MX380968B - Angiotensina ii sola o en combinacion para usarse en el tratamiento de hipotension. - Google Patents
Angiotensina ii sola o en combinacion para usarse en el tratamiento de hipotension.Info
- Publication number
- MX380968B MX380968B MX2016008108A MX2016008108A MX380968B MX 380968 B MX380968 B MX 380968B MX 2016008108 A MX2016008108 A MX 2016008108A MX 2016008108 A MX2016008108 A MX 2016008108A MX 380968 B MX380968 B MX 380968B
- Authority
- MX
- Mexico
- Prior art keywords
- angiotensin
- mcg
- dose
- equivalent
- treatment
- Prior art date
Links
- 102000005862 Angiotensin II Human genes 0.000 title abstract 2
- 101800000733 Angiotensin-2 Proteins 0.000 title abstract 2
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 title abstract 2
- 229950006323 angiotensin ii Drugs 0.000 title abstract 2
- 208000001953 Hypotension Diseases 0.000 title 1
- 230000036543 hypotension Effects 0.000 title 1
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 3
- 229960002748 norepinephrine Drugs 0.000 abstract 3
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 3
- 150000003943 catecholamines Chemical class 0.000 abstract 2
- 230000004872 arterial blood pressure Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361917576P | 2013-12-18 | 2013-12-18 | |
| US201461955706P | 2014-03-19 | 2014-03-19 | |
| PCT/US2014/071186 WO2015095535A1 (en) | 2013-12-18 | 2014-12-18 | Angiotensin ii alone or in combination for the treatment of hypotension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016008108A MX2016008108A (es) | 2017-03-09 |
| MX380968B true MX380968B (es) | 2025-03-12 |
Family
ID=53367119
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016008108A MX380968B (es) | 2013-12-18 | 2014-12-18 | Angiotensina ii sola o en combinacion para usarse en el tratamiento de hipotension. |
| MX2020011190A MX2020011190A (es) | 2013-12-18 | 2016-06-17 | Angiotensina ii sola o en combinacion para usarse en el tratamiento de hipotension. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020011190A MX2020011190A (es) | 2013-12-18 | 2016-06-17 | Angiotensina ii sola o en combinacion para usarse en el tratamiento de hipotension. |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US9220745B2 (enExample) |
| EP (2) | EP2986308B1 (enExample) |
| JP (4) | JP6824739B2 (enExample) |
| KR (4) | KR102399383B1 (enExample) |
| CN (4) | CN106061493A (enExample) |
| AU (3) | AU2014364528C1 (enExample) |
| BR (1) | BR112016013961A2 (enExample) |
| CA (1) | CA2933601A1 (enExample) |
| CY (1) | CY1122604T1 (enExample) |
| DK (2) | DK3607962T3 (enExample) |
| EA (1) | EA037823B1 (enExample) |
| ES (1) | ES2771749T3 (enExample) |
| FI (1) | FI3607962T3 (enExample) |
| HR (1) | HRP20200009T1 (enExample) |
| HU (1) | HUE047062T2 (enExample) |
| IL (1) | IL246162B (enExample) |
| LT (1) | LT2986308T (enExample) |
| MX (2) | MX380968B (enExample) |
| NZ (1) | NZ721089A (enExample) |
| PL (1) | PL2986308T3 (enExample) |
| PT (1) | PT2986308T (enExample) |
| RS (1) | RS59804B1 (enExample) |
| SI (1) | SI2986308T1 (enExample) |
| SM (1) | SMT202000018T1 (enExample) |
| WO (1) | WO2015095535A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| AU2014364528C1 (en) | 2013-12-18 | 2021-01-07 | The George Washington University, A Congressional Chartered Not-For-Profit Corporation | Angiotensin ll alone or in combination for the treatment of hypotension |
| TWI754225B (zh) * | 2014-07-08 | 2022-02-01 | 美商拉荷亞製藥公司 | 治療低血壓之方法 |
| WO2016153558A1 (en) | 2015-03-20 | 2016-09-29 | Atkinson Arthur J | Use of angiotensin ii (aii) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps |
| EP3400000B1 (en) * | 2016-01-07 | 2023-12-06 | La Jolla Pharma, LLC | Methods for administering angiotensin ii |
| CA3010788A1 (en) * | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| US11583568B2 (en) | 2017-04-14 | 2023-02-21 | La Jolla Pharma, Llc | Methods for administering angiotensin II |
| TW201927331A (zh) * | 2017-12-15 | 2019-07-16 | 美商拉荷亞製藥公司 | 血管收縮素組合物及與其相關之方法 |
| WO2023244552A1 (en) * | 2022-06-15 | 2023-12-21 | Virginia Commonwealth University | Methods for fluid resuscitation of an organ donor |
| EP4633658A1 (en) * | 2022-12-12 | 2025-10-22 | Proletariat Therapeutics, Inc. | Methods of treating cardiac injury |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181008B (en) | 1980-01-18 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position |
| US5216025A (en) * | 1989-09-13 | 1993-06-01 | Board Of Regents, The University Of Texas System | Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients |
| US5444067A (en) | 1993-08-30 | 1995-08-22 | Merck & Co., Inc. | Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety |
| CA2448051A1 (en) | 2001-06-04 | 2002-12-12 | Human Genome Sciences, Inc. | Methods and compositions for modulating ace-2 activity |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| NO20034952D0 (no) | 2003-11-06 | 2003-11-06 | Amersham Health As | Farmasöytiske forbindelser |
| US7785566B2 (en) | 2003-11-06 | 2010-08-31 | Ge Healthcare, Inc. | Pharmaceutical compounds |
| FR2880807B1 (fr) * | 2005-01-19 | 2007-04-13 | Aguettant Sa Lab | Composition pharmaceutique injectable |
| ATE507243T1 (de) | 2005-09-29 | 2011-05-15 | Fibrogen Inc | Verfahren zur senkung des blutdrucks |
| EP1971358A4 (en) * | 2005-12-30 | 2010-05-26 | Florey Howard Inst | Methods of Treatment |
| WO2007146900A2 (en) | 2006-06-15 | 2007-12-21 | Gilead Colorado, Inc. | Antihypertensive therapy method |
| WO2008130217A1 (en) * | 2006-08-08 | 2008-10-30 | Applied Nanosystems B.V. | Cyclic angiotensin analogs |
| CA2678131A1 (en) | 2006-11-17 | 2008-05-22 | Antoine Andremont | Colonic delivery using zn/pectin beads with a eudragit coating. |
| WO2009009907A1 (en) * | 2007-07-18 | 2009-01-22 | The University Of British Columbia | Use of vasopressin-receptor agonists for the treatment of septic shock |
| EP2161030A1 (en) * | 2008-09-09 | 2010-03-10 | Rijksuniversiteit te Groningen | Oxytocin formulations and uses thereof |
| WO2010062896A1 (en) | 2008-11-28 | 2010-06-03 | Abbott Laboratories | Stable antibody compositions and methods for stabilizing same |
| US9572856B2 (en) | 2009-12-16 | 2017-02-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Method of treating low blood pressure |
| FR2959414B1 (fr) * | 2010-04-30 | 2016-01-08 | Luc Quintin | Combinaison de molecules aux fins de traitement d'hypotension survenant au cours du choc septique, cardiogenique, ou anaphylactique refractaire, ou hemorragique terminal, apres correction de la volemie et de l'etat de mal asthmatique refractaire |
| KR20130026504A (ko) | 2010-07-14 | 2013-03-13 | 큠버랜드 에멀징 테크놀로지스 아이앤씨 | 트롬복산-a2 수용체 길항제를 이용한 간신증후군 및 간성뇌증의 치료방법 |
| EP2988770A4 (en) | 2013-04-26 | 2016-12-14 | La Jolla Pharma Co | COMPOSITIONS AND METHOD FOR TREATING KIDNEY FAILURES |
| AU2014364528C1 (en) | 2013-12-18 | 2021-01-07 | The George Washington University, A Congressional Chartered Not-For-Profit Corporation | Angiotensin ll alone or in combination for the treatment of hypotension |
| US20150286797A1 (en) | 2014-04-02 | 2015-10-08 | David R. Ratto | System and method for administering medication |
| TWI754225B (zh) | 2014-07-08 | 2022-02-01 | 美商拉荷亞製藥公司 | 治療低血壓之方法 |
| CA3010788A1 (en) | 2016-01-07 | 2017-07-13 | La Jolla Pharmaceutical Company | Methods of administering vasopressors |
| EP3400000B1 (en) | 2016-01-07 | 2023-12-06 | La Jolla Pharma, LLC | Methods for administering angiotensin ii |
| US11583568B2 (en) | 2017-04-14 | 2023-02-21 | La Jolla Pharma, Llc | Methods for administering angiotensin II |
| TW201927331A (zh) | 2017-12-15 | 2019-07-16 | 美商拉荷亞製藥公司 | 血管收縮素組合物及與其相關之方法 |
-
2014
- 2014-12-18 AU AU2014364528A patent/AU2014364528C1/en active Active
- 2014-12-18 DK DK19197866.7T patent/DK3607962T3/da active
- 2014-12-18 CA CA2933601A patent/CA2933601A1/en active Pending
- 2014-12-18 DK DK14872684.7T patent/DK2986308T3/da active
- 2014-12-18 US US14/575,127 patent/US9220745B2/en active Active
- 2014-12-18 KR KR1020167019427A patent/KR102399383B1/ko active Active
- 2014-12-18 KR KR1020227004084A patent/KR20220028125A/ko not_active Ceased
- 2014-12-18 CN CN201480075899.1A patent/CN106061493A/zh active Pending
- 2014-12-18 LT LTEP14872684.7T patent/LT2986308T/lt unknown
- 2014-12-18 KR KR1020237012136A patent/KR20230051721A/ko not_active Ceased
- 2014-12-18 EP EP14872684.7A patent/EP2986308B1/en active Active
- 2014-12-18 KR KR1020247034828A patent/KR20240154702A/ko active Pending
- 2014-12-18 ES ES14872684T patent/ES2771749T3/es active Active
- 2014-12-18 RS RS20200021A patent/RS59804B1/sr unknown
- 2014-12-18 SM SM20200018T patent/SMT202000018T1/it unknown
- 2014-12-18 PL PL14872684T patent/PL2986308T3/pl unknown
- 2014-12-18 HU HUE14872684A patent/HUE047062T2/hu unknown
- 2014-12-18 EA EA201691258A patent/EA037823B1/ru unknown
- 2014-12-18 FI FIEP19197866.7T patent/FI3607962T3/fi active
- 2014-12-18 WO PCT/US2014/071186 patent/WO2015095535A1/en not_active Ceased
- 2014-12-18 CN CN202411722811.2A patent/CN119700926A/zh active Pending
- 2014-12-18 PT PT148726847T patent/PT2986308T/pt unknown
- 2014-12-18 HR HRP20200009TT patent/HRP20200009T1/hr unknown
- 2014-12-18 EP EP19197866.7A patent/EP3607962B1/en active Active
- 2014-12-18 CN CN202010824424.5A patent/CN111920939A/zh active Pending
- 2014-12-18 SI SI201431450T patent/SI2986308T1/sl unknown
- 2014-12-18 NZ NZ721089A patent/NZ721089A/en unknown
- 2014-12-18 MX MX2016008108A patent/MX380968B/es unknown
- 2014-12-18 CN CN202011494632.XA patent/CN112546197A/zh active Pending
- 2014-12-18 BR BR112016013961A patent/BR112016013961A2/pt not_active Application Discontinuation
- 2014-12-18 JP JP2016539318A patent/JP6824739B2/ja active Active
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2015
- 2015-11-13 US US14/941,301 patent/US10028995B2/en active Active
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2016
- 2016-06-09 IL IL246162A patent/IL246162B/en active IP Right Grant
- 2016-06-17 MX MX2020011190A patent/MX2020011190A/es unknown
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2018
- 2018-03-01 US US15/909,617 patent/US10493124B2/en active Active
- 2018-09-19 US US16/135,608 patent/US10765722B2/en active Active
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2019
- 2019-04-12 US US16/382,850 patent/US11096983B2/en active Active
- 2019-08-23 JP JP2019153144A patent/JP7175506B2/ja active Active
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2020
- 2020-01-13 CY CY20201100026T patent/CY1122604T1/el unknown
- 2020-11-26 AU AU2020277230A patent/AU2020277230A1/en not_active Abandoned
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2021
- 2021-07-20 US US17/380,311 patent/US11559559B2/en active Active
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2022
- 2022-07-14 JP JP2022113327A patent/JP2022137224A/ja not_active Withdrawn
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2023
- 2023-01-23 US US18/157,933 patent/US20230226141A1/en not_active Abandoned
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2024
- 2024-09-18 AU AU2024219851A patent/AU2024219851A1/en active Pending
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2025
- 2025-05-09 JP JP2025078759A patent/JP2025114753A/ja active Pending
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