CZ131092A3 - Process for preparing 4-demethylepipodophylotoxin-glucoside-4'-phosphates - Google Patents

Process for preparing 4-demethylepipodophylotoxin-glucoside-4'-phosphates Download PDF

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Publication number
CZ131092A3
CZ131092A3 CS921310A CS131092A CZ131092A3 CZ 131092 A3 CZ131092 A3 CZ 131092A3 CS 921310 A CS921310 A CS 921310A CS 131092 A CS131092 A CS 131092A CZ 131092 A3 CZ131092 A3 CZ 131092A3
Authority
CZ
Czechia
Prior art keywords
compound
benzyl
group
formula
groups
Prior art date
Application number
CS921310A
Other languages
Czech (cs)
English (en)
Inventor
Mark G Saulnier
John F Kadow
David R Langley
Min Min Tun
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CZ131092A3 publication Critical patent/CZ131092A3/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS921310A 1991-04-29 1992-04-29 Process for preparing 4-demethylepipodophylotoxin-glucoside-4'-phosphates CZ131092A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69398191A 1991-04-29 1991-04-29
US83495492A 1992-02-20 1992-02-20

Publications (1)

Publication Number Publication Date
CZ131092A3 true CZ131092A3 (en) 1993-01-13

Family

ID=27105281

Family Applications (1)

Application Number Title Priority Date Filing Date
CS921310A CZ131092A3 (en) 1991-04-29 1992-04-29 Process for preparing 4-demethylepipodophylotoxin-glucoside-4'-phosphates

Country Status (16)

Country Link
EP (1) EP0511563A1 (enrdf_load_stackoverflow)
JP (1) JPH05178880A (enrdf_load_stackoverflow)
KR (1) KR920019812A (enrdf_load_stackoverflow)
CN (1) CN1030141C (enrdf_load_stackoverflow)
AU (2) AU653788B2 (enrdf_load_stackoverflow)
CA (1) CA2062510A1 (enrdf_load_stackoverflow)
CZ (1) CZ131092A3 (enrdf_load_stackoverflow)
FI (1) FI921756L (enrdf_load_stackoverflow)
HU (3) HUT65255A (enrdf_load_stackoverflow)
IE (1) IE921285A1 (enrdf_load_stackoverflow)
IL (1) IL101188A (enrdf_load_stackoverflow)
MY (1) MY131083A (enrdf_load_stackoverflow)
NO (1) NO178826C (enrdf_load_stackoverflow)
NZ (1) NZ242059A (enrdf_load_stackoverflow)
SK (1) SK131092A3 (enrdf_load_stackoverflow)
TW (1) TW260671B (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3061476B2 (ja) * 1992-04-24 2000-07-10 日本化薬株式会社 エトポシド燐酸エステルの製造法
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフィロトキシン誘導体
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides

Also Published As

Publication number Publication date
NZ242059A (en) 1994-07-26
AU653788B2 (en) 1994-10-13
CA2062510A1 (en) 1992-10-30
HUT65255A (en) 1994-05-02
IE921285A1 (en) 1992-11-04
FI921756A7 (fi) 1992-10-30
JPH05178880A (ja) 1993-07-20
FI921756A0 (fi) 1992-04-21
IL101188A0 (en) 1992-11-15
EP0511563A1 (en) 1992-11-04
TW260671B (enrdf_load_stackoverflow) 1995-10-21
NO178826C (no) 1996-06-12
CN1066268A (zh) 1992-11-18
AU658343B2 (en) 1995-04-06
MY131083A (en) 2007-07-31
HU9201341D0 (en) 1992-07-28
HUT63428A (en) 1993-08-30
AU1288692A (en) 1992-11-05
HU9300731D0 (en) 1993-05-28
HUT63431A (en) 1993-08-30
FI921756L (fi) 1992-10-30
NO921363L (no) 1992-10-30
HU9300730D0 (en) 1993-05-28
NO921363D0 (no) 1992-04-08
AU6898194A (en) 1994-10-06
KR920019812A (ko) 1992-11-20
NO178826B (no) 1996-03-04
CN1030141C (zh) 1995-10-25
SK131092A3 (en) 1995-09-13
IL101188A (en) 1995-12-08

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