CZ289043B6 - Farmaceutický prostředek k léčení diabetu mellitus typu II - Google Patents

Farmaceutický prostředek k léčení diabetu mellitus typu II Download PDF

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Publication number
CZ289043B6
CZ289043B6 CZ1997337A CZ33797A CZ289043B6 CZ 289043 B6 CZ289043 B6 CZ 289043B6 CZ 1997337 A CZ1997337 A CZ 1997337A CZ 33797 A CZ33797 A CZ 33797A CZ 289043 B6 CZ289043 B6 CZ 289043B6
Authority
CZ
Czechia
Prior art keywords
amylin
insulin
pro
dependent
patients
Prior art date
Application number
CZ1997337A
Other languages
Czech (cs)
English (en)
Other versions
CZ33797A3 (en
Inventor
Orville G. Kolterman
Robert G. Thompson
John F. Mullane
Original Assignee
Amylin Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals, Inc. filed Critical Amylin Pharmaceuticals, Inc.
Publication of CZ33797A3 publication Critical patent/CZ33797A3/cs
Publication of CZ289043B6 publication Critical patent/CZ289043B6/cs

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CZ1997337A 1995-06-07 1996-06-07 Farmaceutický prostředek k léčení diabetu mellitus typu II CZ289043B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/483,188 US6143718A (en) 1995-06-07 1995-06-07 Treatment of Type II diabetes mellutis with amylin agonists
PCT/US1996/009875 WO1996040220A1 (en) 1995-06-07 1996-06-07 Treatment of type ii diabetes mellitus with amylin agonists

Publications (2)

Publication Number Publication Date
CZ33797A3 CZ33797A3 (en) 1997-07-16
CZ289043B6 true CZ289043B6 (cs) 2001-10-17

Family

ID=23919034

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ1997337A CZ289043B6 (cs) 1995-06-07 1996-06-07 Farmaceutický prostředek k léčení diabetu mellitus typu II

Country Status (19)

Country Link
US (2) US6143718A (en:Method)
EP (1) EP0772451B1 (en:Method)
JP (1) JP4009319B2 (en:Method)
AT (1) ATE228849T1 (en:Method)
AU (1) AU721489B2 (en:Method)
BG (1) BG101230A (en:Method)
CA (1) CA2196999C (en:Method)
CZ (1) CZ289043B6 (en:Method)
DE (1) DE69625157T2 (en:Method)
DK (1) DK0772451T3 (en:Method)
ES (1) ES2187659T3 (en:Method)
HU (1) HUP9700368A3 (en:Method)
IN (1) IN181672B (en:Method)
NO (1) NO970519L (en:Method)
PT (1) PT772451E (en:Method)
RU (1) RU2166958C2 (en:Method)
SK (1) SK18697A3 (en:Method)
WO (1) WO1996040220A1 (en:Method)
ZA (1) ZA964838B (en:Method)

Families Citing this family (40)

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HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
JP3821839B2 (ja) * 1993-09-07 2006-09-13 アミリン・ファーマシューティカルズ,インコーポレイテッド 胃腸の運動性を調節する方法
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
EP1044015B1 (en) * 1998-01-09 2008-10-08 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides with insulin
US6087334A (en) * 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides
ES2316757T3 (es) * 2002-01-08 2009-04-16 Amylin Pharmaceuticals, Inc. Uso de agonistas de amilina para modular trigliceridos.
JP4579681B2 (ja) * 2002-07-09 2010-11-10 ブリストル−マイヤーズ スクイブ カンパニー 抗糖尿病薬および抗肥満薬として有用な置換ヘテロシクロ誘導体および方法
US20050009748A1 (en) * 2003-05-14 2005-01-13 Emisphere Technologies, Inc. Compositions for delivering peptide YY and PYY agonists
EP1644027B1 (en) * 2003-07-16 2014-04-09 Evotec International GmbH Use of pleiotrophin for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome
BRPI0507623A (pt) 2004-02-11 2007-07-03 Amylin Pharmaceuticals Inc peptìdeos da famìlia da amilina e métodos para prepará-los e empregá-los
WO2005082401A1 (en) * 2004-02-20 2005-09-09 Rinat Neuroscience Corp. Methods of treating obesity or diabetes using nt-4/5
US7399744B2 (en) * 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
US7759312B2 (en) * 2005-03-11 2010-07-20 Endo Pharmaceuticals Solutions Inc. Delivery of dry formulations of octreotide
NZ561400A (en) * 2005-03-11 2010-02-26 Endo Pharmaceuticals Solutions Controlled release formulations of octreotide
CN101400367A (zh) * 2006-02-02 2009-04-01 瑞纳神经科学公司 施用trkb激动剂治疗不希望的重量减轻或进食障碍的方法
JP2009525319A (ja) * 2006-02-02 2009-07-09 ライナット ニューロサイエンス コーポレイション trkBアンタゴニストを投与することにより肥満を治療する方法
CN101605556A (zh) * 2006-12-20 2009-12-16 瑞纳神经科学公司 治疗自体免疫疾病的trkb激动剂
AU2007360979B2 (en) * 2007-11-14 2014-04-10 Amylin Pharmaceuticals, Llc Methods for treating obesity and obesity related diseases and disorders
WO2009158415A1 (en) 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Octreotide implant having a release agent
WO2009158412A2 (en) 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
CN102369018B (zh) * 2009-03-12 2016-08-03 关键生物科学有限公司 糖尿病和代谢综合征的治疗
CN107308442B (zh) 2009-11-13 2022-10-18 赛诺菲-安万特德国有限公司 包含glp-1激动剂、胰岛素和甲硫氨酸的药物组合物
AU2010317994B2 (en) 2009-11-13 2014-03-06 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
US20110118180A1 (en) * 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Method of treatment of diabetes type 2 comprising add-on therapy to metformin
US20110118178A1 (en) * 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Method of treatment of diabetes type 2 comprising add-on therapy to insulin glargine and metformin
PL2611458T3 (pl) 2010-08-30 2017-02-28 Sanofi-Aventis Deutschland Gmbh Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
BR102013017626A2 (pt) * 2013-06-14 2015-02-10 Univ Rio De Janeiro Bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, uso de bioconjugados não aglomerantes de amilinomiméticos com polietilenoglicol, composições farmacêuticas de baixa toxicidade, adjuvante para a prevenção ou tratamento das doenças, medicamento, método de tratamento ou prevenção de doenças.
CN106687474A (zh) * 2014-09-04 2017-05-17 诺和诺德股份有限公司 新型胰淀素和降钙素受体激动剂
TN2017000235A1 (en) 2014-12-12 2018-10-19 Sanofi Aventis Deutschland Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5367052A (en) * 1987-04-27 1994-11-22 Amylin Pharmaceuticals, Inc. Amylin peptides
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
US5266561A (en) * 1988-01-11 1993-11-30 Amylin Pharmaceuticals, Inc. Treatment of type 2 diabetes mellitus
US5175145A (en) * 1988-08-26 1992-12-29 Amylin Pharmaceuticals, Inc. Treatment of diabetes mellitus with amylin agonists
US5321008A (en) * 1991-01-10 1994-06-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
DE69232064T2 (de) * 1991-11-19 2002-03-28 Amylin Pharmaceuticals, Inc. Peptide als Amylin-Agonisten und ihre Verwendung
US5376638A (en) * 1992-09-01 1994-12-27 Amylin Pharmaceuticals, Inc. Methods for treating renin-related disorders with amylin antagonists
JP3821839B2 (ja) * 1993-09-07 2006-09-13 アミリン・ファーマシューティカルズ,インコーポレイテッド 胃腸の運動性を調節する方法
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US6087334A (en) 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides

Also Published As

Publication number Publication date
EP0772451A4 (en) 1998-09-30
WO1996040220A1 (en) 1996-12-19
HU9700368D0 (en) 1997-04-28
ZA964838B (en) 1997-02-24
ATE228849T1 (de) 2002-12-15
HUP9700368A3 (en) 2001-03-28
NO970519D0 (no) 1997-02-05
DE69625157T2 (de) 2003-04-17
RU2166958C2 (ru) 2001-05-20
HUP9700368A2 (hu) 1998-06-29
DK0772451T3 (da) 2003-01-06
IN181672B (en:Method) 1998-08-29
CZ33797A3 (en) 1997-07-16
US6143718A (en) 2000-11-07
CA2196999C (en) 2012-09-04
JPH10503785A (ja) 1998-04-07
JP4009319B2 (ja) 2007-11-14
EP0772451A1 (en) 1997-05-14
ES2187659T3 (es) 2003-06-16
AU721489B2 (en) 2000-07-06
PT772451E (pt) 2003-04-30
BG101230A (en) 1997-10-31
NO970519L (no) 1997-04-07
CA2196999A1 (en) 1996-12-19
DE69625157D1 (de) 2003-01-16
US6417164B1 (en) 2002-07-09
SK18697A3 (en) 1998-02-04
EP0772451B1 (en) 2002-12-04
AU6268596A (en) 1996-12-30

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20150607