CY1123856T1 - Αντικαρκινικες συνθεσεις - Google Patents

Αντικαρκινικες συνθεσεις

Info

Publication number
CY1123856T1
CY1123856T1 CY20211100068T CY211100068T CY1123856T1 CY 1123856 T1 CY1123856 T1 CY 1123856T1 CY 20211100068 T CY20211100068 T CY 20211100068T CY 211100068 T CY211100068 T CY 211100068T CY 1123856 T1 CY1123856 T1 CY 1123856T1
Authority
CY
Cyprus
Prior art keywords
arn
prostate cancer
meth
poly
acrylate copolymer
Prior art date
Application number
CY20211100068T
Other languages
Greek (el)
English (en)
Inventor
Geert Verreck
Original Assignee
Aragon Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52006905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1123856(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aragon Pharmaceuticals, Inc. filed Critical Aragon Pharmaceuticals, Inc.
Publication of CY1123856T1 publication Critical patent/CY1123856T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CY20211100068T 2014-12-05 2021-01-27 Αντικαρκινικες συνθεσεις CY1123856T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14196591 2014-12-05
PCT/US2015/063667 WO2016090101A1 (en) 2014-12-05 2015-12-03 Anticancer compositions

Publications (1)

Publication Number Publication Date
CY1123856T1 true CY1123856T1 (el) 2022-05-27

Family

ID=52006905

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100068T CY1123856T1 (el) 2014-12-05 2021-01-27 Αντικαρκινικες συνθεσεις

Country Status (31)

Country Link
US (3) US20170360707A1 (enExample)
EP (2) EP3226842B1 (enExample)
JP (1) JP6767368B2 (enExample)
KR (1) KR102348325B1 (enExample)
CN (2) CN106999430A (enExample)
AR (1) AR102924A1 (enExample)
AU (1) AU2015358493B2 (enExample)
CA (1) CA2969661C (enExample)
CL (1) CL2017001372A1 (enExample)
CO (1) CO2017005573A2 (enExample)
CR (1) CR20170217A (enExample)
CY (1) CY1123856T1 (enExample)
DK (1) DK3226842T3 (enExample)
EA (1) EA035988B1 (enExample)
ES (2) ES3021508T3 (enExample)
HR (1) HRP20201902T1 (enExample)
HU (1) HUE051888T2 (enExample)
IL (1) IL252324B (enExample)
LT (1) LT3226842T (enExample)
MA (2) MA55404A (enExample)
MD (1) MD3226842T2 (enExample)
MX (1) MX384382B (enExample)
NI (1) NI201700069A (enExample)
PL (1) PL3226842T3 (enExample)
PT (1) PT3226842T (enExample)
RS (1) RS61466B1 (enExample)
SG (1) SG11201704264UA (enExample)
SI (1) SI3226842T1 (enExample)
TW (1) TWI683662B (enExample)
UA (1) UA121123C2 (enExample)
WO (1) WO2016090101A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014052237A1 (en) 2012-09-26 2014-04-03 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
CN114886852A (zh) 2014-12-05 2022-08-12 阿拉贡药品公司 抗癌组合物
RS62421B1 (sr) 2014-12-05 2021-10-29 Aragon Pharmaceuticals Inc Anti-kancerogeni sastavi
KR20240096623A (ko) 2017-10-16 2024-06-26 아라곤 파마슈티컬스, 인코포레이티드 비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐
EP3773509B1 (en) * 2018-04-06 2023-11-01 Capsugel Belgium NV Spray drying process for low aspect ratio particles comprising poly[(methyl methacrylate)-co-(methacrylic acid)]
WO2020144649A1 (en) 2019-01-10 2020-07-16 Aragon Pharmaceuticals, Inc. Pharmaceutical composition comprising enzalutamide dispersed in apple sauce
KR20210122275A (ko) 2019-01-30 2021-10-08 얀센 파마슈티카 엔.브이. 분자 아형에 기초하여 전립선암을 치료하는 방법
SG11202107712SA (en) 2019-01-30 2021-08-30 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of metastatic castration-sensitive prostate cancer
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
DK4054572T3 (da) 2019-11-04 2026-08-03 Aragon Pharmaceuticals Inc Apalutanid til behandling af ikke-metastatisk kastrationsresistent prostatacancer hos subjekter med svært nedsat leverfunktion
WO2021245285A1 (en) 2020-06-05 2021-12-09 Janssen Pharmaceutica Nv Methods of treating prostate cancer based on molecular subtypes
WO2022049523A1 (en) 2020-09-04 2022-03-10 Aragon Pharmaceuticals, Inc. Methods for treating prostate cancer
WO2022195407A1 (en) 2021-03-19 2022-09-22 Aragon Pharmaceuticals, Inc. Methods for treating prostate cancer
WO2023152611A1 (en) 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer
WO2023209555A1 (en) 2022-04-26 2023-11-02 Aragon Pharmaceuticals, Inc. Approved drug products and methods for treating prostate cancer
JP2026515598A (ja) 2023-03-16 2026-05-19 バイエル・コンシューマー・ケア・アクチェンゲゼルシャフト ホルモン感受性前立腺がんの生化学的再発を有する患者の処置のためのアンドロゲン受容体アンタゴニスト
WO2026052846A1 (en) 2024-09-09 2026-03-12 Synthon B.V. Pharmaceutical formulation comprising apalutamide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20032647A3 (cs) 2001-04-02 2004-09-15 Astrazeneca Ab Pevná farmaceutická kompozice obsahující 4-kyanotrifluor-3-(4-fluorfenylsulfonyl)-2-hydroxy-2-methylpropiono-m-toluidin a PVP
JPWO2003077827A1 (ja) * 2002-03-19 2005-07-14 日本新薬株式会社 医薬固体分散体の製造方法
JP2007518670A (ja) * 2003-12-15 2007-07-12 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ 苦味のある薬物、及びpH感受性ポリマーを含む風味マスクされた医薬組成物
BRPI0709771B1 (pt) * 2006-03-27 2022-01-25 The Regents Of The University Of California Composto e composição farmacêutica
EP3124481B1 (en) * 2010-02-16 2018-03-28 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
CA2839301C (en) * 2011-06-15 2021-02-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
WO2013152342A1 (en) 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Anti-cancer mtor inhibitor and anti-androgen combination
UA123142C2 (uk) 2012-06-07 2021-02-24 Арагон Фармасьютікалз, Інк. Кристалічні форми модулятора андрогенного рецептора
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
TWI673051B (zh) * 2012-09-11 2019-10-01 美商梅維森前列腺療法有限責任公司 恩雜魯它脈(enzalutamide)之調和物
WO2014052237A1 (en) * 2012-09-26 2014-04-03 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
EP2945628B1 (en) * 2013-01-15 2020-04-15 Aragon Pharmaceuticals, Inc. Androgen receptor modulator in combination with abiraterone acetate and prednisone for treating prostate cancer
NZ708272A (en) * 2013-01-22 2020-07-31 Hoffmann La Roche Pharmaceutical composition with improved bioavailability
WO2014167428A2 (en) 2013-04-10 2014-10-16 Shilpa Medicare Limited Amorphous 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-n-methylbenzamide
KR20160058774A (ko) * 2013-08-12 2016-05-25 토카이 파마슈티컬, 아이엔씨. 안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
CN106102716A (zh) * 2014-02-05 2016-11-09 斯洛文尼亚莱柯制药股份有限公司 雄激素受体拮抗剂的固体药物组合物

Also Published As

Publication number Publication date
MX384382B (es) 2025-03-14
US20220151931A1 (en) 2022-05-19
DK3226842T3 (da) 2021-01-25
CN115837010B (zh) 2025-03-14
KR20170086657A (ko) 2017-07-26
EA201791252A1 (ru) 2017-10-31
SI3226842T1 (sl) 2021-04-30
KR102348325B1 (ko) 2022-01-06
NI201700069A (es) 2017-10-31
MA41108A (fr) 2016-06-09
CO2017005573A2 (es) 2017-09-29
TWI683662B (zh) 2020-02-01
AR102924A1 (es) 2017-04-05
EP3842034B1 (en) 2025-02-12
EP3226842A1 (en) 2017-10-11
BR112017011787A2 (pt) 2017-12-26
MA55404A (fr) 2022-02-02
ES2839128T3 (es) 2021-07-05
CL2017001372A1 (es) 2018-01-05
HUE051888T2 (hu) 2021-03-29
CA2969661A1 (en) 2016-06-09
JP6767368B2 (ja) 2020-10-14
EA035988B1 (ru) 2020-09-09
RS61466B1 (sr) 2021-03-31
AU2015358493A1 (en) 2017-06-08
AU2015358493B2 (en) 2021-05-06
UA121123C2 (uk) 2020-04-10
EP3226842B1 (en) 2020-11-25
IL252324A0 (en) 2017-07-31
SG11201704264UA (en) 2017-06-29
ES3021508T3 (en) 2025-05-27
CR20170217A (es) 2017-08-30
MD3226842T2 (ro) 2021-03-31
MA41108B1 (fr) 2021-03-31
HRP20201902T1 (hr) 2021-07-23
US20170360707A1 (en) 2017-12-21
MX2017007201A (es) 2018-01-30
IL252324B (en) 2021-10-31
WO2016090101A1 (en) 2016-06-09
PL3226842T3 (pl) 2021-07-12
JP2017536401A (ja) 2017-12-07
US20240293321A1 (en) 2024-09-05
TW201632187A (zh) 2016-09-16
LT3226842T (lt) 2021-03-25
CA2969661C (en) 2023-04-25
EP3842034A1 (en) 2021-06-30
CN115837010A (zh) 2023-03-24
CN106999430A (zh) 2017-08-01
PT3226842T (pt) 2020-12-23

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