CY1124494T1 - Μεθοδοι για τον προσδιορισμο του κλασματος εμβρυικων νουκλεϊκων οξεων σε μητρικα δειγματα - Google Patents

Μεθοδοι για τον προσδιορισμο του κλασματος εμβρυικων νουκλεϊκων οξεων σε μητρικα δειγματα

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Publication number
CY1124494T1
CY1124494T1 CY20211100424T CY211100424T CY1124494T1 CY 1124494 T1 CY1124494 T1 CY 1124494T1 CY 20211100424 T CY20211100424 T CY 20211100424T CY 211100424 T CY211100424 T CY 211100424T CY 1124494 T1 CY1124494 T1 CY 1124494T1
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CY
Cyprus
Prior art keywords
nucleic acids
fraction
methods
determination
fetal nucleic
Prior art date
Application number
CY20211100424T
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English (en)
Inventor
Richard P. Rava
Yue-Jen Chuu
Manjula CHINNAPPA
David A. COMSTOCK
Gabrielle HEILEK
Michael Hunkapiller
Original Assignee
Verinata Health, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44307118&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1124494(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2010/058606 external-priority patent/WO2011090556A1/en
Application filed by Verinata Health, Inc. filed Critical Verinata Health, Inc.
Publication of CY1124494T1 publication Critical patent/CY1124494T1/el

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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6869—Methods for sequencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C40—COMBINATORIAL TECHNOLOGY
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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    • C12Q2545/00—Reactions characterised by their quantitative nature
    • C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
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  • Epidemiology (AREA)
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Abstract

Η εφεύρεση παρέχει συνθέσεις και μεθόδους για τον προσδιορισμό του κλάσματος εμβρυϊκών νουκλεϊκών οξέων εντός μητρικού δείγματος περιλαμβάνοντος μείγμα εμβρυϊκών και μητρικών νουκλεϊκών οξέων. Το κλάσμα εμβρυϊκών νουκλεϊκών οξέων μπορεί να χρησιμοποιηθεί στον προσδιορισμό της παρουσίας ή μη εμβρυικής ανευπλοειδίας.
CY20211100424T 2010-01-19 2021-05-17 Μεθοδοι για τον προσδιορισμο του κλασματος εμβρυικων νουκλεϊκων οξεων σε μητρικα δειγματα CY1124494T1 (el)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US29635810P 2010-01-19 2010-01-19
US36083710P 2010-07-01 2010-07-01
US40701710P 2010-10-26 2010-10-26
US45584910P 2010-10-26 2010-10-26
EP15181244.3A EP3006573B1 (en) 2010-01-19 2010-12-01 Methods for determining fraction of fetal nucleic acids in maternal samples
PCT/US2010/058606 WO2011090556A1 (en) 2010-01-19 2010-12-01 Methods for determining fraction of fetal nucleic acid in maternal samples
EP10844163.5A EP2513339B1 (en) 2010-01-19 2010-12-01 Methods for determining fraction of fetal nucleic acid in maternal samples

Publications (1)

Publication Number Publication Date
CY1124494T1 true CY1124494T1 (el) 2022-07-22

Family

ID=44307118

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CY20211100424T CY1124494T1 (el) 2010-01-19 2021-05-17 Μεθοδοι για τον προσδιορισμο του κλασματος εμβρυικων νουκλεϊκων οξεων σε μητρικα δειγματα

Country Status (12)

Country Link
US (12) US9657342B2 (el)
EP (13) EP2848704B1 (el)
AU (4) AU2010343279B2 (el)
CA (4) CA2785718C (el)
CY (1) CY1124494T1 (el)
DK (6) DK3492601T3 (el)
ES (6) ES2534986T3 (el)
GB (5) GB2479476B (el)
HK (6) HK1160185A1 (el)
PL (4) PL3260555T3 (el)
TR (1) TR201807917T4 (el)
WO (3) WO2011090558A1 (el)

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