CY1121910T1 - Φαρμακευτικο παρασκευασμα που περιεχει παραγωγο διυδροκιναζολινης με αντιϊικη δραση - Google Patents

Φαρμακευτικο παρασκευασμα που περιεχει παραγωγο διυδροκιναζολινης με αντιϊικη δραση

Info

Publication number
CY1121910T1
CY1121910T1 CY20191100885T CY191100885T CY1121910T1 CY 1121910 T1 CY1121910 T1 CY 1121910T1 CY 20191100885 T CY20191100885 T CY 20191100885T CY 191100885 T CY191100885 T CY 191100885T CY 1121910 T1 CY1121910 T1 CY 1121910T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical preparation
preparation containing
antibiotic activity
dihydroquinazoline derivative
dihydroquinazoline
Prior art date
Application number
CY20191100885T
Other languages
Greek (el)
English (en)
Inventor
Kerstin Paulus
Wilfried Schwab
Dominique Grunder
Peter Van Hoogevest
Original Assignee
Aicuris Anti-Infective Cures Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47757622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1121910(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aicuris Anti-Infective Cures Gmbh filed Critical Aicuris Anti-Infective Cures Gmbh
Publication of CY1121910T1 publication Critical patent/CY1121910T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CY20191100885T 2012-02-29 2019-08-20 Φαρμακευτικο παρασκευασμα που περιεχει παραγωγο διυδροκιναζολινης με αντιϊικη δραση CY1121910T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012101680A DE102012101680A1 (de) 2012-02-29 2012-02-29 Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat
PCT/EP2013/054114 WO2013127970A1 (de) 2012-02-29 2013-02-28 Pharmazeutische zubereitung enthaltend ein antiviral wirksames dihydrochinazolinderivat

Publications (1)

Publication Number Publication Date
CY1121910T1 true CY1121910T1 (el) 2020-10-14

Family

ID=47757622

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100885T CY1121910T1 (el) 2012-02-29 2019-08-20 Φαρμακευτικο παρασκευασμα που περιεχει παραγωγο διυδροκιναζολινης με αντιϊικη δραση

Country Status (37)

Country Link
US (1) US10603384B2 (enExample)
EP (3) EP2819648B1 (enExample)
JP (1) JP6387486B2 (enExample)
KR (1) KR102149561B1 (enExample)
CN (2) CN110433166A (enExample)
AU (1) AU2013224947B2 (enExample)
BR (1) BR112014020946B1 (enExample)
CA (1) CA2865203C (enExample)
CL (1) CL2014002306A1 (enExample)
CO (1) CO7061076A2 (enExample)
CY (1) CY1121910T1 (enExample)
DE (1) DE102012101680A1 (enExample)
DK (2) DK2819648T3 (enExample)
EA (1) EA026584B1 (enExample)
ES (2) ES2972133T3 (enExample)
FI (1) FI3556350T3 (enExample)
HR (2) HRP20240197T1 (enExample)
HU (2) HUE045949T2 (enExample)
IL (1) IL234363B (enExample)
IN (1) IN2014MN01892A (enExample)
LT (2) LT3556350T (enExample)
MA (1) MA35941B1 (enExample)
ME (1) ME03448B (enExample)
MX (1) MX369666B (enExample)
MY (1) MY172310A (enExample)
NZ (1) NZ628444A (enExample)
PH (1) PH12014501937B1 (enExample)
PL (2) PL2819648T3 (enExample)
PT (2) PT2819648T (enExample)
RS (2) RS59157B1 (enExample)
SG (1) SG11201405294XA (enExample)
SI (2) SI3556350T1 (enExample)
SM (2) SMT201900458T1 (enExample)
TN (1) TN2014000345A1 (enExample)
UA (1) UA111415C2 (enExample)
WO (1) WO2013127970A1 (enExample)
ZA (1) ZA201405949B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
MD4673C1 (ro) * 2013-06-19 2020-11-30 Aicuris Anti-Infective Cures Gmbh Letermovir amorf şi forme preparative farmaceutice solide ale acestuia pentru administrare orală
AU2017274722A1 (en) 2016-06-03 2019-01-17 Atreya Innovations Private Limited A device for the detection and reliable capturing of the pulse characteristics
PH12019502037B1 (en) * 2017-03-06 2024-06-05 Everest Medicines Singapore Pte Ltd Solid forms and combination compositions comprising a beta-lactamase inhibitor and uses thereof
DK3886798T3 (da) 2018-11-29 2026-04-20 Basilea Pharmaceutica Int Ag Allschwil Kombinationssammensætninger, som omfatter en beta-lactamase-hæmmer, og anvendelser deraf
UY39097A (es) 2020-02-27 2021-09-30 Aic246 Gmbh & Co Kg Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3- metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acético
AR121438A1 (es) 2020-02-27 2022-06-08 Aic246 Gmbh & Co Kg Composiciones farmacéuticas que comprenden acetato de 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il] e iones de sodio
UY39099A (es) * 2020-02-27 2021-08-31 Aic246 Gmbh & Co Kg 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il] acetato de sodio y composiciones farmacéuticas del mismo
CN114539085B (zh) * 2020-11-26 2023-10-20 山东诚创蓝海医药科技有限公司 一种脲基衍生物的制备
CN115403528B (zh) * 2021-05-27 2025-01-07 南京正大天晴制药有限公司 无定形3,4-二氢喹唑啉衍生物的制备方法
CN113880776B (zh) * 2021-11-16 2023-06-16 山东诚创蓝海医药科技有限公司 一种莱特莫韦中间体的制备方法
UY40078A (es) 2021-12-21 2023-06-30 Aic246 Ag & Co Kg Composiciones farmacéuticas que comprenden acetato de 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin
EP4467126A4 (en) * 2022-02-23 2025-04-30 LG Chem, Ltd. Injectable formulation containing isoxazoline derivative and method for producing the same
CN115322157B (zh) * 2022-06-02 2023-12-05 浙江车头制药股份有限公司 来特莫韦中间体化合物及其制备方法和应用
CN119731157A (zh) * 2022-08-15 2025-03-28 上海迪赛诺化学制药有限公司 一种来特莫韦无定形的制备方法
CN115677539B (zh) * 2022-11-01 2023-10-24 南京工业大学 一种温和条件下钴催化脲基导向芳烃的高选择性单烯基化的方法
CN119015222B (zh) * 2024-08-28 2025-12-09 石家庄四药有限公司 一种来特莫韦注射液及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1242699A (en) * 1985-02-01 1988-10-04 Bristol-Myers Company Cefbuperazone and derivatives thereof
CA1284994C (en) * 1985-08-05 1991-06-18 Murray Arthur Kaplan Cephalosporin salts and injectable compositions
JP3552240B2 (ja) * 1993-02-23 2004-08-11 第一製薬株式会社 高濃度tcf製剤
JPH11209277A (ja) * 1998-01-19 1999-08-03 Yoshitomi Pharmaceut Ind Ltd 医薬組成物
IT1304190B1 (it) * 1998-12-18 2001-03-08 Euphar Group Srl Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche
DE60010448T2 (de) * 1999-03-17 2005-04-07 Astrazeneca Ab Amid-derivate
WO2001091751A1 (en) * 2000-05-30 2001-12-06 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
DE10319612A1 (de) * 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
SI1689724T1 (sl) * 2003-11-25 2012-04-30 Novartis Ag Spojine kinazolinona kot sredstva proti raku
WO2006086464A2 (en) * 2005-02-10 2006-08-17 Bristol-Myers Squibb Company Dihydroquinazolinones as 5ht modulators
DE102005027517A1 (de) 2005-06-15 2006-12-21 Bayer Healthcare Ag Verfahren zur Herstellung von Dihydrochinazolinen
US8743287B2 (en) * 2009-07-24 2014-06-03 Broadcom Corporation Method and system for mitigating motion trail artifacts and improving low contrast contours in temporal filtering based noise reduction

Also Published As

Publication number Publication date
SMT202400068T1 (it) 2024-03-13
EA201400963A1 (ru) 2015-02-27
EP2819648A1 (de) 2015-01-07
EP2819648B1 (de) 2019-05-29
KR102149561B1 (ko) 2020-08-31
ZA201405949B (en) 2021-07-28
HRP20191369T1 (hr) 2019-11-01
HRP20240197T1 (hr) 2024-04-26
ES2741698T3 (es) 2020-02-12
CL2014002306A1 (es) 2014-11-28
RS59157B1 (sr) 2019-10-31
LT2819648T (lt) 2019-09-10
US20150133461A1 (en) 2015-05-14
EP3556350B1 (de) 2024-01-10
HK1205462A1 (en) 2015-12-18
JP6387486B2 (ja) 2018-09-12
MA35941B1 (fr) 2014-12-01
MX2014010364A (es) 2014-12-05
KR20140130683A (ko) 2014-11-11
DK2819648T3 (da) 2019-08-26
HUE045949T2 (hu) 2020-01-28
LT3556350T (lt) 2024-02-26
PH12014501937B1 (en) 2022-07-15
DK3556350T3 (da) 2024-02-12
EP3556350A1 (de) 2019-10-23
IL234363B (en) 2020-04-30
ES2972133T3 (es) 2024-06-11
BR112014020946A2 (enExample) 2017-06-20
PL3556350T3 (pl) 2024-05-06
NZ628444A (en) 2016-07-29
PL2819648T3 (pl) 2019-10-31
MX369666B (es) 2019-11-14
CN110433166A (zh) 2019-11-12
EA026584B1 (ru) 2017-04-28
TN2014000345A1 (en) 2015-12-21
DE102012101680A1 (de) 2013-08-29
PH12014501937A1 (en) 2014-11-24
SI3556350T1 (sl) 2024-03-29
MY172310A (en) 2019-11-21
CO7061076A2 (es) 2014-09-19
HUE065553T2 (hu) 2024-06-28
IN2014MN01892A (enExample) 2015-07-10
AU2013224947B2 (en) 2017-06-29
ME03448B (me) 2020-01-20
PT2819648T (pt) 2019-09-05
SG11201405294XA (en) 2014-11-27
CN104144678A (zh) 2014-11-12
BR112014020946B1 (pt) 2022-04-05
FI3556350T3 (fi) 2024-02-14
WO2013127970A1 (de) 2013-09-06
CA2865203A1 (en) 2013-09-06
SMT201900458T1 (it) 2019-11-13
CA2865203C (en) 2019-11-05
SI2819648T1 (sl) 2019-10-30
RS65137B1 (sr) 2024-02-29
US10603384B2 (en) 2020-03-31
AU2013224947A1 (en) 2014-09-18
PT3556350T (pt) 2024-02-15
JP2015508801A (ja) 2015-03-23
UA111415C2 (uk) 2016-04-25
EP4328218A3 (de) 2024-04-10
EP4328218A2 (de) 2024-02-28

Similar Documents

Publication Publication Date Title
UA111415C2 (uk) Фармацевтичний препарат, що містить похідну дигідрохіназоліну з противірусною активністю
CY1124928T1 (el) Αναστολεις πυραζολυλο κινοξαλινο κινασης
CY1121150T1 (el) Νευροδραστικα 19-αλκοξυ-17-υποκατεστημενα στεροειδη, χρησιμα σε μεθοδους θεραπειας
CY1120832T1 (el) Τροποποιητες πυρηνικης μεταφορας και χρησεις αυτων
CY1124000T1 (el) Υποκατεστημενες 5-φθορο-1η-πυραζολοπυριδινες σε κρυσταλλικη μορφη
CY1122730T1 (el) 1,2,4-τριαζολες ως διαμορφωτες πυρηνικης μεταφορας και χρησεις αυτων
CY1120031T1 (el) Αποπτωτικοι υποκινητες ν-ακυλοσουλφοναμιδης
CY1120429T1 (el) Παραγωγα κιναζολινης για τη θεραπευτικη αντιμετωπιση ιογενων λοιμωξεων και αλλων νοσων
CY1119058T1 (el) Ενωσεις ιμιδαζοπυρρολιδινονης
CY1117796T1 (el) Μετα νατριου και ασβεστιου αλατα παραγωγου διυδροκινζολινης και η χρηση αυτων ως αντι-ιικα μεσα
EA201600204A1 (ru) Производные хиназолина, фармацевтическая композиция на их основе и их применение для профилактики или лечения опухоли
CY1118379T1 (el) Αναστολεις ιου ηπατιτιδας c
CY1119490T1 (el) Παραγωγα πυραζολοπυρρολιδινης και η χρηση τους στην θεραπεια νοσηματων
MX373042B (es) Moleculas para administracion a celulas cancerosas mutantes ros1.
UA109010C2 (en) Morpholino pyrividines and their use in therapy
MD20140063A2 (ro) Derivaţi de acid benzotiazol-6-il acetic şi utilizarea acestora pentru tratarea unei infecţii HIV
BR112015000704A2 (pt) imidazotriazinacarbonitrilas úteis como inibidores de quinase
NZ626618A (en) Hydroxamic acid derivatives and uses thereof
CY1118284T1 (el) Βεσυλικα και τοσυλικα αλατα ενος παραγωγου διυδροκιναζολινης και χρηση αυτων ως αντιικων παραγοντων
JO3122B1 (ar) مشتقات إسترا-5،3،1(10)، 16- تترايين-3- كربوكساميد، عمليات لتحضيرها، مستحضرات دوائية تشتمل عليها واستخدامها لتحضير أدوية
EA201591957A1 (ru) Производные глутаримидов, их применение, фармацевтическая композиция на их основе, способы их получения
BR102012028120B8 (pt) Uso de um ou mais derivados de ingenol, composição farmacêutica e medicamento
NZ712540A (en) Phenyl derivative having s1p2 antagonistic activity
TH103144B (th) องค์ประกอบทางเภสัชกรรมที่มีอนุพันธ์ไดไฮโดรควิแนโซลีนซึ่งออกฤทธิ์ต่อต้านไวรัส
TH152461A (th) 3-ไพริมิดิน-4-อิล-ออกซะโซลิดิน-2-โอนในรูปตัวยับยั้งของ idh ที่กลายพันธุ์