CZ20032635A3 - Farmaceutický prostředek na bázi anticholinergik a inhibitorů PDE-IV, způsob jeho výroby a použití - Google Patents
Farmaceutický prostředek na bázi anticholinergik a inhibitorů PDE-IV, způsob jeho výroby a použití Download PDFInfo
- Publication number
- CZ20032635A3 CZ20032635A3 CZ20032635A CZ20032635A CZ20032635A3 CZ 20032635 A3 CZ20032635 A3 CZ 20032635A3 CZ 20032635 A CZ20032635 A CZ 20032635A CZ 20032635 A CZ20032635 A CZ 20032635A CZ 20032635 A3 CZ20032635 A3 CZ 20032635A3
- Authority
- CZ
- Czechia
- Prior art keywords
- acid
- pharmaceutical composition
- inhalable
- propellant
- inhalation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10110772A DE10110772A1 (de) | 2001-03-07 | 2001-03-07 | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ20032635A3 true CZ20032635A3 (cs) | 2004-09-15 |
Family
ID=7676493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ20032635A CZ20032635A3 (cs) | 2001-03-07 | 2002-02-26 | Farmaceutický prostředek na bázi anticholinergik a inhibitorů PDE-IV, způsob jeho výroby a použití |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1372649B1 (enExample) |
| JP (1) | JP2004521134A (enExample) |
| KR (1) | KR20030081501A (enExample) |
| CN (1) | CN1649588A (enExample) |
| AR (1) | AR034213A1 (enExample) |
| AU (1) | AU2002257587B2 (enExample) |
| BR (1) | BR0207883A (enExample) |
| CA (1) | CA2439763C (enExample) |
| CZ (1) | CZ20032635A3 (enExample) |
| DE (1) | DE10110772A1 (enExample) |
| EA (1) | EA009989B1 (enExample) |
| HU (1) | HUP0400782A3 (enExample) |
| IL (2) | IL157326A0 (enExample) |
| MX (1) | MXPA03008045A (enExample) |
| NZ (1) | NZ528621A (enExample) |
| PL (1) | PL363078A1 (enExample) |
| TW (1) | TWI332833B (enExample) |
| WO (1) | WO2002069945A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| WO2002096423A2 (en) * | 2001-05-25 | 2002-12-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Combination of a pde4 inhibitor and tiotropium or derivate thereof for treating obstructive airways |
| GB0118373D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxo Group Ltd | Novel therapeutic method |
| US20030235538A1 (en) | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
| DE10230769A1 (de) * | 2002-07-09 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren |
| WO2004084894A1 (en) * | 2003-03-28 | 2004-10-07 | Altana Pharma Ag | Synergistic combination comprising roflumilast and revatropate for the treatment of respiratory diseases |
| PT1610787E (pt) * | 2003-03-28 | 2008-04-23 | Nycomed Gmbh | Associação sinérgica compreendendo roflumilast e um agente anticolinérgico seleccionado de sais de tiotrópio para o tratamento de doenças respiratórias |
| EP1610788A1 (en) * | 2003-03-28 | 2006-01-04 | ALTANA Pharma AG | Synergistic combination comprising roflumilast and an anticholinergic agent selected from ipratropium, oxitropium and tiotropium salts for the treatment of respiratory diseases |
| TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
| CA2533786A1 (en) * | 2003-07-28 | 2005-02-17 | Boehringer Ingelheim International Gmbh | Medicaments comprising pde iv inhibitors and a novel anticholinergic and their use for treating respiratory disorders |
| US7071333B2 (en) | 2003-07-30 | 2006-07-04 | Bristol-Myers Squibb Company | Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same |
| EP1504756A1 (en) * | 2003-08-06 | 2005-02-09 | Kyowa Hakko Kogyo Co., Ltd | Medicament compositions comprising a heterocyclic compound and an anticholinergic |
| JP2007517820A (ja) * | 2004-01-09 | 2007-07-05 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | スコピンエステル及びニコチンアミド誘導体を基にした新規な医薬組成物 |
| ES2413011T3 (es) | 2004-02-06 | 2013-07-15 | Meda Pharma Gmbh & Co. Kg | Combinación de anticolinérgicos y glucocorticoides para el tratamiento a largo plazo de asma y EPOC |
| CA2550848C (en) * | 2004-02-06 | 2013-02-26 | Meda Pharma Gmbh & Co. Kg | Combination of anticholinergics and inhibitors of phosphodiesterase type 4 for the treatment of respiratory diseases |
| AU2005210086A1 (en) * | 2004-02-06 | 2005-08-18 | Meda Pharma Gmbh & Co. Kg | Treatment of rhinitis with anticholinergics alone in combination with antihistamines phosphodiesterase 4 inhibitors, or corticosteroids |
| JP2007524699A (ja) * | 2004-02-27 | 2007-08-30 | アルタナ ファルマ アクチエンゲゼルシャフト | ロフルミラストとグリコピロニウムとの組合せ物 |
| EP1616567A1 (en) * | 2004-07-16 | 2006-01-18 | Boehringer Ingelheim Pharma GmbH & Co.KG | Medicaments for inhalation comprising PDE IV inhibitors and glycopyrrolate salts |
| SI1863476T1 (sl) | 2005-03-16 | 2016-05-31 | Meda Pharma Gmbh & Co. Kg | Kombinacija antiholinergikov in antagonistov receptorja levkotriena za zdravljenje respiratornih bolezni |
| GB0521563D0 (en) | 2005-10-21 | 2005-11-30 | Glaxo Group Ltd | Novel compounds |
| PL1971369T3 (pl) | 2005-12-21 | 2010-01-29 | Meda Pharma Gmbh & Co Kg | Połączenie R,R-glikopirolanu, rolipramu i budesonidu dla potrzeb leczenia chorób zapalnych |
| NZ574533A (en) | 2006-08-01 | 2011-05-27 | Glaxo Group Ltd | Pyrazolo[3,4-b]pyridine compounds, and their use as pde4 inhibitors |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| CA2749403A1 (en) | 2009-01-13 | 2010-09-02 | Glaxo Group Limited | Pyrimidinecarboxamide derivatives as inhibitors of syk kinase |
| WO2012025473A1 (en) | 2010-08-24 | 2012-03-01 | Glaxo Group Limited | Cc.chemokine receptor 4 antagonists |
| WO2012025474A1 (en) | 2010-08-24 | 2012-03-01 | Glaxo Group Limited | Indazole compounds |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| CN102670607A (zh) * | 2012-05-28 | 2012-09-19 | 海南卫康制药(潜山)有限公司 | 复方盐酸氨溴索组合物及其制备方法 |
| JP6560986B2 (ja) | 2013-03-15 | 2019-08-14 | ヴェローナ ファーマ ピーエルシー | 複合製剤 |
| KR20160016966A (ko) * | 2013-05-31 | 2016-02-15 | 인씨피오 디바이시스 에스에이 | 비구 리머 조립체 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000198734A (ja) * | 1998-12-30 | 2000-07-18 | Pfizer Inc | 胃運動性減弱および関連疾患の治療のための運動性増強薬 |
| MY134008A (en) * | 1999-12-22 | 2007-11-30 | Merck Frosst Canada Inc | Subtituted 8-arylquinoline phospohodiestrase-4 inhibitors |
| CZ20022413A3 (cs) * | 2000-01-31 | 2003-08-13 | Pfizer Products Inc. | Pyrimidinkarboxamidy užitečné jako inhibitory isozymů PDE4 |
| AU2001239550A1 (en) * | 2000-03-23 | 2001-10-03 | Takeda Chemical Industries Ltd. | Furoisoquinoline derivatives, process for producing the same and use thereof |
| GB0009583D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Respiratory formulations |
| US20020052312A1 (en) * | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
| AR029984A1 (es) * | 2000-07-27 | 2003-07-23 | Smithkline Beecham Corp | Metodo para reducir las exacerbaciones asociadas copd ambito |
-
2001
- 2001-03-07 DE DE10110772A patent/DE10110772A1/de not_active Withdrawn
-
2002
- 2002-02-26 BR BR0207883-0A patent/BR0207883A/pt not_active IP Right Cessation
- 2002-02-26 MX MXPA03008045A patent/MXPA03008045A/es active IP Right Grant
- 2002-02-26 NZ NZ528621A patent/NZ528621A/en not_active IP Right Cessation
- 2002-02-26 WO PCT/EP2002/001988 patent/WO2002069945A2/de not_active Ceased
- 2002-02-26 CA CA2439763A patent/CA2439763C/en not_active Expired - Fee Related
- 2002-02-26 HU HU0400782A patent/HUP0400782A3/hu not_active Application Discontinuation
- 2002-02-26 JP JP2002569122A patent/JP2004521134A/ja active Pending
- 2002-02-26 AU AU2002257587A patent/AU2002257587B2/en not_active Ceased
- 2002-02-26 KR KR10-2003-7011716A patent/KR20030081501A/ko not_active Ceased
- 2002-02-26 PL PL02363078A patent/PL363078A1/xx not_active Application Discontinuation
- 2002-02-26 CN CNA02805346XA patent/CN1649588A/zh active Pending
- 2002-02-26 EP EP02727329A patent/EP1372649B1/de not_active Expired - Lifetime
- 2002-02-26 CZ CZ20032635A patent/CZ20032635A3/cs unknown
- 2002-02-26 EA EA200300929A patent/EA009989B1/ru not_active IP Right Cessation
- 2002-02-26 IL IL15732602A patent/IL157326A0/xx unknown
- 2002-03-06 AR ARP020100808A patent/AR034213A1/es not_active Application Discontinuation
- 2002-03-06 TW TW091104144A patent/TWI332833B/zh active
-
2003
- 2003-08-11 IL IL157326A patent/IL157326A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TWI332833B (en) | 2010-11-11 |
| EA009989B1 (ru) | 2008-04-28 |
| EA200300929A1 (ru) | 2004-04-29 |
| EP1372649B1 (de) | 2012-07-25 |
| DE10110772A1 (de) | 2002-09-12 |
| CA2439763C (en) | 2012-10-16 |
| IL157326A0 (en) | 2004-02-19 |
| KR20030081501A (ko) | 2003-10-17 |
| WO2002069945A3 (de) | 2003-01-30 |
| HUP0400782A3 (en) | 2012-09-28 |
| IL157326A (en) | 2011-12-29 |
| CN1649588A (zh) | 2005-08-03 |
| BR0207883A (pt) | 2004-07-27 |
| AU2002257587B2 (en) | 2007-05-10 |
| AR034213A1 (es) | 2004-02-04 |
| MXPA03008045A (es) | 2003-12-04 |
| EP1372649A2 (de) | 2004-01-02 |
| NZ528621A (en) | 2005-04-29 |
| CA2439763A1 (en) | 2002-09-12 |
| PL363078A1 (en) | 2004-11-15 |
| JP2004521134A (ja) | 2004-07-15 |
| WO2002069945A2 (de) | 2002-09-12 |
| HUP0400782A2 (hu) | 2004-07-28 |
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