CY1831A - Antimigraine alkoxypyrimidine derivatives - Google Patents
Antimigraine alkoxypyrimidine derivativesInfo
- Publication number
- CY1831A CY1831A CY183195A CY183195A CY1831A CY 1831 A CY1831 A CY 1831A CY 183195 A CY183195 A CY 183195A CY 183195 A CY183195 A CY 183195A CY 1831 A CY1831 A CY 1831A
- Authority
- CY
- Cyprus
- Prior art keywords
- antimigraine
- alkoxypyrimidine
- derivatives
- alkoxypyrimidine derivatives
- indolylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54612290A | 1990-06-29 | 1990-06-29 | |
US68020891A | 1991-04-04 | 1991-04-04 | |
SG15595A SG15595G (en) | 1990-06-29 | 1995-01-30 | Antimigraine alkoxypyrimidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1831A true CY1831A (en) | 1995-12-01 |
Family
ID=27356028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY183195A CY1831A (en) | 1990-06-29 | 1995-12-01 | Antimigraine alkoxypyrimidine derivatives |
Country Status (15)
Country | Link |
---|---|
US (1) | US5300506A (fr) |
EP (1) | EP0464558B1 (fr) |
JP (1) | JPH04230378A (fr) |
AT (1) | ATE116312T1 (fr) |
AU (1) | AU643038B2 (fr) |
CA (1) | CA2043709C (fr) |
CY (1) | CY1831A (fr) |
DE (1) | DE69106237T2 (fr) |
DK (1) | DK0464558T3 (fr) |
ES (1) | ES2066278T3 (fr) |
FI (1) | FI101224B (fr) |
HK (1) | HK51995A (fr) |
IE (1) | IE66687B1 (fr) |
PT (1) | PT98115B (fr) |
SG (1) | SG15595G (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5077293A (en) * | 1990-06-29 | 1991-12-31 | Bristol-Myers Squibb Co. | 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines |
CA2084531A1 (fr) * | 1991-12-19 | 1993-06-20 | David W. Smith | Derives antimigraines 4-pyrimidinyle et pyridinyle d'indol-3yl-alkylpiperazines |
GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
GB9226610D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
US5521188A (en) * | 1993-09-16 | 1996-05-28 | Bristol-Myers Squibb Company | Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines |
CA2130078A1 (fr) * | 1993-09-16 | 1995-03-17 | Jonas A. Gylys | Derives cyclobutenediones de l'indolylakylpyridinyle et des pyrimidinylpiperazines ayant des proprietes antimigraineuses |
US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
ES2079323B1 (es) * | 1994-06-21 | 1996-10-16 | Vita Invest Sa | Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes. |
US5550239A (en) * | 1994-11-08 | 1996-08-27 | Bristol-Myers Squibb Company | Process for large-scale production of indolyl alkyl pyrimidinyl piperazine compounds |
GB9423682D0 (en) * | 1994-11-23 | 1995-01-11 | Merck Sharp & Dohme | Therapeutic agents |
GB9501865D0 (en) * | 1995-01-31 | 1995-03-22 | Merck Sharp & Dohme | Therapeutic agents |
US5618816A (en) * | 1995-03-02 | 1997-04-08 | Bristol-Myers Squibb Company | Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines |
AU6386196A (en) * | 1995-06-19 | 1997-01-15 | Eli Lilly And Company | Process for parallel synthesis of a non-peptide library |
EP0844996A1 (fr) * | 1995-08-07 | 1998-06-03 | MERCK SHARP & DOHME LTD. | Derives de 1-indolylpropyl-4-phenethylpiperazine substitues |
JPH09124643A (ja) * | 1995-08-14 | 1997-05-13 | Bristol Myers Squibb Co | 抗うつ作用を有する1−アリールアルキル−4−(アルコキシピリジニル)−又は4−(アルコキシピリミジニル)ピペラジン誘導体 |
AR004229A1 (es) * | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
GB9609374D0 (en) * | 1996-05-03 | 1996-07-10 | Merck Sharp & Dohme | Therapeutic agents |
US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
FR2799463B1 (fr) * | 1999-10-12 | 2004-04-16 | Adir | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent |
US20030096379A1 (en) * | 2001-03-28 | 2003-05-22 | Kilgore James L. | Method for producing tryptamine derivatives |
US6800637B2 (en) | 2002-09-12 | 2004-10-05 | Wyeth | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
EP1632491A1 (fr) * | 2004-08-30 | 2006-03-08 | Laboratorios Del Dr. Esteve, S.A. | composes indole substitues et leur utilisation comme modulateurs du recepteur 5-ht6 |
JP2009515834A (ja) * | 2006-08-29 | 2009-04-16 | テバ ファーマシューティカル インダストリーズ リミティド | 5−フェニル−1−トリチル−1h−テトラゾールの合成のための方法 |
EP2036888A1 (fr) * | 2007-09-17 | 2009-03-18 | Laboratorios del Dr. Esteve S.A. | Sulfonamides à substitution naphtyl |
MX2010009920A (es) * | 2008-03-14 | 2010-09-30 | Merck Patent Gmbh | Compuestos de azaindol para tratamiento de trastornos del sistema nervioso central. |
US20090281114A1 (en) * | 2008-05-08 | 2009-11-12 | Fabre-Kramer Pharmaceuticals, Inc. | Indolylalkyl derivatives of pyrimidinylpiperazine and metabolites thereof for treatment of anxiety, depression, and sexual dysfunction |
US9598401B2 (en) | 2013-07-29 | 2017-03-21 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB944443A (fr) * | 1959-09-25 | 1900-01-01 | ||
GB1189064A (en) * | 1967-05-01 | 1970-04-22 | Sterling Drug Inc | Indole Derivatives |
NL7103002A (fr) * | 1970-03-06 | 1971-09-08 | ||
GR79215B (fr) * | 1982-06-07 | 1984-10-22 | Glaxo Group Ltd | |
GB2162522B (en) * | 1984-08-01 | 1988-02-24 | Glaxo Group Ltd | An indole derivative |
GB8601959D0 (en) * | 1986-01-28 | 1986-03-05 | Glaxo Group Ltd | Indole derivatives |
US4954502A (en) * | 1988-06-10 | 1990-09-04 | Bristol-Myers Squibb Company | 1-indolyalkyl-4-(substituted-pyridinyl)piperazines |
FR2635104B1 (fr) * | 1988-08-03 | 1992-04-30 | Synthelabo | Derives d'indolone, leur preparation et leur application en therapeutique |
US5077293A (en) * | 1990-06-29 | 1991-12-31 | Bristol-Myers Squibb Co. | 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines |
-
1991
- 1991-05-31 CA CA002043709A patent/CA2043709C/fr not_active Expired - Fee Related
- 1991-06-24 AT AT91110376T patent/ATE116312T1/de not_active IP Right Cessation
- 1991-06-24 ES ES91110376T patent/ES2066278T3/es not_active Expired - Lifetime
- 1991-06-24 DE DE69106237T patent/DE69106237T2/de not_active Expired - Fee Related
- 1991-06-24 DK DK91110376.0T patent/DK0464558T3/da active
- 1991-06-24 EP EP91110376A patent/EP0464558B1/fr not_active Expired - Lifetime
- 1991-06-27 FI FI913142A patent/FI101224B/fi active
- 1991-06-27 PT PT98115A patent/PT98115B/pt not_active IP Right Cessation
- 1991-06-27 AU AU79416/91A patent/AU643038B2/en not_active Ceased
- 1991-06-28 IE IE228091A patent/IE66687B1/en not_active IP Right Cessation
- 1991-06-28 JP JP3183911A patent/JPH04230378A/ja active Pending
-
1992
- 1992-10-13 US US07/960,063 patent/US5300506A/en not_active Expired - Lifetime
-
1995
- 1995-01-30 SG SG15595A patent/SG15595G/en unknown
- 1995-04-06 HK HK51995A patent/HK51995A/xx not_active IP Right Cessation
- 1995-12-01 CY CY183195A patent/CY1831A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE69106237D1 (de) | 1995-02-09 |
PT98115A (pt) | 1992-03-31 |
HK51995A (en) | 1995-04-13 |
FI101224B1 (fi) | 1998-05-15 |
AU7941691A (en) | 1992-01-02 |
CA2043709C (fr) | 2002-01-22 |
PT98115B (pt) | 1998-12-31 |
IE66687B1 (en) | 1996-01-24 |
EP0464558A1 (fr) | 1992-01-08 |
FI913142A (fi) | 1991-12-30 |
IE912280A1 (en) | 1992-01-01 |
EP0464558B1 (fr) | 1994-12-28 |
ATE116312T1 (de) | 1995-01-15 |
DE69106237T2 (de) | 1995-05-11 |
FI913142A0 (fi) | 1991-06-27 |
SG15595G (en) | 1995-06-16 |
JPH04230378A (ja) | 1992-08-19 |
DK0464558T3 (da) | 1995-03-13 |
CA2043709A1 (fr) | 1991-12-30 |
US5300506A (en) | 1994-04-05 |
AU643038B2 (en) | 1993-11-04 |
FI101224B (fi) | 1998-05-15 |
ES2066278T3 (es) | 1995-03-01 |
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