DD287040A5 - Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide - Google Patents

Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide Download PDF

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Publication number
DD287040A5
DD287040A5 DD89331251A DD33125189A DD287040A5 DD 287040 A5 DD287040 A5 DD 287040A5 DD 89331251 A DD89331251 A DD 89331251A DD 33125189 A DD33125189 A DD 33125189A DD 287040 A5 DD287040 A5 DD 287040A5
Authority
DD
German Democratic Republic
Prior art keywords
oligonucleotides
substituted
nucleosides
nucleotides
oligonucleotide
Prior art date
Application number
DD89331251A
Other languages
German (de)
English (en)
Inventor
Frank Schubert
Dieter Cech
Kerstin Ahlert
Original Assignee
Veb Forschungszentrum Biotechnologie Berlin,De
Humboldt-Universitaet Zu Berlin,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veb Forschungszentrum Biotechnologie Berlin,De, Humboldt-Universitaet Zu Berlin,De filed Critical Veb Forschungszentrum Biotechnologie Berlin,De
Priority to DD89331251A priority Critical patent/DD287040A5/de
Priority to DE4023212A priority patent/DE4023212A1/de
Publication of DD287040A5 publication Critical patent/DD287040A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/007—Dyestuffs containing phosphonic or phosphinic acid groups and derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
DD89331251A 1989-07-28 1989-07-28 Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide DD287040A5 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DD89331251A DD287040A5 (de) 1989-07-28 1989-07-28 Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide
DE4023212A DE4023212A1 (de) 1989-07-28 1990-07-19 Neue fluorophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD89331251A DD287040A5 (de) 1989-07-28 1989-07-28 Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide

Publications (1)

Publication Number Publication Date
DD287040A5 true DD287040A5 (de) 1991-02-14

Family

ID=5611220

Family Applications (1)

Application Number Title Priority Date Filing Date
DD89331251A DD287040A5 (de) 1989-07-28 1989-07-28 Neue fluophorderivate, verfahren zu ihrer herstellung und deren verwendung zur herstellung neuartiger fluoreszenzmarkierter nucleoside, nucleotide und oligonucleotide

Country Status (2)

Country Link
DD (1) DD287040A5 (ja)
DE (1) DE4023212A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750341A (en) * 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
DE19627032C2 (de) * 1996-07-04 1999-04-15 Deutsches Krebsforsch Verfahren zum Abbau von potentiell veränderten Nukleinsäuren
JP2004508448A (ja) * 2000-09-06 2004-03-18 エボテック・オーアーイー・アーゲー オキサジン誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3642939A1 (de) * 1986-06-03 1987-12-10 Europ Lab Molekularbiolog Verfahren zur dna-markierung

Also Published As

Publication number Publication date
DE4023212A1 (de) 1991-02-07
DE4023212C2 (ja) 1991-11-07

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