CZ280504B6 - Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití - Google Patents

Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití Download PDF

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Publication number
CZ280504B6
CZ280504B6 CS92425A CS42592A CZ280504B6 CZ 280504 B6 CZ280504 B6 CZ 280504B6 CS 92425 A CS92425 A CS 92425A CS 42592 A CS42592 A CS 42592A CZ 280504 B6 CZ280504 B6 CZ 280504B6
Authority
CZ
Czechia
Prior art keywords
compounds
formula
pyrid
methylimidazo
piperidine
Prior art date
Application number
CS92425A
Other languages
Czech (cs)
English (en)
Inventor
David Dr. Alker
Robert John Dr. Bass
Kelvin Dr. Cooper
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CS42592A3 publication Critical patent/CS42592A3/cs
Publication of CZ280504B6 publication Critical patent/CZ280504B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Cosmetics (AREA)
  • Steroid Compounds (AREA)
CS92425A 1991-02-13 1992-02-12 Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití CZ280504B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents

Publications (2)

Publication Number Publication Date
CS42592A3 CS42592A3 (en) 1992-09-16
CZ280504B6 true CZ280504B6 (cs) 1996-02-14

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
CS92425A CZ280504B6 (cs) 1991-02-13 1992-02-12 Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití

Country Status (29)

Country Link
US (1) US5358953A (enrdf_load_html_response)
EP (1) EP0572425B1 (enrdf_load_html_response)
JP (1) JP2506541B2 (enrdf_load_html_response)
KR (1) KR970005302B1 (enrdf_load_html_response)
CN (1) CN1040326C (enrdf_load_html_response)
AT (1) ATE109482T1 (enrdf_load_html_response)
AU (1) AU650322B2 (enrdf_load_html_response)
BR (1) BR9205615A (enrdf_load_html_response)
CA (1) CA2099381C (enrdf_load_html_response)
CZ (1) CZ280504B6 (enrdf_load_html_response)
DE (1) DE69200304T2 (enrdf_load_html_response)
DK (1) DK0572425T3 (enrdf_load_html_response)
EG (1) EG20085A (enrdf_load_html_response)
ES (1) ES2059212T3 (enrdf_load_html_response)
FI (1) FI933531A0 (enrdf_load_html_response)
GB (1) GB9102997D0 (enrdf_load_html_response)
HU (2) HUT65947A (enrdf_load_html_response)
IE (1) IE65125B1 (enrdf_load_html_response)
IL (1) IL100887A (enrdf_load_html_response)
MX (1) MX9200589A (enrdf_load_html_response)
MY (1) MY108437A (enrdf_load_html_response)
NO (1) NO300592B1 (enrdf_load_html_response)
NZ (1) NZ241597A (enrdf_load_html_response)
PL (1) PL169304B1 (enrdf_load_html_response)
RU (1) RU2114845C1 (enrdf_load_html_response)
TW (1) TW227000B (enrdf_load_html_response)
WO (1) WO1992014734A1 (enrdf_load_html_response)
YU (1) YU48238B (enrdf_load_html_response)
ZA (1) ZA921005B (enrdf_load_html_response)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
EP0775139A1 (en) * 1994-08-10 1997-05-28 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
AU698487B2 (en) * 1995-08-05 1998-10-29 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
DK1311269T3 (da) 2000-08-04 2012-03-26 Dmi Biosciences Inc Fremgangsmåde til anvendelse af diketopiperaziner og sammensætning, som indeholder dem
KR20060022659A (ko) 2003-05-15 2006-03-10 디엠아이 바이오사이언시스, 인크 Ｔ-세포 매개성 질환의 치료 방법
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
US8377967B2 (en) 2008-01-30 2013-02-19 Nippon Zoki Pharmaceutical Co., Ltd. Piperidine derivative
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
EP2727919B1 (en) * 2011-06-28 2019-05-08 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Benzocycloheptanethiophene derivatives for anti-allergic reactions
BR112014007657A2 (pt) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
SG10201608103YA (en) 2011-10-10 2016-11-29 Ampio Pharmaceuticals Inc Treatment of degenerative joint disease
HK1198812A1 (en) * 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
CN105101965B (zh) 2013-03-15 2021-03-09 安皮奥制药股份有限公司 用于干细胞活动化、归巢、扩增和分化的组合物及其使用方法
AU2015305611B2 (en) 2014-08-18 2020-04-23 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (enrdf_load_html_response) * 1963-04-24
EP0404797B1 (en) * 1988-03-15 1995-02-01 G.D. Searle & Co. 1H/3H-[4-(N,N-CYCLOALKYL AND/OR BRANCHED-ALKYLCARBOXAMIDO) -BENZYL]IMIDAZO[4,5-c]PYRIDINES AS PAF ANTAGONISTS
ES2091195T3 (es) * 1988-04-28 1996-11-01 Schering Corp Compuestos policiclicos condensados, composiciones, metodos de preparacion y su uso como agentes antagonistas de paf, antihistaminicos y/o antiinflamatorios.
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
EP0533695B1 (en) * 1990-05-09 1994-10-05 Pfizer Inc. IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY

Also Published As

Publication number Publication date
AU1168392A (en) 1992-09-15
HU211202A9 (en) 1995-11-28
IE920449A1 (en) 1992-08-12
IE65125B1 (en) 1995-10-04
CA2099381C (en) 1996-07-09
JPH06504992A (ja) 1994-06-09
ZA921005B (en) 1993-08-12
RU2114845C1 (ru) 1998-07-10
IL100887A0 (en) 1992-11-15
FI933531L (fi) 1993-08-10
JP2506541B2 (ja) 1996-06-12
IL100887A (en) 1996-01-19
CA2099381A1 (en) 1992-08-14
CN1040326C (zh) 1998-10-21
PL169304B1 (pl) 1996-06-28
DK0572425T3 (da) 1994-09-12
MX9200589A (es) 1992-10-01
KR970005302B1 (ko) 1997-04-15
HU9302327D0 (en) 1993-10-28
CN1064275A (zh) 1992-09-09
CS42592A3 (en) 1992-09-16
NO932889D0 (no) 1993-08-13
BR9205615A (pt) 1994-05-17
NO932889L (no) 1993-08-13
EP0572425A1 (en) 1993-12-08
EP0572425B1 (en) 1994-08-03
FI933531A7 (fi) 1993-08-10
WO1992014734A1 (en) 1992-09-03
DE69200304D1 (de) 1994-09-08
TW227000B (enrdf_load_html_response) 1994-07-21
MY108437A (en) 1996-09-30
YU48238B (sh) 1997-08-22
HUT65947A (en) 1994-08-29
AU650322B2 (en) 1994-06-16
NZ241597A (en) 1993-04-28
EG20085A (en) 1997-05-31
ES2059212T3 (es) 1994-11-01
DE69200304T2 (de) 1994-12-08
ATE109482T1 (de) 1994-08-15
YU14392A (sh) 1994-11-15
FI933531A0 (fi) 1993-08-10
GB9102997D0 (en) 1991-03-27
NO300592B1 (no) 1997-06-23
US5358953A (en) 1994-10-25

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20000212