CY1120490T1 - Φαρμακο για την προληψη και/ή την θεραπευτικη αντιμετωπιση της πολυκυστικης νοσου των νεφρων - Google Patents

Φαρμακο για την προληψη και/ή την θεραπευτικη αντιμετωπιση της πολυκυστικης νοσου των νεφρων

Info

Publication number
CY1120490T1
CY1120490T1 CY20181100047T CY181100047T CY1120490T1 CY 1120490 T1 CY1120490 T1 CY 1120490T1 CY 20181100047 T CY20181100047 T CY 20181100047T CY 181100047 T CY181100047 T CY 181100047T CY 1120490 T1 CY1120490 T1 CY 1120490T1
Authority
CY
Cyprus
Prior art keywords
kidney disease
medicine
prevention
polycyclic
therapeutic treatment
Prior art date
Application number
CY20181100047T
Other languages
English (en)
Inventor
Hiroyuki Fujiki
Miki Aihara
Shizuo Kinoshita
Original Assignee
Otsuka Pharmaceutical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd filed Critical Otsuka Pharmaceutical Co., Ltd
Publication of CY1120490T1 publication Critical patent/CY1120490T1/el

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Ένας στόχος της παρούσας εφεύρεσης είναι η παροχή ενός φαρμάκου συνδυασμού που έχει αξιοσημείωτα εξαιρετικές προληπτικές και/ή θεραπευτικές επιδράσεις στην πολυκυστική νόσο των νεφρών. Η παρούσα εφεύρεση παρέχει ένα φάρμακο για την πρόληψη και/ή τη θεραπευτική αντιμετώπιση της πολυκυστικής νόσου των νεφρών, το οποίο περιλαμβάνει τον συνδυασμό τολβαπτάνης ή ενός προφαρμάκου αυτής με ένα παράγωγο σωματοστατίνης, και μία μέθοδο για τη θεραπευτική αντιμετώπιση της πολυκυστικής νόσου των νεφρών, χρησιμοποιώντας το εν λόγω φάρμακο.
CY20181100047T 2012-05-31 2018-01-16 Φαρμακο για την προληψη και/ή την θεραπευτικη αντιμετωπιση της πολυκυστικης νοσου των νεφρων CY1120490T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261653524P 2012-05-31 2012-05-31
PCT/JP2013/065637 WO2013180310A1 (en) 2012-05-31 2013-05-30 Drug for preventing and/or treating polycystic kidney disease

Publications (1)

Publication Number Publication Date
CY1120490T1 true CY1120490T1 (el) 2019-07-10

Family

ID=48670042

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20181100047T CY1120490T1 (el) 2012-05-31 2018-01-16 Φαρμακο για την προληψη και/ή την θεραπευτικη αντιμετωπιση της πολυκυστικης νοσου των νεφρων

Country Status (31)

Country Link
US (8) US9636382B2 (el)
EP (1) EP2854815B1 (el)
JP (4) JP6116591B2 (el)
KR (2) KR102211354B1 (el)
CN (2) CN107625953A (el)
AR (1) AR091205A1 (el)
AU (3) AU2013268343B2 (el)
BR (1) BR112014029573A2 (el)
CA (1) CA2873365A1 (el)
CO (1) CO7160102A2 (el)
CY (1) CY1120490T1 (el)
DK (1) DK2854815T3 (el)
EA (1) EA036062B1 (el)
ES (1) ES2654768T3 (el)
HK (1) HK1206992A1 (el)
HR (1) HRP20180040T1 (el)
HU (1) HUE035158T2 (el)
IL (2) IL235623A0 (el)
LT (1) LT2854815T (el)
MX (1) MX366121B (el)
MY (1) MY174625A (el)
NO (1) NO2888775T3 (el)
NZ (1) NZ630118A (el)
PH (2) PH12014502558A1 (el)
PL (1) PL2854815T3 (el)
PT (1) PT2854815T (el)
SG (2) SG11201407368VA (el)
SI (1) SI2854815T1 (el)
TW (2) TWI633887B (el)
WO (1) WO2013180310A1 (el)
ZA (1) ZA201408411B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ591810A (en) 2008-09-17 2012-12-21 Chiasma Inc Pharmaceutical compositions and related methods of delivery the composition comprises a medium chain fatty acid
TWI633887B (zh) 2012-05-31 2018-09-01 大塚製藥股份有限公司 用於預防及/或治療多囊性腎臟病之藥物
US9597283B2 (en) 2012-12-28 2017-03-21 Otsuka Pharmaceutical Co., Ltd. Injectable depot formulation comprising optically active tolvaptan and process of producing the same
TW201605488A (zh) * 2013-10-15 2016-02-16 大塚製藥股份有限公司 用以預防及/或治療多囊腎病之藥物
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
AU2017210227A1 (en) * 2016-01-21 2018-09-06 Amryt Endo, Inc. Oral octreotide for the treatment of disease
WO2019118272A1 (en) * 2017-12-11 2019-06-20 Mayo Foundation For Medical Education And Research Using probenecid to treat polycystic kidney disease
GB201905711D0 (en) * 2019-04-24 2019-06-05 Galapagos Nv Novel compounds and pharmaceutical compositions thereof for the treatment of kidney diseases
JP2022543513A (ja) 2019-08-14 2022-10-13 オートディン シス インコーポレイテッド アクセルペダル及びブレーキペダルと連動するクラッチシステム
EP3916259B1 (en) 2019-10-16 2023-10-25 Autodyn Sys Inc. Rotary shaft assembly having novel structure
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods
US20230158041A1 (en) * 2021-11-22 2023-05-25 Otsuka Pharmaceutical Co.,Ltd. Methods and compositions for treating autosomal dominant polycystic kidney disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0450097B1 (en) 1989-10-20 1996-04-24 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
JP4154765B2 (ja) 1998-09-28 2008-09-24 ダイキン工業株式会社 天井取付型の空気吹出器
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
AR044852A1 (es) 2003-06-24 2005-10-05 Novartis Ag Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina
US20100004206A1 (en) 2005-12-27 2010-01-07 Makoto Komatsu Water-soluble benzoazepine compound and its pharmaceutical composition
GB0602639D0 (en) 2006-02-09 2006-03-22 Novartis Ag Organic compounds
CA2647986C (en) 2006-03-31 2014-07-08 Erasmus University Medical Center Rotterdam Compositions for tumor growth control
BRPI0712051A2 (pt) * 2006-06-08 2012-01-10 Novartis Ag combinação de análogos de somatostatina com antagonista de receptor do hormÈnio de crescimento ou dopamina
TWI459947B (zh) 2007-06-26 2014-11-11 Otsuka Pharma Co Ltd 苯并氮呯化合物及藥學製劑
TWI633887B (zh) 2012-05-31 2018-09-01 大塚製藥股份有限公司 用於預防及/或治療多囊性腎臟病之藥物

Also Published As

Publication number Publication date
NZ630118A (en) 2016-07-29
KR102127180B1 (ko) 2020-06-29
JP2017110029A (ja) 2017-06-22
HK1206992A1 (en) 2016-01-22
US20190117666A1 (en) 2019-04-25
US20160058841A1 (en) 2016-03-03
US20150141338A1 (en) 2015-05-21
EP2854815A1 (en) 2015-04-08
HUE035158T2 (hu) 2018-05-02
HRP20180040T1 (hr) 2018-02-09
US11957691B2 (en) 2024-04-16
EA201492279A1 (ru) 2015-05-29
KR20150016597A (ko) 2015-02-12
PL2854815T3 (pl) 2018-03-30
MX366121B (es) 2019-06-27
JP2015517974A (ja) 2015-06-25
US20220241293A1 (en) 2022-08-04
CN104334176B (zh) 2018-01-02
US20170196877A1 (en) 2017-07-13
PT2854815T (pt) 2017-12-20
AU2013268343A1 (en) 2014-11-27
TW201827056A (zh) 2018-08-01
KR20200034811A (ko) 2020-03-31
MX2014014476A (es) 2015-02-12
AR091205A1 (es) 2015-01-21
AU2019202158A1 (en) 2019-04-18
AU2013268343B2 (en) 2017-06-01
MY174625A (en) 2020-05-03
US20170239265A1 (en) 2017-08-24
EP2854815B1 (en) 2017-11-22
JP6116591B2 (ja) 2017-04-19
PH12014502558B1 (en) 2015-01-21
CN107625953A (zh) 2018-01-26
CA2873365A1 (en) 2013-12-05
NO2888775T3 (el) 2018-08-04
US20190374549A1 (en) 2019-12-12
DK2854815T3 (en) 2018-01-22
AU2017202757A1 (en) 2017-05-18
IL235623A0 (en) 2015-01-29
JP2019001801A (ja) 2019-01-10
TW201400118A (zh) 2014-01-01
JP2020117535A (ja) 2020-08-06
CN104334176A (zh) 2015-02-04
AU2019202158B2 (en) 2020-06-25
BR112014029573A2 (pt) 2017-06-27
WO2013180310A1 (en) 2013-12-05
US11013746B2 (en) 2021-05-25
US9636382B2 (en) 2017-05-02
TWI704919B (zh) 2020-09-21
ES2654768T3 (es) 2018-02-15
CO7160102A2 (es) 2015-01-15
KR102211354B1 (ko) 2021-02-03
JP6938705B2 (ja) 2021-09-22
IL253441A0 (en) 2017-09-28
PH12014502558A1 (en) 2015-01-21
ZA201408411B (en) 2016-09-28
EA036062B1 (ru) 2020-09-22
SI2854815T1 (en) 2018-02-28
JP6724085B2 (ja) 2020-07-15
LT2854815T (lt) 2018-02-12
US20240216389A1 (en) 2024-07-04
SG10201609250QA (en) 2016-12-29
PH12018501227A1 (en) 2020-09-14
US11147821B2 (en) 2021-10-19
SG11201407368VA (en) 2015-01-29
TWI633887B (zh) 2018-09-01
US9669075B2 (en) 2017-06-06

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