DD150223A5 - Verfahren zur herstellung von steroiden - Google Patents

Verfahren zur herstellung von steroiden Download PDF

Info

Publication number
DD150223A5
DD150223A5 DD79220688A DD22068879A DD150223A5 DD 150223 A5 DD150223 A5 DD 150223A5 DD 79220688 A DD79220688 A DD 79220688A DD 22068879 A DD22068879 A DD 22068879A DD 150223 A5 DD150223 A5 DD 150223A5
Authority
DD
German Democratic Republic
Prior art keywords
group
dione
steroids
pregnene
hydrogen atom
Prior art date
Application number
DD79220688A
Other languages
German (de)
English (en)
Inventor
Helmut Dahl
Ernst Schoettle
Reinhold Wieske
Alfred Weber
Mario Kennecke
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DD150223A5 publication Critical patent/DD150223A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60WCONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
    • B60W2510/00Input parameters relating to a particular sub-units
    • B60W2510/10Change speed gearings
    • B60W2510/107Temperature
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60WCONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
    • B60W2720/00Output or target parameters relating to overall vehicle dynamics
    • B60W2720/10Longitudinal speed
    • B60W2720/106Longitudinal acceleration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD79220688A 1978-01-25 1979-01-23 Verfahren zur herstellung von steroiden DD150223A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782803660 DE2803660A1 (de) 1978-01-25 1978-01-25 Neue in 17-position substituierte steroide der pregnanreihe, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
DD150223A5 true DD150223A5 (de) 1981-08-19

Family

ID=6030585

Family Applications (2)

Application Number Title Priority Date Filing Date
DD79220688A DD150223A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von steroiden
DD79210600A DD141524A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von steroiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD79210600A DD141524A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von steroiden

Country Status (17)

Country Link
US (1) US4224320A (da)
EP (1) EP0003519A1 (da)
JP (1) JPS54145649A (da)
AT (1) AT371824B (da)
AU (1) AU529413B2 (da)
CA (1) CA1139743A (da)
CS (1) CS212218B2 (da)
DD (2) DD150223A5 (da)
DE (1) DE2803660A1 (da)
DK (1) DK28679A (da)
ES (1) ES477161A1 (da)
GB (1) GB2013685A (da)
GR (1) GR73667B (da)
HU (1) HU184189B (da)
IE (1) IE790135L (da)
IL (1) IL56495A0 (da)
SU (1) SU860708A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952003A1 (de) * 1979-12-21 1981-07-02 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue kortikoid-17-thioacetale, ihre herstellung und verwendung
FR2552766B1 (fr) * 1983-10-04 1987-06-26 Theramex Nouveau procede de preparation de derives de la serie du 17 a-hydroxy 19-nor progesterone
US4588683A (en) * 1984-02-06 1986-05-13 Eastman Kodak Company Method of preparing 11β, 17α, 20, 21-tetrahydroxy steroids and corresponding 11β, 17α, 21-trihydroxy-20-oxo steroids
US4588525A (en) * 1984-02-27 1986-05-13 Molecular Biosystems, Inc. Prodrug compounds for dermal application
JP2562134B2 (ja) * 1986-09-19 1996-12-11 喜徳 喜谷 新規な白金−ステロイド錯体
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5710293A (en) * 1995-10-13 1998-01-20 The Population Council, Center For Biomedical Research Method of preparation of ester derivatives of steroids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2924597A (en) * 1958-04-08 1960-02-09 Ormonaterapia Richter S P A Process for the preparation of 17alpha hydroxy-progesterone, esters thereof, and intermediates therefor
US3187025A (en) * 1963-06-11 1965-06-01 Smith Kline French Lab Process for preparing compound s
DE1543245C3 (de) * 1965-11-26 1974-07-18 Merck Patent Gmbh, 6100 Darmstadt 16-Methy len-19-norprogesteronderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
NL6605514A (da) * 1966-04-25 1967-10-26
US3530117A (en) * 1969-01-09 1970-09-22 Merck & Co Inc Delta**4 and delta**4,6 - 17 - hydroxy - steroidal pyrazoles of the pregnane series

Also Published As

Publication number Publication date
ES477161A1 (es) 1979-07-01
AU4366579A (en) 1979-08-02
IL56495A0 (en) 1979-03-12
ATA50379A (de) 1982-12-15
AU529413B2 (en) 1983-06-09
DD141524A5 (de) 1980-05-07
AT371824B (de) 1983-08-10
IE790135L (en) 1979-07-25
GR73667B (da) 1984-03-28
DK28679A (da) 1979-07-26
DE2803660A1 (de) 1979-07-26
HU184189B (en) 1984-07-30
CA1139743A (en) 1983-01-18
CS212218B2 (en) 1982-03-26
US4224320A (en) 1980-09-23
EP0003519A1 (de) 1979-08-22
GB2013685A (en) 1979-08-15
JPS54145649A (en) 1979-11-14
SU860708A1 (ru) 1981-08-30

Similar Documents

Publication Publication Date Title
DE2340591A1 (de) Steroidverbindungen
EP0749438B1 (de) Neue silylverbindungen und ihre verwendung
DD150223A5 (de) Verfahren zur herstellung von steroiden
DD219200A5 (de) Verfahren zur herstellung neuer 6alpha-methylkortikoide
DE3102397A1 (de) 17(alpha)-acyloxy-5(beta)-corticoide und 17(alpha)-acyloxy-5(alpha)-corticoide
EP0591268A1 (de) Verfahren zur herstellung von 6-methylensteroiden
CH632279A5 (en) Process for the preparation of polyhalogenated steroids
EP0003341B1 (de) 11,17-substituierte Pregnane, ihre Herstellung und Verwendung zur Herstellung von pharmazeutischen Präparaten
DD158778A5 (de) Verfahren zur herstellung halogenierter steroide
DE60215193T2 (de) Stereoselektives verfahren zur herstellung von 6alpha-fluorpregnanen und zwischenprodukten
US4340538A (en) Process for producing 6α-fluoro-Δ1,4 -3-keto steroids
US4353985A (en) Process for the preparation of 11 β-hydroxy steroids
DE2349023A1 (de) Neue d-homo-steroide
DE2453823A1 (de) Neue methylensteroide
US4025563A (en) Novel D-homo steroids
DE1125422B (de) Verfahren zur Herstellung von 6-Fluor-í¸-3-ketosteoriden
DE1131213B (de) Verfahren zur Herstellung neuer Pregnanverbindungen
DE2803661A1 (de) Neue in 17-position substituierte 11beta-hydroxysteroide der pregnanreihe, ihre herstellung und verwendung
DE2905674A1 (de) Steroidverbindungen und verfahren zu ihrer herstellung
CA1144538A (en) Steroids of the pregnane series substituted in the 17-position, and their manufacture and use
DE2521231A1 (de) Verfahren zur herstellung von 21- hydroxy-16-pregnen-20-on-derivaten
CH625254A5 (da)
EP0049783B1 (de) D-Homo-kortikoide, ihre Herstellung und Verwendung
DE1793750C3 (de) Verfahren zur Herstellung von Fluorverbindungen der Pregnanreihe
DE1618936C3 (de) Verfahren zur Herstellung von Fluorverbindungen der Pregnanreihe. Ausscheidung aus: 1418394 Anmr Syntex S.A., Mexico City