CY1831A - Antimigraine alkoxypyrimidine derivatives - Google Patents

Antimigraine alkoxypyrimidine derivatives

Info

Publication number
CY1831A
CY1831A CY183195A CY183195A CY1831A CY 1831 A CY1831 A CY 1831A CY 183195 A CY183195 A CY 183195A CY 183195 A CY183195 A CY 183195A CY 1831 A CY1831 A CY 1831A
Authority
CY
Cyprus
Prior art keywords
antimigraine
alkoxypyrimidine
derivatives
alkoxypyrimidine derivatives
indolylalkyl
Prior art date
Application number
CY183195A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CY1831A publication Critical patent/CY1831A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY183195A 1990-06-29 1995-12-01 Antimigraine alkoxypyrimidine derivatives CY1831A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54612290A 1990-06-29 1990-06-29
US68020891A 1991-04-04 1991-04-04
SG15595A SG15595G (en) 1990-06-29 1995-01-30 Antimigraine alkoxypyrimidine derivatives

Publications (1)

Publication Number Publication Date
CY1831A true CY1831A (en) 1995-12-01

Family

ID=27356028

Family Applications (1)

Application Number Title Priority Date Filing Date
CY183195A CY1831A (en) 1990-06-29 1995-12-01 Antimigraine alkoxypyrimidine derivatives

Country Status (15)

Country Link
US (1) US5300506A (xx)
EP (1) EP0464558B1 (xx)
JP (1) JPH04230378A (xx)
AT (1) ATE116312T1 (xx)
AU (1) AU643038B2 (xx)
CA (1) CA2043709C (xx)
CY (1) CY1831A (xx)
DE (1) DE69106237T2 (xx)
DK (1) DK0464558T3 (xx)
ES (1) ES2066278T3 (xx)
FI (1) FI101224B1 (xx)
HK (1) HK51995A (xx)
IE (1) IE66687B1 (xx)
PT (1) PT98115B (xx)
SG (1) SG15595G (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077293A (en) * 1990-06-29 1991-12-31 Bristol-Myers Squibb Co. 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9226610D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
CA2130078A1 (en) * 1993-09-16 1995-03-17 Jonas A. Gylys Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
US5521188A (en) * 1993-09-16 1996-05-28 Bristol-Myers Squibb Company Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
ES2079323B1 (es) * 1994-06-21 1996-10-16 Vita Invest Sa Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
US5550239A (en) * 1994-11-08 1996-08-27 Bristol-Myers Squibb Company Process for large-scale production of indolyl alkyl pyrimidinyl piperazine compounds
GB9423682D0 (en) * 1994-11-23 1995-01-11 Merck Sharp & Dohme Therapeutic agents
GB9501865D0 (en) * 1995-01-31 1995-03-22 Merck Sharp & Dohme Therapeutic agents
US5618816A (en) * 1995-03-02 1997-04-08 Bristol-Myers Squibb Company Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines
AU6386196A (en) * 1995-06-19 1997-01-15 Eli Lilly And Company Process for parallel synthesis of a non-peptide library
WO1997006159A1 (en) * 1995-08-07 1997-02-20 Merck Sharp & Dohme Limited Substituted 1-indolylpropyl-4-phenethylpiperazine derivatives
JPH09124643A (ja) * 1995-08-14 1997-05-13 Bristol Myers Squibb Co 抗うつ作用を有する１−アリールアルキル−４−（アルコキシピリジニル）−又は４−（アルコキシピリミジニル）ピペラジン誘導体
AR004229A1 (es) * 1995-11-06 1998-11-04 Wyeth Corp Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
GB9609374D0 (en) * 1996-05-03 1996-07-10 Merck Sharp & Dohme Therapeutic agents
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
FR2799463B1 (fr) * 1999-10-12 2004-04-16 Adir Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent
US20030096379A1 (en) * 2001-03-28 2003-05-22 Kilgore James L. Method for producing tryptamine derivatives
US6800637B2 (en) 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
EP1632491A1 (en) * 2004-08-30 2006-03-08 Laboratorios Del Dr. Esteve, S.A. Substituted indole compounds and their use as 5-HT6 receptor modulators
EP1931648A2 (en) * 2006-08-29 2008-06-18 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of 5-phenyl -1 trityl-1h-tetrazole
EP2036888A1 (en) * 2007-09-17 2009-03-18 Laboratorios del Dr. Esteve S.A. Naphthyl-substituted sulfonamides
CA2718138A1 (en) * 2008-03-14 2009-09-17 Timo Heinrich Azaindole compounds for treatment of central nervous system disorders
US20090281114A1 (en) * 2008-05-08 2009-11-12 Fabre-Kramer Pharmaceuticals, Inc. Indolylalkyl derivatives of pyrimidinylpiperazine and metabolites thereof for treatment of anxiety, depression, and sexual dysfunction
CN104337812B (zh) 2013-07-29 2018-09-14 广东东阳光药业有限公司 取代的杂芳基化合物及其使用方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB944443A (xx) * 1959-09-25 1900-01-01
GB1189064A (en) * 1967-05-01 1970-04-22 Sterling Drug Inc Indole Derivatives
DE2110534C3 (de) * 1970-03-06 1979-03-08 Sumitomo Chemical Co., Ltd., Osaka (Japan) γ-Piperazinobutyrophenonderivate, Verfahren zu ihrer Herstellung und Arzneipräparate
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8601959D0 (en) * 1986-01-28 1986-03-05 Glaxo Group Ltd Indole derivatives
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
FR2635104B1 (fr) * 1988-08-03 1992-04-30 Synthelabo Derives d'indolone, leur preparation et leur application en therapeutique
US5077293A (en) * 1990-06-29 1991-12-31 Bristol-Myers Squibb Co. 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines

Also Published As

Publication number Publication date
AU643038B2 (en) 1993-11-04
PT98115B (pt) 1998-12-31
FI101224B (fi) 1998-05-15
ATE116312T1 (de) 1995-01-15
DK0464558T3 (da) 1995-03-13
EP0464558B1 (en) 1994-12-28
IE66687B1 (en) 1996-01-24
FI101224B1 (fi) 1998-05-15
CA2043709A1 (en) 1991-12-30
CA2043709C (en) 2002-01-22
JPH04230378A (ja) 1992-08-19
PT98115A (pt) 1992-03-31
FI913142A0 (fi) 1991-06-27
DE69106237T2 (de) 1995-05-11
DE69106237D1 (de) 1995-02-09
HK51995A (en) 1995-04-13
US5300506A (en) 1994-04-05
EP0464558A1 (en) 1992-01-08
SG15595G (en) 1995-06-16
IE912280A1 (en) 1992-01-01
AU7941691A (en) 1992-01-02
FI913142A (fi) 1991-12-30
ES2066278T3 (es) 1995-03-01

Similar Documents

Publication Publication Date Title
CY1831A (en) Antimigraine alkoxypyrimidine derivatives
MY103352A (en) Piperazinyl-heterocyclic compounds
SI0955295T1 (en) Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines
HU9302384D0 (en) 2,4-diamino-quinazoline derivatives and medical preparatives containing them
NO990542L (no) K-252a-derivater og anvendelse av K-252a-derivater
DE69231123D1 (de) Konjugaten von Zell-bindender Mittel und Derivaten von CC-1065
PH30988A (en) Antimigraine-4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines.
EP0276536A3 (en) Use of buspirone for the improvement of short term memory
ZA93958B (en) Piperazine and piperidine derivatives and their use in therapy
EP0278173A3 (en) Use of heterocyclic derivatives in the treatment of depressions
AU3959193A (en) Heterocyclic compounds and their use in the treatment of type II-diabetes
NZ237309A (en) 1-(2-(4-morpholino)ethyl)-3-(arylcarbonyl)-indole derivatives and pharmaceutical compositions
DE59107445D1 (de) Kombination von Arbeitsgerät und höhenverstellbare Versorgungseinheit
HU9501801D0 (en) Lactame-compounds as pharmaceutical active component
AU658656B2 (en) 4-phenylmethylpiperazine derivatives and their use as antiallergic and antihistaminic agents
MY103210A (en) Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds.
HU913989D0 (en) Anti-herpetic castanospermin esthers
GR3015716T3 (en) Use of buspirone in sleep apneas.
EP0437026A3 (en) Use of tandospirone in the treatment of depression
AU4787593A (en) Heterocyclic derivatives useful in the treatment of cardiovascular diseases
ATE70181T1 (de) Verwendung von oxochinazolinderivaten bei der behandlung von hyperurikaemie.
HUT46192A (en) Fungicides and bactericides comprising pyrimidine derivatives as active ingredient and process for producing the active ingredient
AU4096689A (en) The use of lactam derivatives in the treatment of addiction
AU4096889A (en) The use of lactam derivatives in the treatment of depression
GR900100214A (el) Ασφαλιστική παροχή αίματος και παραγώγων αίματος.