DD201974A5 - Verfahren zur herstellung von festen arzneizubereitungen enthaltend nifedipin - Google Patents
Verfahren zur herstellung von festen arzneizubereitungen enthaltend nifedipin Download PDFInfo
- Publication number
- DD201974A5 DD201974A5 DD81232939A DD23293981A DD201974A5 DD 201974 A5 DD201974 A5 DD 201974A5 DD 81232939 A DD81232939 A DD 81232939A DD 23293981 A DD23293981 A DD 23293981A DD 201974 A5 DD201974 A5 DD 201974A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- nifedipine
- pharmaceutical preparations
- specific surface
- surface area
- preparations containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803033919 DE3033919A1 (de) | 1980-09-09 | 1980-09-09 | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
DD201974A5 true DD201974A5 (de) | 1983-08-24 |
Family
ID=6111496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD81232939A DD201974A5 (de) | 1980-09-09 | 1981-09-01 | Verfahren zur herstellung von festen arzneizubereitungen enthaltend nifedipin |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0047899B2 (fr) |
JP (1) | JPS5914446B2 (fr) |
AR (1) | AR226377A1 (fr) |
AT (1) | ATE5761T1 (fr) |
AU (1) | AU558331B2 (fr) |
CA (1) | CA1180277A (fr) |
DD (1) | DD201974A5 (fr) |
DE (2) | DE3033919A1 (fr) |
DK (1) | DK154326C (fr) |
FI (1) | FI72648B (fr) |
GR (1) | GR78237B (fr) |
HU (1) | HU184879B (fr) |
IE (1) | IE51549B1 (fr) |
IL (1) | IL63749A (fr) |
NO (1) | NO157368B (fr) |
NZ (1) | NZ198285A (fr) |
PH (1) | PH24097A (fr) |
PL (1) | PL232951A1 (fr) |
PT (1) | PT73603B (fr) |
ZA (1) | ZA816213B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5264446A (en) * | 1980-09-09 | 1993-11-23 | Bayer Aktiengesellschaft | Solid medicament formulations containing nifedipine, and processes for their preparation |
JPS5846019A (ja) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | 持続性ニフエジピン製剤 |
DE3222367A1 (de) * | 1982-06-15 | 1983-12-15 | Bayer Ag, 5090 Leverkusen | Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung |
JPS59101423A (ja) * | 1982-12-02 | 1984-06-12 | Takada Seiyaku Kk | 新規なニフエジピン固形製剤 |
US4529733A (en) * | 1983-04-06 | 1985-07-16 | Merrell Dow Pharmaceuticals Inc. | Antihypertensive 3-furoyl-1,4-dihydropyridines |
DE3318649A1 (de) * | 1983-05-21 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | Zweiphasenformulierung |
NL194389C (nl) * | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
IT1178511B (it) * | 1984-09-14 | 1987-09-09 | Pharmatec Spa | Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio |
IT1187751B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute |
US4940556A (en) * | 1986-01-30 | 1990-07-10 | Syntex (U.S.A.) Inc. | Method of preparing long acting formulation |
US5198226A (en) * | 1986-01-30 | 1993-03-30 | Syntex (U.S.A.) Inc. | Long acting nicardipine hydrochloride formulation |
CH673947A5 (fr) * | 1986-09-23 | 1990-04-30 | Sandoz Ag | |
JPS6464659A (en) * | 1987-09-03 | 1989-03-10 | Kenbi Kogaku Kenkyusho Kk | Preparation of safe and effective powder formulation |
SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
DE3814532A1 (de) * | 1988-04-29 | 1989-11-09 | Bayer Ag | Dhp-retard-zubereitung |
JPH0298550U (fr) * | 1989-01-25 | 1990-08-06 | ||
GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
US5271944A (en) * | 1991-04-05 | 1993-12-21 | Biofor, Ltd. | Pharmacologically enhanced formulations |
DE4130173A1 (de) * | 1991-09-11 | 1993-03-18 | Bayer Ag | Pharmazeutische zubereitungen mit einer speziellen kristallmodifikation des 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsaeure-isopropyl-(2-methoxyethyl)-esters |
GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5773025A (en) | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US6726930B1 (en) | 1993-09-09 | 2004-04-27 | Penwest Pharmaceuticals Co. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5543099A (en) * | 1994-09-29 | 1996-08-06 | Hallmark Pharmaceutical, Inc. | Process to manufacture micronized nifedipine granules for sustained release medicaments |
DK0800392T3 (da) * | 1994-12-29 | 2002-03-18 | Shire Deutschland Gmbh & Co Kg | Farmaceutiske præparater med indhold af nifedipin samt fremgangsmåde til fremstilling deraf |
JP3220373B2 (ja) | 1995-11-28 | 2001-10-22 | バイエル薬品株式会社 | 持続性ニフエジピン製剤 |
KR100321489B1 (ko) | 1996-07-08 | 2002-10-09 | 에드워드 멘델 컴파니 인코포레이티드 | 고용량의불용성약물용서방성매트릭스 |
IT1284604B1 (it) * | 1996-09-27 | 1998-05-21 | Roberto Valducci | Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva |
US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
IL143375A0 (en) | 1999-09-30 | 2002-04-21 | Penwest Pharmaceuticals Co | Sustained release matrix systems for highly soluble drugs |
RU2378272C2 (ru) | 2004-07-30 | 2010-01-10 | Торрент Фармасьютикалз Лимитед | Небиволол и его фармацевтически приемлемые соли, способ их получения и фармацевтические композиции небиволола |
DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3330727A (en) * | 1960-04-19 | 1967-07-11 | Glaxo Lab Ltd | Griseofulvin with high specific surface area |
US3401221A (en) * | 1964-08-25 | 1968-09-10 | Norwich Pharma Co | Treatment of urinary tract infection |
DE2348334C2 (de) * | 1973-09-26 | 1982-11-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue Zubereitungsform des N-4-[2-(5-Chlor-2-methoxybenzamido)äthyl]- phenyl-sulfonyl-N'-cyclohexylharnstoffs |
DE2400819C2 (de) * | 1974-01-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung |
GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
JPS55129221A (en) * | 1979-03-29 | 1980-10-06 | Kaken Pharmaceut Co Ltd | Preparation of oral preparation containing hardly soluble medicine |
CA1146866A (fr) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Procede de production d'un compose pharmaceutique a liberation continue sous forme solide |
-
1980
- 1980-09-09 DE DE19803033919 patent/DE3033919A1/de not_active Ceased
- 1980-12-27 JP JP55185148A patent/JPS5914446B2/ja not_active Expired
-
1981
- 1981-08-25 NO NO812879A patent/NO157368B/no unknown
- 1981-08-28 DE DE8181106729T patent/DE3161838D1/de not_active Expired
- 1981-08-28 EP EP81106729A patent/EP0047899B2/fr not_active Expired - Lifetime
- 1981-08-28 AT AT81106729T patent/ATE5761T1/de not_active IP Right Cessation
- 1981-08-31 PT PT73603A patent/PT73603B/pt unknown
- 1981-08-31 PH PH26121A patent/PH24097A/en unknown
- 1981-09-01 DD DD81232939A patent/DD201974A5/de not_active IP Right Cessation
- 1981-09-07 GR GR65968A patent/GR78237B/el unknown
- 1981-09-07 FI FI812758A patent/FI72648B/fi not_active Application Discontinuation
- 1981-09-07 NZ NZ198285A patent/NZ198285A/en unknown
- 1981-09-07 IL IL63749A patent/IL63749A/xx not_active IP Right Cessation
- 1981-09-08 AR AR286686A patent/AR226377A1/es active
- 1981-09-08 IE IE2075/81A patent/IE51549B1/en not_active IP Right Cessation
- 1981-09-08 CA CA000385365A patent/CA1180277A/fr not_active Expired
- 1981-09-08 AU AU75063/81A patent/AU558331B2/en not_active Expired
- 1981-09-08 PL PL23295181A patent/PL232951A1/xx unknown
- 1981-09-08 DK DK396381A patent/DK154326C/da not_active IP Right Cessation
- 1981-09-08 ZA ZA816213A patent/ZA816213B/xx unknown
- 1981-09-09 HU HU812594A patent/HU184879B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
NZ198285A (en) | 1984-04-27 |
PH24097A (en) | 1990-03-05 |
IE51549B1 (en) | 1987-01-07 |
FI812758L (fi) | 1982-03-10 |
DE3161838D1 (en) | 1984-02-09 |
IE812075L (en) | 1982-03-09 |
AU558331B2 (en) | 1987-01-29 |
FI72648B (fi) | 1987-03-31 |
GR78237B (fr) | 1984-09-26 |
IL63749A (en) | 1984-06-29 |
DK154326C (da) | 1995-03-13 |
HU184879B (en) | 1984-10-29 |
DE3033919A1 (de) | 1982-04-22 |
DK154326B (da) | 1988-11-07 |
EP0047899A1 (fr) | 1982-03-24 |
ZA816213B (en) | 1982-09-29 |
NO157368B (no) | 1987-11-30 |
NO812879L (no) | 1982-03-10 |
EP0047899B2 (fr) | 1996-02-28 |
JPS5914446B2 (ja) | 1984-04-04 |
AU7506381A (en) | 1982-03-18 |
CA1180277A (fr) | 1985-01-02 |
AR226377A1 (es) | 1982-06-30 |
EP0047899B1 (fr) | 1984-01-04 |
PT73603B (en) | 1982-11-10 |
DK396381A (da) | 1982-03-10 |
JPS5750913A (en) | 1982-03-25 |
IL63749A0 (en) | 1981-12-31 |
ATE5761T1 (de) | 1984-01-15 |
PT73603A (en) | 1981-09-01 |
PL232951A1 (fr) | 1982-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0047899B1 (fr) | Compositions pharmaceutiques solides contenant de la nifédipine et procédé pour leur préparation | |
EP0126379B1 (fr) | Formulation à deux phases | |
DE3636123C2 (fr) | ||
DE60118008T2 (de) | Pharmazeutische zusammensetzungen mit amlodipinmaleat | |
DE19541128C2 (de) | Stabilisierte schilddrüsenhormonhaltige Arzneimittel | |
DE2822882A1 (de) | Nifedipine-enthaltende feste praeparatzusammensetzung, verfahren zu ihrer herstellung und ihre verwendung | |
DE3915347A1 (de) | Harzadsorbat und verfahren zu seiner herstellung | |
DE2224534B2 (de) | Pharmazeutisches praeparat mit langsamer wirkstoffabgabe | |
DE3720757A1 (de) | Dhp-manteltablette | |
DE69814850T2 (de) | Paracetamol enthaltende schlickbare tablette | |
EP0607775A2 (fr) | Utilisation de leflunomid pour inhiber interleukin 1 bêta | |
EP0607776A2 (fr) | Utilisation de leflunomid pour inhiber le facteur alpha de necrose tumorale | |
DE3212736A1 (de) | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung | |
DE60103276T2 (de) | Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält | |
DE3419131A1 (de) | Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung | |
EP0531845B1 (fr) | Composition pharmaceutique comprenant une modification crystalline spéciale de la 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridine dicarboxylic acide-(-2-méthoxyéthyl)-isopropyl ester | |
DD242349A5 (de) | Verfahren zur herstellung einer synergistischen kombination von flupirtin und 4-acetamido-phenol | |
DE60220953T2 (de) | Pharmazeutische zusammensetzungen enthaltend eine antihistaminische abschwellende arzneistoffkombination und ein verfahren zur herstellung davon | |
DE3419130A1 (de) | Nifedipinkombinationspraeparate und verfahren zu ihrer herstellung | |
DE3639073A1 (de) | Feste arzneizubereitungen und verfahren zu ihrer herstellung | |
DE2629200A1 (de) | Oral verabfolgbares festes antidepressionsmittel und dessen herstellung | |
DE2532180C2 (de) | Verwendung von Etozolin bei der Bekämpfung der Hypertonie | |
EP0800392B1 (fr) | Preparations pharmaceutiques contenant de la nifedipine et procedes permettant de les preparer | |
DE4023136A1 (de) | Neue galenische, orale form zur verbesserung der bioverfuegbarkeit von medikamenten | |
DE3511236A1 (de) | Praeparat mit synergistischer bronchienerweiternder wirkung und verfahren zu dessen herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PV | Patent disclaimer (addendum to changes before extension act) |