PL3226842T3 - Kompozycje przeciwnowotworowe - Google Patents

Kompozycje przeciwnowotworowe

Info

Publication number
PL3226842T3
PL3226842T3 PL15817642T PL15817642T PL3226842T3 PL 3226842 T3 PL3226842 T3 PL 3226842T3 PL 15817642 T PL15817642 T PL 15817642T PL 15817642 T PL15817642 T PL 15817642T PL 3226842 T3 PL3226842 T3 PL 3226842T3
Authority
PL
Poland
Prior art keywords
anticancer compositions
anticancer
compositions
Prior art date
Application number
PL15817642T
Other languages
English (en)
Polish (pl)
Inventor
Geert Verreck
Original Assignee
Aragon Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52006905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3226842(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aragon Pharmaceuticals, Inc. filed Critical Aragon Pharmaceuticals, Inc.
Publication of PL3226842T3 publication Critical patent/PL3226842T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL15817642T 2014-12-05 2015-12-03 Kompozycje przeciwnowotworowe PL3226842T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14196591 2014-12-05
PCT/US2015/063667 WO2016090101A1 (en) 2014-12-05 2015-12-03 Anticancer compositions
EP15817642.0A EP3226842B1 (en) 2014-12-05 2015-12-03 Anticancer compositions

Publications (1)

Publication Number Publication Date
PL3226842T3 true PL3226842T3 (pl) 2021-07-12

Family

ID=52006905

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15817642T PL3226842T3 (pl) 2014-12-05 2015-12-03 Kompozycje przeciwnowotworowe

Country Status (31)

Country Link
US (3) US20170360707A1 (enExample)
EP (2) EP3226842B1 (enExample)
JP (1) JP6767368B2 (enExample)
KR (1) KR102348325B1 (enExample)
CN (2) CN115837010B (enExample)
AR (1) AR102924A1 (enExample)
AU (1) AU2015358493B2 (enExample)
CA (1) CA2969661C (enExample)
CL (1) CL2017001372A1 (enExample)
CO (1) CO2017005573A2 (enExample)
CR (1) CR20170217A (enExample)
CY (1) CY1123856T1 (enExample)
DK (1) DK3226842T3 (enExample)
EA (1) EA035988B1 (enExample)
ES (2) ES3021508T3 (enExample)
HR (1) HRP20201902T1 (enExample)
HU (1) HUE051888T2 (enExample)
IL (1) IL252324B (enExample)
LT (1) LT3226842T (enExample)
MA (2) MA41108B1 (enExample)
MD (1) MD3226842T2 (enExample)
MX (1) MX384382B (enExample)
NI (1) NI201700069A (enExample)
PL (1) PL3226842T3 (enExample)
PT (1) PT3226842T (enExample)
RS (1) RS61466B1 (enExample)
SG (1) SG11201704264UA (enExample)
SI (1) SI3226842T1 (enExample)
TW (1) TWI683662B (enExample)
UA (1) UA121123C2 (enExample)
WO (1) WO2016090101A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL312316A (en) 2012-09-26 2024-06-01 Aragon Pharmaceuticals Inc Antiandrogens for the treatment of castration-resistant prostate cancer without metastases
CN106999431B (zh) 2014-12-05 2022-03-04 阿拉贡药品公司 抗癌组合物
AU2015358497B2 (en) 2014-12-05 2021-04-29 Aragon Pharmaceuticals, Inc. Anticancer compositions
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال
US11708463B2 (en) * 2018-04-06 2023-07-25 Capsugel Belgium Nv Spray drying process for low aspect ratio particles comprising poly[(methyl methacrylate)-co-(methacrylic acid)]
WO2020144647A1 (en) 2019-01-10 2020-07-16 Aragon Pharmaceuticals, Inc. Pharmaceutical composition comprising apalutamide dispersed in apple sauce
TWI840496B (zh) 2019-01-30 2024-05-01 美商艾瑞岡醫藥公司 用於治療轉移性去勢敏感性前列腺癌之抗雄性激素
EP3918607A1 (en) 2019-01-30 2021-12-08 Janssen Pharmaceutica NV Methods of treating prostate cancer based on molecular subtypes
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
EP4054572A1 (en) 2019-11-04 2022-09-14 Aragon Pharmaceuticals, Inc. Androgen receptor inhibitors for the treatment of non-metastatic castration-resistant prostate cancer in subjects with severe hepatic impairment
WO2021245285A1 (en) 2020-06-05 2021-12-09 Janssen Pharmaceutica Nv Methods of treating prostate cancer based on molecular subtypes
TW202228794A (zh) 2020-09-04 2022-08-01 美商艾瑞岡醫藥公司 用於治療前列腺癌之方法
WO2022195407A1 (en) 2021-03-19 2022-09-22 Aragon Pharmaceuticals, Inc. Methods for treating prostate cancer
WO2023152611A1 (en) 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer
WO2023209555A1 (en) 2022-04-26 2023-11-02 Aragon Pharmaceuticals, Inc. Approved drug products and methods for treating prostate cancer
WO2024189186A1 (en) 2023-03-16 2024-09-19 Bayer Consumer Care Ag Androgen receptor antagonists for the treatment of patients with biochemical recurrence of hormone sensitive prostate cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2261655T3 (es) 2001-04-02 2006-11-16 Astrazeneca Ab Composicion farmaceutica solida que comprende 4'-ciano-trifluoro-3-(4-fluorofenilsulfonil)-2-hidroxi-2-metilpropiono-m-toluiduro y pvp.
JPWO2003077827A1 (ja) * 2002-03-19 2005-07-14 日本新薬株式会社 医薬固体分散体の製造方法
CA2549572A1 (en) * 2003-12-15 2005-06-23 Council Of Scientific & Industrial Research Taste masked pharmaceutical compositions comprising bitter drug and ph sensitive polymer
DK2656842T3 (en) * 2006-03-27 2016-11-07 Univ California Androgen receptor MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND androgen receptor-ASSOCIATED DISEASES
AU2011218173C1 (en) * 2010-02-16 2015-04-16 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
US10071945B2 (en) * 2011-06-15 2018-09-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
WO2013152342A1 (en) * 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Anti-cancer mtor inhibitor and anti-androgen combination
NZ702203A (en) 2012-06-07 2016-09-30 Aragon Pharmaceuticals Inc Crystalline forms of an androgen receptor modulator
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
PL3725778T3 (pl) * 2012-09-11 2021-12-20 Medivation Prostate Therapeutics Llc Preparaty enzalutamidu
IL312316A (en) * 2012-09-26 2024-06-01 Aragon Pharmaceuticals Inc Antiandrogens for the treatment of castration-resistant prostate cancer without metastases
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
CA2892025C (en) * 2013-01-22 2022-02-15 F. Hoffmann-La Roche Ag Solid dispersions comprising 4-{[(2r, 3s, 4r, 5s)-4-(4-chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3- methoxy -benzoic acid and pharmaceutical compositions comprising same with improved bioavailability
WO2014167428A2 (en) 2013-04-10 2014-10-16 Shilpa Medicare Limited Amorphous 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-n-methylbenzamide
EP3033088A4 (en) * 2013-08-12 2017-03-08 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
CN112402360A (zh) * 2014-02-05 2021-02-26 斯洛文尼亚莱柯制药股份有限公司 雄激素受体拮抗剂的固体药物组合物

Also Published As

Publication number Publication date
MD3226842T2 (ro) 2021-03-31
CO2017005573A2 (es) 2017-09-29
US20170360707A1 (en) 2017-12-21
AU2015358493B2 (en) 2021-05-06
KR102348325B1 (ko) 2022-01-06
WO2016090101A1 (en) 2016-06-09
EA035988B1 (ru) 2020-09-09
TWI683662B (zh) 2020-02-01
US20240293321A1 (en) 2024-09-05
CL2017001372A1 (es) 2018-01-05
AU2015358493A1 (en) 2017-06-08
IL252324B (en) 2021-10-31
MA41108A (fr) 2016-06-09
EP3226842A1 (en) 2017-10-11
NI201700069A (es) 2017-10-31
PT3226842T (pt) 2020-12-23
HRP20201902T1 (hr) 2021-07-23
BR112017011787A2 (pt) 2017-12-26
EA201791252A1 (ru) 2017-10-31
RS61466B1 (sr) 2021-03-31
IL252324A0 (en) 2017-07-31
MA41108B1 (fr) 2021-03-31
JP6767368B2 (ja) 2020-10-14
HUE051888T2 (hu) 2021-03-29
CA2969661A1 (en) 2016-06-09
MX2017007201A (es) 2018-01-30
EP3842034A1 (en) 2021-06-30
KR20170086657A (ko) 2017-07-26
CN115837010A (zh) 2023-03-24
ES3021508T3 (en) 2025-05-27
CN115837010B (zh) 2025-03-14
CR20170217A (es) 2017-08-30
SI3226842T1 (sl) 2021-04-30
JP2017536401A (ja) 2017-12-07
CN106999430A (zh) 2017-08-01
CY1123856T1 (el) 2022-05-27
MA55404A (fr) 2022-02-02
AR102924A1 (es) 2017-04-05
EP3842034B1 (en) 2025-02-12
SG11201704264UA (en) 2017-06-29
US20220151931A1 (en) 2022-05-19
ES2839128T3 (es) 2021-07-05
MX384382B (es) 2025-03-14
TW201632187A (zh) 2016-09-16
LT3226842T (lt) 2021-03-25
DK3226842T3 (da) 2021-01-25
EP3226842B1 (en) 2020-11-25
CA2969661C (en) 2023-04-25
UA121123C2 (uk) 2020-04-10

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