CZ300690B6 - Farmaceutická kombinace obsahující tegaserod a omeprazol pro lécení refluxní nemoci jícnu - Google Patents

Farmaceutická kombinace obsahující tegaserod a omeprazol pro lécení refluxní nemoci jícnu Download PDF

Info

Publication number
CZ300690B6
CZ300690B6 CZ20021967A CZ20021967A CZ300690B6 CZ 300690 B6 CZ300690 B6 CZ 300690B6 CZ 20021967 A CZ20021967 A CZ 20021967A CZ 20021967 A CZ20021967 A CZ 20021967A CZ 300690 B6 CZ300690 B6 CZ 300690B6
Authority
CZ
Czechia
Prior art keywords
tegaserod
pharmaceutically acceptable
omeprazole
acceptable salt
agent
Prior art date
Application number
CZ20021967A
Other languages
Czech (cs)
English (en)
Other versions
CZ20021967A3 (cs
Inventor
Anthony Billstein@Stephan
Dumovic@Peter
Franco@Nicola
Thomas Iwicki@Mark
Pfannkuche@Hans-Jürgen
Joseph Wilusz@Edward
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CZ20021967A3 publication Critical patent/CZ20021967A3/cs
Publication of CZ300690B6 publication Critical patent/CZ300690B6/cs

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CZ20021967A 1999-12-10 2000-12-08 Farmaceutická kombinace obsahující tegaserod a omeprazol pro lécení refluxní nemoci jícnu CZ300690B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45838899A 1999-12-10 1999-12-10

Publications (2)

Publication Number Publication Date
CZ20021967A3 CZ20021967A3 (cs) 2002-08-14
CZ300690B6 true CZ300690B6 (cs) 2009-07-15

Family

ID=23820591

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20021967A CZ300690B6 (cs) 1999-12-10 2000-12-08 Farmaceutická kombinace obsahující tegaserod a omeprazol pro lécení refluxní nemoci jícnu

Country Status (30)

Country Link
EP (3) EP1488788A1 (https=)
JP (1) JP2003523324A (https=)
KR (1) KR100765579B1 (https=)
CN (2) CN1310644C (https=)
AR (1) AR026916A1 (https=)
AT (1) ATE293971T1 (https=)
AU (2) AU778869B2 (https=)
BR (1) BR0016275A (https=)
CA (1) CA2388959A1 (https=)
CO (1) CO5261535A1 (https=)
CZ (1) CZ300690B6 (https=)
DE (1) DE60019814T2 (https=)
DK (1) DK1286668T3 (https=)
ES (1) ES2240229T3 (https=)
HU (1) HUP0301122A3 (https=)
IL (2) IL149496A0 (https=)
MX (1) MXPA02005695A (https=)
MY (1) MY133423A (https=)
NO (1) NO20022680L (https=)
NZ (2) NZ531489A (https=)
PE (1) PE20011030A1 (https=)
PL (1) PL202201B1 (https=)
PT (1) PT1286668E (https=)
RU (1) RU2264215C2 (https=)
SG (1) SG152025A1 (https=)
SK (1) SK8062002A3 (https=)
TR (1) TR200402293T2 (https=)
TW (1) TWI263496B (https=)
WO (1) WO2001041748A2 (https=)
ZA (1) ZA200204493B (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1284732A2 (en) * 2000-05-18 2003-02-26 Glaxo Group Limited Method for treating functional dyspepsia using alosetron
GB0209481D0 (en) * 2002-04-24 2002-06-05 Novartis Ag Organic compounds
JP2006516977A (ja) 2003-01-13 2006-07-13 ダイノゲン ファーマシューティカルズ,インコーポレイテッド 悪心、嘔吐、レッチング、またはそれらの任意の組み合わせの治療方法
GB0307440D0 (en) * 2003-03-31 2003-05-07 Novartis Ag Organic compounds
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
US20050090554A1 (en) * 2003-09-12 2005-04-28 John Devane Treatment of gastroparesis and nonulcer dyspepsia with GABAB agonists
US7820690B2 (en) 2004-03-19 2010-10-26 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
AU2005261778A1 (en) * 2004-07-14 2006-01-19 Novartis Ag Combination of DPP-IV inhibitors and compounds modulating 5-HT3 and/or 5-HT4 receptors
AU2006211205A1 (en) * 2005-01-31 2006-08-10 Novartis Ag Organic compounds
GB0506800D0 (en) * 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP2009525269A (ja) 2006-01-30 2009-07-09 ユーロ−セルティーク エス.エイ. カルシウムチャネルブロッカーとしての環状尿素化合物
CN101466368A (zh) * 2006-06-15 2009-06-24 诺瓦提斯公司 用于治疗或者预防胃损伤的仅包括替加色罗或者包括替加色罗与质子泵抑制剂组合的组合物
CN101657436A (zh) 2007-02-09 2010-02-24 特兰齐姆制药公司 大环生长素释放肽受体调节剂及其使用方法
US8865692B2 (en) 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
US20090149433A1 (en) 2007-11-13 2009-06-11 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
RU2769282C2 (ru) 2016-06-20 2022-03-30 Кимаб Лимитед Анти-PD-L1 и IL-2 цитокины
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
WO2018029474A2 (en) 2016-08-09 2018-02-15 Kymab Limited Anti-icos antibodies
US11858996B2 (en) 2016-08-09 2024-01-02 Kymab Limited Anti-ICOS antibodies
EP3534947A1 (en) 2016-11-03 2019-09-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
GB201709808D0 (en) 2017-06-20 2017-08-02 Kymab Ltd Antibodies
GB201721338D0 (en) 2017-12-19 2018-01-31 Kymab Ltd Anti-icos Antibodies
EP3728314A1 (en) 2017-12-19 2020-10-28 Kymab Limited Bispecific antibody for icos and pd-l1
TW202313682A (zh) 2021-05-18 2023-04-01 英商凱麥博有限公司 抗icos抗體之用途
GB202107994D0 (en) 2021-06-04 2021-07-21 Kymab Ltd Treatment of cancer
WO2023222854A1 (en) 2022-05-18 2023-11-23 Kymab Limited Uses of anti-icos antibodies
FR3144752A1 (fr) 2023-01-10 2024-07-12 Song Huang Utilisation de polysulfate de pentosane pour le traitement de la toux seche

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0505322A1 (en) * 1991-03-22 1992-09-23 Sandoz Ltd. Aminoguanidines
WO1993012785A1 (en) * 1991-12-21 1993-07-08 Smithkline Beecham Plc Use of 5-ht4 modulators for the manufacture of a medicament for the treatment of the bladder diseases
WO1994001095A2 (en) * 1992-07-03 1994-01-20 Smithkline Beecham Plc Medicaments for the treatment of visceral pain and migraine
WO1999017755A2 (en) * 1997-10-07 1999-04-15 Glaxo Group Limited Medicaments

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362756A (en) * 1989-02-20 1994-11-08 Riviere Pierre J M Use of fedotozine in the treatment of functional states of intestinal obstructions
US5932568A (en) * 1994-11-21 1999-08-03 Dainippon Pharmaceutical Co., Ltd. 6-methoxy-1H-benzotriazole-5-carboxamide derivatives and pharmaceutical compositions containing them
US5919760A (en) * 1996-04-12 1999-07-06 Intensive Narcotic Detoxification Centers Of America, Llc Method for treating acute and severe diarrhea
US6156771A (en) * 1997-08-28 2000-12-05 Rubin; Walter Method for alleviation of lower gastrointestinal disorders in a human patient

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0505322A1 (en) * 1991-03-22 1992-09-23 Sandoz Ltd. Aminoguanidines
WO1993012785A1 (en) * 1991-12-21 1993-07-08 Smithkline Beecham Plc Use of 5-ht4 modulators for the manufacture of a medicament for the treatment of the bladder diseases
WO1994001095A2 (en) * 1992-07-03 1994-01-20 Smithkline Beecham Plc Medicaments for the treatment of visceral pain and migraine
WO1999017755A2 (en) * 1997-10-07 1999-04-15 Glaxo Group Limited Medicaments

Also Published As

Publication number Publication date
CN1409634A (zh) 2003-04-09
EP1286668A2 (en) 2003-03-05
ES2240229T3 (es) 2005-10-16
ATE293971T1 (de) 2005-05-15
SG152025A1 (en) 2009-05-29
BR0016275A (pt) 2002-08-27
JP2003523324A (ja) 2003-08-05
KR20030016208A (ko) 2003-02-26
RU2002118316A (ru) 2004-02-20
CO5261535A1 (es) 2003-03-31
PL355663A1 (en) 2004-05-04
TWI263496B (en) 2006-10-11
CZ20021967A3 (cs) 2002-08-14
HUP0301122A2 (hu) 2003-08-28
AU2005200797A1 (en) 2005-03-17
EP1286668B1 (en) 2005-04-27
EP1488788A1 (en) 2004-12-22
MXPA02005695A (es) 2002-09-18
PL202201B1 (pl) 2009-06-30
CN1875966A (zh) 2006-12-13
PT1286668E (pt) 2005-08-31
KR100765579B1 (ko) 2007-10-09
DK1286668T3 (da) 2005-08-15
NO20022680D0 (no) 2002-06-06
ZA200204493B (en) 2003-09-29
AR026916A1 (es) 2003-03-05
NZ566800A (en) 2009-11-27
CN1310644C (zh) 2007-04-18
DE60019814D1 (de) 2005-06-02
AU778869B2 (en) 2004-12-23
AU2672801A (en) 2001-06-18
NZ531489A (en) 2005-09-30
AU2005200797B2 (en) 2008-01-24
WO2001041748A3 (en) 2002-12-19
SK8062002A3 (en) 2003-04-01
RU2264215C2 (ru) 2005-11-20
EP1913944A1 (en) 2008-04-23
PE20011030A1 (es) 2001-10-31
NO20022680L (no) 2002-08-12
HUP0301122A3 (en) 2005-03-29
IL149496A (en) 2009-12-24
IL149496A0 (en) 2002-11-10
TR200402293T2 (tr) 2004-10-21
CA2388959A1 (en) 2001-06-14
MY133423A (en) 2007-11-30
WO2001041748A2 (en) 2001-06-14
DE60019814T2 (de) 2006-03-02

Similar Documents

Publication Publication Date Title
CZ300690B6 (cs) Farmaceutická kombinace obsahující tegaserod a omeprazol pro lécení refluxní nemoci jícnu
US20080090878A1 (en) Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders
ES2388501T3 (es) Uso de secretagogos de la hormona de crecimiento para estimular la motilidad del sistema gastrointestinal
MX2007000507A (es) Combinacion de inhibidores de dpp-iv y compuestos que modulan a los receptores 5-ht3 y/o 5-ht4.
JPH08502031A (ja) 胃食道逆流疾患およびその他の障害を治療するために▲(+)▼シサプリドを使用する方法
Zyad et al. GERD: Latest update on acid-suppressant drugs
AU2001256685B2 (en) Pharmaceutical compositions containing aminothiazole derivatives for the treatment of colonic motor dysfunctions
US20090221665A1 (en) Organic Compounds
WO2022246298A1 (en) Methods of treating interstitial cystitis/bladder pain syndrome
CN101138563A (zh) 治疗消化性溃疡药物组合物
CN102920705A (zh) 泰妥拉唑在制造治疗胃食管反流性疾病的药物中的应用
JP2023052054A (ja) トリアザスピロ[4.5]デカノンによる胃不全麻痺の処置
WO2024141073A1 (en) Pharmaceutical combinations and compositions, and methods of use thereof
EP4543428A1 (en) Methods of treating or preventing overactive bladder syndrome
CN101492452A (zh) 含有二氧杂环庚烷并吡啶的巯基苯并咪唑衍生物
CN1785429A (zh) 一种治疗消化性溃疡药物组合物
Vet—QA04AA03 Timepidium Bromide (rINN)
HK1105279B (en) Use of growth hormone secretagogues for stimulating the motility of the gastrointestinal system

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of fee

Effective date: 20101208