DD283380A5 - Verfahren zur herstellung von flourmethoxyphenyl-dihydropyrindine - Google Patents
Verfahren zur herstellung von flourmethoxyphenyl-dihydropyrindine Download PDFInfo
- Publication number
- DD283380A5 DD283380A5 DD88321316A DD32131688A DD283380A5 DD 283380 A5 DD283380 A5 DD 283380A5 DD 88321316 A DD88321316 A DD 88321316A DD 32131688 A DD32131688 A DD 32131688A DD 283380 A5 DD283380 A5 DD 283380A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- carbon atoms
- formula
- optionally
- ester
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873737340 DE3737340A1 (de) | 1987-11-04 | 1987-11-04 | Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD283380A5 true DD283380A5 (de) | 1990-10-10 |
Family
ID=6339713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD88321316A DD283380A5 (de) | 1987-11-04 | 1988-11-01 | Verfahren zur herstellung von flourmethoxyphenyl-dihydropyrindine |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5008279A (zh) |
| EP (1) | EP0315018A3 (zh) |
| JP (1) | JPH01151555A (zh) |
| KR (1) | KR890008097A (zh) |
| CN (1) | CN1040192A (zh) |
| AU (1) | AU613101B2 (zh) |
| DD (1) | DD283380A5 (zh) |
| DE (1) | DE3737340A1 (zh) |
| DK (1) | DK614088A (zh) |
| FI (1) | FI885056A (zh) |
| HU (1) | HU201526B (zh) |
| IL (1) | IL88237A0 (zh) |
| NO (1) | NO884671L (zh) |
| PT (1) | PT88920B (zh) |
| ZA (1) | ZA888234B (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5137889A (en) * | 1983-12-02 | 1992-08-11 | Otsuka Pharmaceutical Co., Ltd. | Dihydropyridine derivatives and process for preparing the same |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| JPH11510479A (ja) | 1995-06-07 | 1999-09-14 | ネオルックス コーポレイション | タモキシフェン類似体による心臓血管疾病の予防及び治療 |
| US6117911A (en) | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| CN1261348A (zh) | 1997-04-25 | 2000-07-26 | 味之素株式会社 | 新型二氢吡啶衍生物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2752820A1 (de) * | 1977-11-26 | 1979-05-31 | Bayer Ag | Neue nitrosubstituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4285955A (en) * | 1978-10-31 | 1981-08-25 | Bayer Aktiengesellschaft | 1,4-Dihydropyridinecarboxylic acids |
| DE3447169A1 (de) * | 1984-12-22 | 1986-07-03 | Bayer Ag, 5090 Leverkusen | Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
| US4868181A (en) * | 1986-08-04 | 1989-09-19 | E. I. Du Pont De Nemours And Company | 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity |
| US4920225A (en) * | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
| DE3737341A1 (de) * | 1987-11-04 | 1989-05-18 | Bayer Ag | Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
| DE3821334A1 (de) * | 1988-06-24 | 1989-12-28 | Bayer Ag | 1,4-dihydropyridin-threonin-derivate, verfahren zu ihrer herstellung, zwischenprodukte und ihre verwendung als arzneimittel |
-
1987
- 1987-11-04 DE DE19873737340 patent/DE3737340A1/de not_active Withdrawn
-
1988
- 1988-10-20 NO NO88884671A patent/NO884671L/no unknown
- 1988-10-25 EP EP88117702A patent/EP0315018A3/de not_active Withdrawn
- 1988-10-27 US US07/263,671 patent/US5008279A/en not_active Expired - Fee Related
- 1988-10-31 IL IL88237A patent/IL88237A0/xx unknown
- 1988-11-01 AU AU24576/88A patent/AU613101B2/en not_active Ceased
- 1988-11-01 DD DD88321316A patent/DD283380A5/de not_active IP Right Cessation
- 1988-11-02 FI FI885056A patent/FI885056A/fi not_active Application Discontinuation
- 1988-11-02 PT PT88920A patent/PT88920B/pt not_active IP Right Cessation
- 1988-11-03 DK DK614088A patent/DK614088A/da not_active Application Discontinuation
- 1988-11-03 KR KR1019880014437A patent/KR890008097A/ko not_active Application Discontinuation
- 1988-11-03 CN CN88107639A patent/CN1040192A/zh active Pending
- 1988-11-03 ZA ZA888234A patent/ZA888234B/xx unknown
- 1988-11-04 HU HU885711A patent/HU201526B/hu not_active IP Right Cessation
- 1988-11-04 JP JP63279182A patent/JPH01151555A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1040192A (zh) | 1990-03-07 |
| JPH01151555A (ja) | 1989-06-14 |
| FI885056A (fi) | 1989-05-05 |
| AU2457688A (en) | 1989-05-04 |
| NO884671L (no) | 1989-05-05 |
| DE3737340A1 (de) | 1989-05-24 |
| PT88920A (pt) | 1988-12-01 |
| IL88237A0 (en) | 1989-06-30 |
| US5008279A (en) | 1991-04-16 |
| ZA888234B (en) | 1989-07-26 |
| PT88920B (pt) | 1993-01-29 |
| HU201526B (en) | 1990-11-28 |
| AU613101B2 (en) | 1991-07-25 |
| DK614088A (da) | 1989-05-05 |
| DK614088D0 (da) | 1988-11-03 |
| HUT48591A (en) | 1989-06-28 |
| EP0315018A2 (de) | 1989-05-10 |
| NO884671D0 (no) | 1988-10-20 |
| KR890008097A (ko) | 1989-11-26 |
| EP0315018A3 (de) | 1990-07-18 |
| FI885056A0 (fi) | 1988-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |