CY1122604T1 - Αγγειοτασινη ii σε συνδυασμο για την αντιμετωπιση υποτασης - Google Patents
Αγγειοτασινη ii σε συνδυασμο για την αντιμετωπιση υποτασηςInfo
- Publication number
- CY1122604T1 CY1122604T1 CY20201100026T CY201100026T CY1122604T1 CY 1122604 T1 CY1122604 T1 CY 1122604T1 CY 20201100026 T CY20201100026 T CY 20201100026T CY 201100026 T CY201100026 T CY 201100026T CY 1122604 T1 CY1122604 T1 CY 1122604T1
- Authority
- CY
- Cyprus
- Prior art keywords
- mcg
- dose
- equivalent
- angiotasin
- hypotension
- Prior art date
Links
- 208000001953 Hypotension Diseases 0.000 title 1
- 230000036543 hypotension Effects 0.000 title 1
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 3
- 229960002748 norepinephrine Drugs 0.000 abstract 3
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 3
- 150000003943 catecholamines Chemical class 0.000 abstract 2
- 102000005862 Angiotensin II Human genes 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 230000004872 arterial blood pressure Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917576P | 2013-12-18 | 2013-12-18 | |
| US201461955706P | 2014-03-19 | 2014-03-19 | |
| PCT/US2014/071186 WO2015095535A1 (en) | 2013-12-18 | 2014-12-18 | Angiotensin ii alone or in combination for the treatment of hypotension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1122604T1 true CY1122604T1 (el) | 2021-03-12 |
Family
ID=53367119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100026T CY1122604T1 (el) | 2013-12-18 | 2020-01-13 | Αγγειοτασινη ii σε συνδυασμο για την αντιμετωπιση υποτασης |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US9220745B2 (enExample) |
| EP (2) | EP2986308B1 (enExample) |
| JP (4) | JP6824739B2 (enExample) |
| KR (4) | KR102399383B1 (enExample) |
| CN (4) | CN106061493A (enExample) |
| AU (3) | AU2014364528C1 (enExample) |
| BR (1) | BR112016013961A2 (enExample) |
| CA (1) | CA2933601A1 (enExample) |
| CY (1) | CY1122604T1 (enExample) |
| DK (2) | DK3607962T3 (enExample) |
| EA (1) | EA037823B1 (enExample) |
| ES (1) | ES2771749T3 (enExample) |
| FI (1) | FI3607962T3 (enExample) |
| HR (1) | HRP20200009T1 (enExample) |
| HU (1) | HUE047062T2 (enExample) |
| IL (1) | IL246162B (enExample) |
| LT (2) | LT3607962T (enExample) |
| MX (2) | MX380968B (enExample) |
| NZ (1) | NZ721089A (enExample) |
| PL (1) | PL2986308T3 (enExample) |
| PT (2) | PT3607962T (enExample) |
| RS (1) | RS59804B1 (enExample) |
| SI (1) | SI2986308T1 (enExample) |
| SM (2) | SMT202000018T1 (enExample) |
| WO (1) | WO2015095535A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| US9220745B2 (en) | 2013-12-18 | 2015-12-29 | The George Washington University, a Congressionally Not-for-Profit Corporation | Angiotensin II alone or in combination for the treatment of hypotension |
| KR20170026486A (ko) * | 2014-07-08 | 2017-03-08 | 라 졸라 파마슈티칼 컴파니 | 저혈압 치료 방법 |
| US9919022B2 (en) | 2015-03-20 | 2018-03-20 | Arthur J. ATKINSON, JR. | Use of angiotensin II (AII) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps |
| BR112018013847A2 (pt) | 2016-01-07 | 2018-12-18 | La Jolla Pharma Co | métodos para administrar a angiotensina ii |
| WO2017120440A1 (en) * | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| WO2018191678A1 (en) * | 2017-04-14 | 2018-10-18 | La Jolla Pharmaceutical Company | Methods for administering angiotensin ii |
| WO2019118874A1 (en) * | 2017-12-15 | 2019-06-20 | La Jolla Pharma, Llc | Angiotensin compositions and methods related thereto |
| US20250366467A1 (en) * | 2022-06-15 | 2025-12-04 | Virginia Commonwealth University | Methods for fluid resuscitation of an organ donor |
| WO2024129057A1 (en) * | 2022-12-12 | 2024-06-20 | Proletariat Therapeutics, Inc. | Methods of treating cardiac injury |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181008B (en) | 1980-01-18 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position |
| US5216025A (en) | 1989-09-13 | 1993-06-01 | Board Of Regents, The University Of Texas System | Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients |
| US5444067A (en) | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| EP1401864A1 (en) | 2001-06-04 | 2004-03-31 | Human Genome Sciences | Methods and compositions for modulating ace-2 activity |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| JP2007510643A (ja) | 2003-11-06 | 2007-04-26 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 医薬化合物 |
| NO20034952D0 (no) | 2003-11-06 | 2003-11-06 | Amersham Health As | Farmasöytiske forbindelser |
| FR2880807B1 (fr) * | 2005-01-19 | 2007-04-13 | Aguettant Sa Lab | Composition pharmaceutique injectable |
| DE602006021600D1 (de) | 2005-09-29 | 2011-06-09 | Fibrogen Inc | Verfahren zur senkung des blutdrucks |
| AU2006332449B2 (en) | 2005-12-30 | 2008-05-15 | Howard Florey Institute Of Experimental Physiology And Medicine | A method of treatment |
| WO2007146900A2 (en) | 2006-06-15 | 2007-12-21 | Gilead Colorado, Inc. | Antihypertensive therapy method |
| WO2008130217A1 (en) * | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
| CA2678131A1 (en) | 2006-11-17 | 2008-05-22 | Antoine Andremont | Colonic delivery using zn/pectin beads with a eudragit coating. |
| WO2009009907A1 (en) * | 2007-07-18 | 2009-01-22 | The University Of British Columbia | Use of vasopressin-receptor agonists for the treatment of septic shock |
| EP2161030A1 (en) * | 2008-09-09 | 2010-03-10 | Rijksuniversiteit te Groningen | Oxytocin formulations and uses thereof |
| AU2009319856A1 (en) | 2008-11-28 | 2010-06-03 | Abbvie Inc. | Stable antibody compositions and methods for stabilizing same |
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| FR2959414B1 (fr) * | 2010-04-30 | 2016-01-08 | Luc Quintin | Combinaison de molecules aux fins de traitement d'hypotension survenant au cours du choc septique, cardiogenique, ou anaphylactique refractaire, ou hemorragique terminal, apres correction de la volemie et de l'etat de mal asthmatique refractaire |
| BR112013000744A2 (pt) | 2010-07-14 | 2020-07-14 | Cumberland Emerging Technologies, Inc | uso de um antagonista de receptor de tromboxana a2 para prevenção ou tratamento de síndrome hepatorrenal,encefalopatia hepática,e doenças associadas |
| AU2014256944B2 (en) | 2013-04-26 | 2019-06-27 | La Jolla Pharma, Llc | Compositions and methods for treating renal failure |
| US9220745B2 (en) | 2013-12-18 | 2015-12-29 | The George Washington University, a Congressionally Not-for-Profit Corporation | Angiotensin II alone or in combination for the treatment of hypotension |
| US20150286797A1 (en) | 2014-04-02 | 2015-10-08 | David R. Ratto | System and method for administering medication |
| KR20170026486A (ko) | 2014-07-08 | 2017-03-08 | 라 졸라 파마슈티칼 컴파니 | 저혈압 치료 방법 |
| WO2017120440A1 (en) | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| BR112018013847A2 (pt) | 2016-01-07 | 2018-12-18 | La Jolla Pharma Co | métodos para administrar a angiotensina ii |
| WO2018191678A1 (en) | 2017-04-14 | 2018-10-18 | La Jolla Pharmaceutical Company | Methods for administering angiotensin ii |
| WO2019118874A1 (en) | 2017-12-15 | 2019-06-20 | La Jolla Pharma, Llc | Angiotensin compositions and methods related thereto |
-
2014
- 2014-12-18 US US14/575,127 patent/US9220745B2/en active Active
- 2014-12-18 WO PCT/US2014/071186 patent/WO2015095535A1/en not_active Ceased
- 2014-12-18 CN CN201480075899.1A patent/CN106061493A/zh active Pending
- 2014-12-18 SM SM20200018T patent/SMT202000018T1/it unknown
- 2014-12-18 CN CN202011494632.XA patent/CN112546197A/zh active Pending
- 2014-12-18 KR KR1020167019427A patent/KR102399383B1/ko active Active
- 2014-12-18 KR KR1020227004084A patent/KR20220028125A/ko not_active Ceased
- 2014-12-18 PL PL14872684T patent/PL2986308T3/pl unknown
- 2014-12-18 NZ NZ721089A patent/NZ721089A/en unknown
- 2014-12-18 LT LTEP19197866.7T patent/LT3607962T/lt unknown
- 2014-12-18 EA EA201691258A patent/EA037823B1/ru unknown
- 2014-12-18 EP EP14872684.7A patent/EP2986308B1/en active Active
- 2014-12-18 CN CN202010824424.5A patent/CN111920939A/zh active Pending
- 2014-12-18 FI FIEP19197866.7T patent/FI3607962T3/fi active
- 2014-12-18 CN CN202411722811.2A patent/CN119700926A/zh active Pending
- 2014-12-18 PT PT191978667T patent/PT3607962T/pt unknown
- 2014-12-18 ES ES14872684T patent/ES2771749T3/es active Active
- 2014-12-18 HU HUE14872684A patent/HUE047062T2/hu unknown
- 2014-12-18 SM SM20250427T patent/SMT202500427T1/it unknown
- 2014-12-18 KR KR1020237012136A patent/KR20230051721A/ko not_active Ceased
- 2014-12-18 EP EP19197866.7A patent/EP3607962B1/en active Active
- 2014-12-18 PT PT148726847T patent/PT2986308T/pt unknown
- 2014-12-18 KR KR1020247034828A patent/KR20240154702A/ko active Pending
- 2014-12-18 AU AU2014364528A patent/AU2014364528C1/en active Active
- 2014-12-18 RS RS20200021A patent/RS59804B1/sr unknown
- 2014-12-18 BR BR112016013961A patent/BR112016013961A2/pt not_active Application Discontinuation
- 2014-12-18 JP JP2016539318A patent/JP6824739B2/ja active Active
- 2014-12-18 HR HRP20200009TT patent/HRP20200009T1/hr unknown
- 2014-12-18 DK DK19197866.7T patent/DK3607962T3/da active
- 2014-12-18 DK DK14872684.7T patent/DK2986308T3/da active
- 2014-12-18 CA CA2933601A patent/CA2933601A1/en active Pending
- 2014-12-18 MX MX2016008108A patent/MX380968B/es unknown
- 2014-12-18 SI SI201431450T patent/SI2986308T1/sl unknown
- 2014-12-18 LT LTEP14872684.7T patent/LT2986308T/lt unknown
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2015
- 2015-11-13 US US14/941,301 patent/US10028995B2/en active Active
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2016
- 2016-06-09 IL IL246162A patent/IL246162B/en active IP Right Grant
- 2016-06-17 MX MX2020011190A patent/MX2020011190A/es unknown
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2018
- 2018-03-01 US US15/909,617 patent/US10493124B2/en active Active
- 2018-09-19 US US16/135,608 patent/US10765722B2/en active Active
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2019
- 2019-04-12 US US16/382,850 patent/US11096983B2/en active Active
- 2019-08-23 JP JP2019153144A patent/JP7175506B2/ja active Active
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2020
- 2020-01-13 CY CY20201100026T patent/CY1122604T1/el unknown
- 2020-11-26 AU AU2020277230A patent/AU2020277230A1/en not_active Abandoned
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2021
- 2021-07-20 US US17/380,311 patent/US11559559B2/en active Active
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2022
- 2022-07-14 JP JP2022113327A patent/JP2022137224A/ja not_active Withdrawn
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2023
- 2023-01-23 US US18/157,933 patent/US20230226141A1/en not_active Abandoned
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2024
- 2024-09-18 AU AU2024219851A patent/AU2024219851A1/en active Pending
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2025
- 2025-05-09 JP JP2025078759A patent/JP2025114753A/ja active Pending
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