DD244553A5 - Verfahren zur herstellung von 5,6-difluor-naphthyridinen und 5,6,8-trifluorchinolinen - Google Patents

Verfahren zur herstellung von 5,6-difluor-naphthyridinen und 5,6,8-trifluorchinolinen Download PDF

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Publication number
DD244553A5
DD244553A5 DD86289148A DD28914886A DD244553A5 DD 244553 A5 DD244553 A5 DD 244553A5 DD 86289148 A DD86289148 A DD 86289148A DD 28914886 A DD28914886 A DD 28914886A DD 244553 A5 DD244553 A5 DD 244553A5
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DD
German Democratic Republic
Prior art keywords
oxo
dihydro
acid
ethyl
compounds
Prior art date
Application number
DD86289148A
Other languages
German (de)
English (en)
Inventor
Thomas F Mich
Jeffrey B Nichols
John M Domagala
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������`�����@�������k�� filed Critical �������`�����@�������k��
Publication of DD244553A5 publication Critical patent/DD244553A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
DD86289148A 1985-04-18 1986-04-15 Verfahren zur herstellung von 5,6-difluor-naphthyridinen und 5,6,8-trifluorchinolinen DD244553A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/724,442 US4657913A (en) 1985-04-18 1985-04-18 Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents

Publications (1)

Publication Number Publication Date
DD244553A5 true DD244553A5 (de) 1987-04-08

Family

ID=24910460

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86289148A DD244553A5 (de) 1985-04-18 1986-04-15 Verfahren zur herstellung von 5,6-difluor-naphthyridinen und 5,6,8-trifluorchinolinen

Country Status (22)

Country Link
US (1) US4657913A (zh)
EP (1) EP0202763B1 (zh)
JP (1) JPS61243077A (zh)
KR (1) KR890005199B1 (zh)
CN (1) CN1012064B (zh)
AR (1) AR240458A1 (zh)
AT (1) ATE47853T1 (zh)
AU (1) AU587811B2 (zh)
DD (1) DD244553A5 (zh)
DE (1) DE3666820D1 (zh)
DK (1) DK172786A (zh)
ES (1) ES8800160A1 (zh)
FI (1) FI861574A (zh)
GR (1) GR860998B (zh)
HU (1) HU195498B (zh)
IL (1) IL78528A (zh)
NO (1) NO166080C (zh)
NZ (1) NZ215868A (zh)
OA (1) OA08236A (zh)
PH (1) PH23770A (zh)
PT (1) PT82414B (zh)
ZA (1) ZA862388B (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
ATE75740T1 (de) * 1985-06-26 1992-05-15 Daiichi Seiyaku Co Pyridoncarbonsaeurederivate.
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
GB8612137D0 (en) * 1986-05-19 1986-06-25 Fujisawa Pharmaceutical Co Quinolone compounds
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607503B1 (fr) * 1986-12-02 1989-02-24 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
JPH0794452B2 (ja) * 1987-10-16 1995-10-11 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
MY105136A (en) 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
US4992449A (en) * 1990-02-01 1991-02-12 American Cyanamid Company 7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
ID16655A (id) * 1996-04-24 1997-10-30 Daiichi Seiyaku Co Turunan-turunan sikloalkilaminometilpirolidina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963736A (en) * 1970-01-28 1976-06-15 Sumitomo Chemical Company, Limited Preparation of 1-(lower alkyl)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids
US3907808A (en) * 1971-05-17 1975-09-23 Sterling Drug Inc 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
CA1175836A (en) * 1977-09-20 1984-10-09 Marcel Pesson Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
HU188181B (en) * 1981-06-11 1986-03-28 Warner-Lambert Co,Us Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity
US4477449A (en) * 1982-04-19 1984-10-16 Warner-Lambert Company Certain 1,8-naphthyridine compounds useful as antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
AU4042085A (en) * 1985-03-27 1986-10-02 Brugnoli, Angelo Energy system using hydrostatic pressure air compressor

Also Published As

Publication number Publication date
OA08236A (en) 1987-10-30
PH23770A (en) 1989-11-03
DK172786A (da) 1986-10-19
IL78528A (en) 1990-09-17
DK172786D0 (da) 1986-04-16
KR890005199B1 (ko) 1989-12-18
AR240458A1 (es) 1990-04-30
FI861574A (fi) 1986-10-19
CN1012064B (zh) 1991-03-20
ZA862388B (en) 1987-11-25
GR860998B (en) 1986-08-12
NO166080C (no) 1991-05-29
IL78528A0 (en) 1986-08-31
EP0202763A1 (en) 1986-11-26
CN86102683A (zh) 1986-12-03
NO861509L (no) 1986-10-20
ES8800160A1 (es) 1987-10-16
ES554142A0 (es) 1987-10-16
PT82414A (en) 1986-05-01
US4657913A (en) 1987-04-14
HU195498B (en) 1988-05-30
FI861574A0 (fi) 1986-04-14
HUT41020A (en) 1987-03-30
DE3666820D1 (en) 1989-12-14
ATE47853T1 (de) 1989-11-15
EP0202763B1 (en) 1989-11-08
JPS61243077A (ja) 1986-10-29
AU5561586A (en) 1986-10-23
KR860008164A (ko) 1986-11-12
PT82414B (pt) 1988-05-27
NZ215868A (en) 1988-08-30
AU587811B2 (en) 1989-08-31
NO166080B (no) 1991-02-18

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ENJ Ceased due to non-payment of renewal fee