
EP1246791B1 (de) 2004-10-27
CA2396310A1 (en) 2001-07-12
CN100467441C (zh) 2009-03-11
SK9802002A3 (en) 2003-03-04
PE20011043A1 (es) 2001-11-24
NO20022983D0 (no) 2002-06-20
HK1050890A1 (en) 2003-07-11
PL356642A1 (en) 2004-06-28
AU782862B2 (en) 2005-09-01
AR030683A1 (es) 2003-09-03
HUP0203859A3 (en) 2008-01-28
WO2001049651A3 (de) 2002-05-23
RU2002120897A (ru) 2004-01-10
DE50008447D1 (en) 2004-12-02
CO5261627A1 (es) 2003-03-31
KR20020063296A (ko) 2002-08-01
SI1246791T1 (en) 2005-06-30
ES2231304T3 (es) 2005-05-16
US20030096811A1 (en) 2003-05-22
WO2001049651A2 (de) 2001-07-12
ATE280752T1 (de) 2004-11-15
CZ20022338A3 (cs) 2002-11-13
HUP0203859A2 (hu) 2003-03-28
DK1246791T3 (da) 2005-02-14
NO20022983L (no) 2002-08-28
SK286799B6 (sk) 2009-05-07
EP1246791A2 (de) 2002-10-09
IL150558A0 (en) 2003-02-12
CN1437575A (zh) 2003-08-20
ZA200206150B (en) 2003-11-03
IL150558A (en) 2007-03-08
AU3016901A (en) 2001-07-16
BR0016941A (pt) 2003-02-25
PT1246791E (pt) 2005-03-31
MXPA02006697A (es) 2002-09-30
JP2003519209A (ja) 2003-06-17
KR100748378B1 (ko) 2007-08-10
NZ520468A (en) 2003-11-28
US6890959B2 (en) 2005-05-10

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