CY1118459T1 - Απο του στοματος φαρμακευτικη συνθεση δεσμοπρεσινης - Google Patents
Απο του στοματος φαρμακευτικη συνθεση δεσμοπρεσινηςInfo
- Publication number
- CY1118459T1 CY1118459T1 CY20171100005T CY171100005T CY1118459T1 CY 1118459 T1 CY1118459 T1 CY 1118459T1 CY 20171100005 T CY20171100005 T CY 20171100005T CY 171100005 T CY171100005 T CY 171100005T CY 1118459 T1 CY1118459 T1 CY 1118459T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmaceutical composition
- desmopresin
- oral pharmaceutical
- jürgens
- hemophilia
- Prior art date
Links
- 239000008203 oral pharmaceutical composition Substances 0.000 title 1
- 102100026735 Coagulation factor VIII Human genes 0.000 abstract 1
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 abstract 1
- 201000003542 Factor VIII deficiency Diseases 0.000 abstract 1
- 208000009292 Hemophilia A Diseases 0.000 abstract 1
- 208000032843 Hemorrhage Diseases 0.000 abstract 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 abstract 1
- 208000004880 Polyuria Diseases 0.000 abstract 1
- 206010051077 Post procedural haemorrhage Diseases 0.000 abstract 1
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 abstract 1
- 229960004281 desmopressin Drugs 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000035619 diuresis Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000000422 nocturnal effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με μία υγρή από του στόματος φαρμακευτική σύνθεση δεσμοπρεσίνης, και τη χρήση της στη θεραπεία του κεντρικού άποιου διαβήτη, της πρόωρης νυχτερινής ενούρησης, της αιμορραγίας σε ασθενείς με Αιμοφιλία Α, με νόσο von Willebrand - Jürgens και της μετεγχειρητικής αιμορραγίας.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200702215A ES2319054B1 (es) | 2007-08-06 | 2007-08-06 | Composicion farmaceutica oral de desmopresina. |
PCT/ES2008/000539 WO2009027561A2 (es) | 2007-08-06 | 2008-08-01 | Composición farmacéutica oral de desmopresina |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118459T1 true CY1118459T1 (el) | 2017-07-12 |
Family
ID=40032884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20171100005T CY1118459T1 (el) | 2007-08-06 | 2017-01-03 | Απο του στοματος φαρμακευτικη συνθεση δεσμοπρεσινης |
Country Status (18)
Country | Link |
---|---|
US (1) | US8993521B2 (el) |
EP (1) | EP2174652B1 (el) |
JP (1) | JP5626682B2 (el) |
CN (2) | CN106265494A (el) |
AR (1) | AR068337A1 (el) |
BR (1) | BRPI0814835B8 (el) |
CY (1) | CY1118459T1 (el) |
DK (1) | DK2174652T3 (el) |
ES (2) | ES2319054B1 (el) |
HR (1) | HRP20161676T1 (el) |
HU (1) | HUE032667T2 (el) |
LT (1) | LT2174652T (el) |
MX (1) | MX2010001456A (el) |
PL (1) | PL2174652T3 (el) |
PT (1) | PT2174652T (el) |
RU (1) | RU2474414C2 (el) |
SI (1) | SI2174652T1 (el) |
WO (1) | WO2009027561A2 (el) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO3400B1 (ar) | 2010-09-30 | 2019-10-20 | Ferring Bv | مركب صيدلاني من كاربيتوسين |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8306367L (sv) | 1983-11-18 | 1985-05-19 | Ferring Ab | Antidiuretiskt verkande farmaceutiskt preparat |
ATE108326T1 (de) * | 1989-01-30 | 1994-07-15 | Corint Ltd | Wässerige desmopressin-cmc enthaltende arzneizubereitung. |
JP2653255B2 (ja) * | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
CA2070061C (en) | 1991-06-07 | 2004-02-10 | Shigeyuki Takama | Physiologically active polypeptide-containing pharmaceutical composition |
US5298256A (en) | 1992-04-28 | 1994-03-29 | Corint, Ltd. | Desmopressin buccal patch composition |
IT1255460B (it) | 1992-07-28 | 1995-11-02 | Poli Ind Chimica Spa | Composizioni farmaceutiche in forma di microemulsioni o di dispersioni liposomiali bioadesive per la somministrazione transmucosale di sostanze peptidiche e di proteine farmacologicamente attive |
SE9300937L (sv) | 1993-03-19 | 1994-09-20 | Anne Fjellestad Paulsen | Komposition för oral administrering av peptider |
US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
SE9400918L (sv) | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
US5763398A (en) * | 1996-06-20 | 1998-06-09 | Ferring B.V. | Nasal administration of desmopressin |
US20030095926A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract |
ES2297941T3 (es) * | 1998-11-02 | 2008-05-01 | Alza Corporation | Dispositivo de electrotransporte que comprende un agente antimicrobiano compatible. |
US6894026B1 (en) | 2000-01-11 | 2005-05-17 | Atossa Healthcare, Inc. | Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders |
EP1121935B1 (en) * | 2000-02-04 | 2008-08-13 | Patents Exploitation Company B.V. | Pharmaceutical composition containing a small or medium size peptide |
AT409081B (de) * | 2000-02-16 | 2002-05-27 | Gebro Pharma Gmbh | Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung |
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
AU2003269747A1 (en) * | 2002-05-15 | 2003-12-02 | Sun Pharmaceutical Industries Limited | A stable aqueous composition of a peptide |
ITMI20021684A1 (it) | 2002-07-29 | 2004-01-29 | Therapicon Srl | Composizione farmaceutica di peptide nasale |
EA012306B1 (ru) * | 2003-01-24 | 2009-08-28 | Магле Холдинг Аб | Композиционный материал для доставки через слизистые оболочки |
DE60300414T2 (de) | 2003-04-30 | 2006-05-11 | Ferring B.V. | Feste Dosierungsform mit Desmopressin |
ATE301990T1 (de) | 2003-07-25 | 2005-09-15 | Ferring Bv | Pharmazeutische desmopressin-zubereitung als feste darreichungsform und methode zu ihrer herstellung |
CN1878563A (zh) | 2003-11-10 | 2006-12-13 | 西摩·H·费恩 | 包含低剂量去氨加压素的药物组合物 |
GB0406048D0 (en) | 2004-03-18 | 2004-04-21 | Ardana Bioscience Ltd | Drug formulations |
US20050244502A1 (en) | 2004-04-28 | 2005-11-03 | Mathias Neil R | Composition for enhancing absorption of a drug and method |
-
2007
- 2007-08-06 ES ES200702215A patent/ES2319054B1/es active Active
-
2008
- 2008-08-01 RU RU2010105031/15A patent/RU2474414C2/ru active
- 2008-08-01 PT PT88053673T patent/PT2174652T/pt unknown
- 2008-08-01 HU HUE08805367A patent/HUE032667T2/en unknown
- 2008-08-01 MX MX2010001456A patent/MX2010001456A/es active IP Right Grant
- 2008-08-01 US US12/672,255 patent/US8993521B2/en active Active
- 2008-08-01 SI SI200831737A patent/SI2174652T1/sl unknown
- 2008-08-01 CN CN201610700664.8A patent/CN106265494A/zh active Pending
- 2008-08-01 LT LTEP08805367.3T patent/LT2174652T/lt unknown
- 2008-08-01 DK DK08805367.3T patent/DK2174652T3/en active
- 2008-08-01 PL PL08805367T patent/PL2174652T3/pl unknown
- 2008-08-01 EP EP08805367.3A patent/EP2174652B1/en active Active
- 2008-08-01 ES ES08805367.3T patent/ES2608816T3/es active Active
- 2008-08-01 WO PCT/ES2008/000539 patent/WO2009027561A2/es active Application Filing
- 2008-08-01 BR BRPI0814835A patent/BRPI0814835B8/pt not_active IP Right Cessation
- 2008-08-01 JP JP2010519481A patent/JP5626682B2/ja not_active Expired - Fee Related
- 2008-08-01 CN CN200880105631A patent/CN101808621A/zh active Pending
- 2008-08-06 AR ARP080103430A patent/AR068337A1/es not_active Application Discontinuation
-
2016
- 2016-12-08 HR HRP20161676TT patent/HRP20161676T1/hr unknown
-
2017
- 2017-01-03 CY CY20171100005T patent/CY1118459T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL2174652T3 (pl) | 2017-06-30 |
MX2010001456A (es) | 2010-06-02 |
PT2174652T (pt) | 2016-12-23 |
CN101808621A (zh) | 2010-08-18 |
JP2010535745A (ja) | 2010-11-25 |
BRPI0814835A2 (pt) | 2015-03-31 |
LT2174652T (lt) | 2017-02-27 |
EP2174652A2 (en) | 2010-04-14 |
AR068337A1 (es) | 2009-11-11 |
EP2174652B1 (en) | 2016-10-05 |
ES2319054A1 (es) | 2009-05-01 |
ES2608816T3 (es) | 2017-04-17 |
WO2009027561A3 (es) | 2009-07-16 |
JP5626682B2 (ja) | 2014-11-19 |
DK2174652T3 (en) | 2017-01-23 |
US20110251123A1 (en) | 2011-10-13 |
SI2174652T1 (sl) | 2017-04-26 |
HUE032667T2 (en) | 2017-10-30 |
BRPI0814835B1 (pt) | 2020-10-27 |
CN106265494A (zh) | 2017-01-04 |
RU2010105031A (ru) | 2011-09-20 |
BRPI0814835B8 (pt) | 2021-05-25 |
WO2009027561A2 (es) | 2009-03-05 |
ES2319054B1 (es) | 2010-02-12 |
HRP20161676T1 (hr) | 2017-02-24 |
RU2474414C2 (ru) | 2013-02-10 |
US8993521B2 (en) | 2015-03-31 |
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