CO2019009000A2 - Combinaciones farmacéuticas para tratar cáncer - Google Patents
Combinaciones farmacéuticas para tratar cáncerInfo
- Publication number
- CO2019009000A2 CO2019009000A2 CONC2019/0009000A CO2019009000A CO2019009000A2 CO 2019009000 A2 CO2019009000 A2 CO 2019009000A2 CO 2019009000 A CO2019009000 A CO 2019009000A CO 2019009000 A2 CO2019009000 A2 CO 2019009000A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical combinations
- tyr
- treat cancer
- dpro
- cys
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a combinaciones farmacéuticas que comprenden un compuesto de fórmula I o una sal farmacéuticamente aceptable del mismo y ciclo (-Tyr-His-Ala-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-DPro-Pro-) que tiene un enlace de disulfuro entre Cys4 y Cys11 o una sal farmacéuticamente aceptable del mismo y su uso en un método para la prevención, retraso o progreso de tratamiento de cáncer en un sujeto.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17020059 | 2017-02-20 | ||
PCT/EP2018/025042 WO2018149552A1 (en) | 2017-02-20 | 2018-02-20 | Pharmaceutical combinations for treating cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2019009000A2 true CO2019009000A2 (es) | 2020-01-17 |
Family
ID=58108397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2019/0009000A CO2019009000A2 (es) | 2017-02-20 | 2019-08-20 | Combinaciones farmacéuticas para tratar cáncer |
Country Status (19)
Country | Link |
---|---|
US (2) | US20210187059A1 (es) |
EP (1) | EP3582804A1 (es) |
JP (1) | JP2020508315A (es) |
KR (1) | KR20190138633A (es) |
CN (1) | CN110603051A (es) |
AU (1) | AU2018221371A1 (es) |
BR (1) | BR112019017047A2 (es) |
CA (1) | CA3053857A1 (es) |
CL (1) | CL2019002325A1 (es) |
CO (1) | CO2019009000A2 (es) |
EA (1) | EA201991688A1 (es) |
IL (1) | IL268416B2 (es) |
MA (1) | MA47502A (es) |
MX (1) | MX2019009779A (es) |
PE (1) | PE20200149A1 (es) |
PH (1) | PH12019550138A1 (es) |
SG (1) | SG11201907217RA (es) |
UA (1) | UA126029C2 (es) |
WO (1) | WO2018149552A1 (es) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11407762B2 (en) | 2017-11-15 | 2022-08-09 | President And Fellows Of Harvard College | Macrocyclic compounds and uses thereof |
US11498892B2 (en) | 2017-07-06 | 2022-11-15 | President And Fellows Of Harvard College | Fe/Cu-mediated ketone synthesis |
US11548898B2 (en) | 2017-07-06 | 2023-01-10 | President And Fellows Of Harvard College | Synthesis of halichondrins |
US11725015B2 (en) | 2017-04-05 | 2023-08-15 | President And Fellows Of Harvard College | Macrocyclic compound and uses thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022167157A1 (en) * | 2021-02-05 | 2022-08-11 | Spexis Ag | Eribulin-balixafortide combinations for treating cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20150090921A (ko) * | 2012-12-04 | 2015-08-06 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 유방암 치료에서 에리불린의 용도 |
WO2015183961A1 (en) * | 2014-05-28 | 2015-12-03 | Eisai R&D Management Co., Ltd | Use of eribulin in the treatment of cancer |
-
2018
- 2018-02-20 KR KR1020197027328A patent/KR20190138633A/ko not_active Application Discontinuation
- 2018-02-20 EP EP18709923.9A patent/EP3582804A1/en not_active Withdrawn
- 2018-02-20 JP JP2019545318A patent/JP2020508315A/ja active Pending
- 2018-02-20 SG SG11201907217RA patent/SG11201907217RA/en unknown
- 2018-02-20 CA CA3053857A patent/CA3053857A1/en active Pending
- 2018-02-20 PE PE2019001731A patent/PE20200149A1/es unknown
- 2018-02-20 WO PCT/EP2018/025042 patent/WO2018149552A1/en unknown
- 2018-02-20 UA UAA201909893A patent/UA126029C2/uk unknown
- 2018-02-20 MA MA047502A patent/MA47502A/fr unknown
- 2018-02-20 EA EA201991688A patent/EA201991688A1/ru unknown
- 2018-02-20 BR BR112019017047A patent/BR112019017047A2/pt not_active IP Right Cessation
- 2018-02-20 MX MX2019009779A patent/MX2019009779A/es unknown
- 2018-02-20 AU AU2018221371A patent/AU2018221371A1/en active Pending
- 2018-02-20 US US16/486,945 patent/US20210187059A1/en not_active Abandoned
- 2018-02-20 CN CN201880012987.5A patent/CN110603051A/zh active Pending
-
2019
- 2019-08-01 IL IL268416A patent/IL268416B2/en unknown
- 2019-08-05 PH PH12019550138A patent/PH12019550138A1/en unknown
- 2019-08-16 CL CL2019002325A patent/CL2019002325A1/es unknown
- 2019-08-20 CO CONC2019/0009000A patent/CO2019009000A2/es unknown
-
2023
- 2023-04-05 US US18/296,104 patent/US20230381270A1/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11725015B2 (en) | 2017-04-05 | 2023-08-15 | President And Fellows Of Harvard College | Macrocyclic compound and uses thereof |
US11498892B2 (en) | 2017-07-06 | 2022-11-15 | President And Fellows Of Harvard College | Fe/Cu-mediated ketone synthesis |
US11548898B2 (en) | 2017-07-06 | 2023-01-10 | President And Fellows Of Harvard College | Synthesis of halichondrins |
US11407762B2 (en) | 2017-11-15 | 2022-08-09 | President And Fellows Of Harvard College | Macrocyclic compounds and uses thereof |
US11814398B2 (en) | 2017-11-15 | 2023-11-14 | President And Fellows Of Harvard College | Macrocyclic compounds and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
EP3582804A1 (en) | 2019-12-25 |
PE20200149A1 (es) | 2020-01-17 |
AU2018221371A1 (en) | 2019-08-22 |
IL268416B2 (en) | 2023-05-01 |
KR20190138633A (ko) | 2019-12-13 |
UA126029C2 (uk) | 2022-08-03 |
MX2019009779A (es) | 2019-12-19 |
IL268416A (en) | 2019-09-26 |
WO2018149552A1 (en) | 2018-08-23 |
MA47502A (fr) | 2019-12-25 |
EA201991688A1 (ru) | 2020-02-12 |
BR112019017047A2 (pt) | 2020-04-28 |
JP2020508315A (ja) | 2020-03-19 |
US20230381270A1 (en) | 2023-11-30 |
US20210187059A1 (en) | 2021-06-24 |
CN110603051A (zh) | 2019-12-20 |
PH12019550138A1 (en) | 2020-03-16 |
CA3053857A1 (en) | 2018-08-23 |
IL268416B1 (en) | 2023-01-01 |
CL2019002325A1 (es) | 2020-05-15 |
SG11201907217RA (en) | 2019-09-27 |
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