CY1118393T1 - Τυποποιηση αντισωματος εναντι της il-17 - Google Patents

Τυποποιηση αντισωματος εναντι της il-17

Info

Publication number
CY1118393T1
CY1118393T1 CY20161101339T CY161101339T CY1118393T1 CY 1118393 T1 CY1118393 T1 CY 1118393T1 CY 20161101339 T CY20161101339 T CY 20161101339T CY 161101339 T CY161101339 T CY 161101339T CY 1118393 T1 CY1118393 T1 CY 1118393T1
Authority
CY
Cyprus
Prior art keywords
antibody
pharmaceutical formulations
standardization against
stabilized
antibody standardization
Prior art date
Application number
CY20161101339T
Other languages
Greek (el)
English (en)
Inventor
Vincent John Corvari
Barbara Ann Williams
Patrick Daniel Donovan
Aaron Paul Markham
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1118393T1 publication Critical patent/CY1118393T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY20161101339T 2012-03-07 2016-12-23 Τυποποιηση αντισωματος εναντι της il-17 CY1118393T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261607671P 2012-03-07 2012-03-07
PCT/US2013/028516 WO2013134052A1 (en) 2012-03-07 2013-03-01 Il-17 antibody formulation

Publications (1)

Publication Number Publication Date
CY1118393T1 true CY1118393T1 (el) 2017-06-28

Family

ID=47892018

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161101339T CY1118393T1 (el) 2012-03-07 2016-12-23 Τυποποιηση αντισωματος εναντι της il-17

Country Status (34)

Country Link
US (3) US9376491B2 (enExample)
EP (2) EP2822590B1 (enExample)
JP (1) JP6117252B2 (enExample)
KR (1) KR101653082B1 (enExample)
CN (1) CN104159612B (enExample)
AU (1) AU2013230490B2 (enExample)
BR (1) BR112014021308B1 (enExample)
CA (1) CA2866128C (enExample)
CL (1) CL2014002204A1 (enExample)
CY (1) CY1118393T1 (enExample)
DK (1) DK2822590T3 (enExample)
EA (1) EA030742B1 (enExample)
EC (1) ECSP14017562A (enExample)
ES (1) ES2610707T3 (enExample)
HR (1) HRP20161604T1 (enExample)
HU (1) HUE031290T2 (enExample)
IL (1) IL234053B (enExample)
LT (1) LT2822590T (enExample)
MA (1) MA37317B1 (enExample)
ME (1) ME02565B (enExample)
MX (1) MX362191B (enExample)
MY (1) MY167233A (enExample)
NZ (1) NZ627648A (enExample)
PE (1) PE20142275A1 (enExample)
PH (1) PH12014501985A1 (enExample)
PL (1) PL2822590T3 (enExample)
PT (1) PT2822590T (enExample)
RS (1) RS55417B1 (enExample)
SG (1) SG11201404491XA (enExample)
SI (1) SI2822590T1 (enExample)
TN (1) TN2014000341A1 (enExample)
UA (1) UA114620C2 (enExample)
WO (1) WO2013134052A1 (enExample)
ZA (1) ZA201405654B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR103173A1 (es) * 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
WO2018211517A1 (en) 2017-05-16 2018-11-22 Bhami's Research Laboratory, Pvt. Ltd. High concentration protein formulations with reduced viscosity
WO2019027828A1 (en) * 2017-08-04 2019-02-07 Eli Lilly And Company DOSAGE SCHEME OF ANTI-IL-17 ANTIBODIES
CN111032691A (zh) * 2017-08-23 2020-04-17 伊莱利利公司 生殖器银屑病的治疗
MX2017016884A (es) * 2017-12-19 2019-06-20 Probiomed S A De C V Formulacion farmaceutica estable de una proteina anti-tnfa.
AU2019388808A1 (en) * 2018-11-29 2021-06-17 Harbour Biomed Therapeutics Limited Anti-PD-L1 antibody preparation
SG11202108627SA (en) 2019-02-18 2021-09-29 Lilly Co Eli Therapeutic antibody formulation
CN112915201B (zh) * 2019-12-06 2023-06-27 珠海市丽珠单抗生物技术有限公司 包含抗il-17抗体的液体制剂
US20240052026A1 (en) * 2020-12-22 2024-02-15 Bio-Thera Solutions, Ltd. Stable antibody formulation, preparation method therefor, and applications thereof
CN119147687B (zh) * 2024-11-11 2025-03-14 智翔(上海)医药科技有限公司 用于抗白介素17a抗体质量检测的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101326195B9 (zh) * 2005-12-13 2022-11-11 伊莱利利公司 抗il-17抗体
MX2009005414A (es) * 2006-12-05 2009-06-01 Crucell Holland Bv Formulaciones liquidas de anticuerpo antirrabico.
SI3295957T1 (sl) * 2010-01-15 2020-02-28 Kirin-Amgen, Inc. Formulacija protitelesa proti IL-17RA in terapevtski režim za zdravljenje luskavice

Also Published As

Publication number Publication date
SI2822590T1 (sl) 2017-01-31
UA114620C2 (uk) 2017-07-10
NZ627648A (en) 2016-10-28
MX362191B (es) 2019-01-08
ES2610707T3 (es) 2017-05-03
HRP20161604T1 (hr) 2016-12-30
HUE031290T2 (hu) 2017-06-28
PT2822590T (pt) 2016-12-15
HK1199844A1 (en) 2015-07-24
LT2822590T (lt) 2017-01-25
ZA201405654B (en) 2016-05-25
IL234053A0 (en) 2014-09-30
EA030742B1 (ru) 2018-09-28
MA37317B1 (fr) 2016-10-31
SG11201404491XA (en) 2014-09-26
US10472416B2 (en) 2019-11-12
KR101653082B1 (ko) 2016-08-31
WO2013134052A1 (en) 2013-09-12
US9845353B2 (en) 2017-12-19
PL2822590T3 (pl) 2017-06-30
RS55417B1 (sr) 2017-04-28
ECSP14017562A (es) 2015-09-30
KR20140120938A (ko) 2014-10-14
IL234053B (en) 2018-06-28
CN104159612B (zh) 2016-03-16
US20180057584A1 (en) 2018-03-01
US9376491B2 (en) 2016-06-28
CA2866128A1 (en) 2013-09-12
US20150010573A1 (en) 2015-01-08
ME02565B (me) 2017-02-20
EA201491471A1 (ru) 2014-12-30
CA2866128C (en) 2017-02-28
DK2822590T3 (en) 2017-01-23
EP2822590B1 (en) 2016-10-26
CN104159612A (zh) 2014-11-19
MX2014010710A (es) 2015-04-14
EP3156073A1 (en) 2017-04-19
CL2014002204A1 (es) 2015-01-30
MY167233A (en) 2018-08-14
AU2013230490A1 (en) 2014-08-14
PE20142275A1 (es) 2015-01-08
JP6117252B2 (ja) 2017-04-19
AU2013230490B2 (en) 2017-04-13
BR112014021308B1 (pt) 2022-08-30
BR112014021308A2 (pt) 2017-07-04
PH12014501985B1 (en) 2014-11-24
PH12014501985A1 (en) 2014-11-24
TN2014000341A1 (en) 2015-12-21
EP2822590A1 (en) 2015-01-14
US20160280781A1 (en) 2016-09-29
JP2015510882A (ja) 2015-04-13
MA37317A1 (fr) 2016-03-31

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