ECSP14017562A - Formulación de anticuerpo il-17 - Google Patents

Formulación de anticuerpo il-17

Info

Publication number
ECSP14017562A
ECSP14017562A ECIEPI201417562A ECPI201417562A ECSP14017562A EC SP14017562 A ECSP14017562 A EC SP14017562A EC IEPI201417562 A ECIEPI201417562 A EC IEPI201417562A EC PI201417562 A ECPI201417562 A EC PI201417562A EC SP14017562 A ECSP14017562 A EC SP14017562A
Authority
EC
Ecuador
Prior art keywords
antibody formulation
pharmaceutical formulations
antibody
psoriasis
antibodies
Prior art date
Application number
ECIEPI201417562A
Other languages
English (en)
Inventor
Patrick Donovan
Aaron Markham
Barbara Williams
Vincent John Corvari
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP14017562A publication Critical patent/ECSP14017562A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a formulaciones farmacéuticas para anticuerpos anti-IL-17. Estas formulaciones farmacéuticas de anticuerpo anti-IL-17 pueden ser usadas para tratar artritis reumatoide, psoriasis, espondilitis anquilosante, artritis psoriática o mieloma múltiple.
ECIEPI201417562A 2012-03-07 2014-09-05 Formulación de anticuerpo il-17 ECSP14017562A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261607671P 2012-03-07 2012-03-07

Publications (1)

Publication Number Publication Date
ECSP14017562A true ECSP14017562A (es) 2015-09-30

Family

ID=47892018

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201417562A ECSP14017562A (es) 2012-03-07 2014-09-05 Formulación de anticuerpo il-17

Country Status (35)

Country Link
US (3) US9376491B2 (es)
EP (2) EP3156073A1 (es)
JP (1) JP6117252B2 (es)
KR (1) KR101653082B1 (es)
CN (1) CN104159612B (es)
AU (1) AU2013230490B2 (es)
BR (1) BR112014021308B1 (es)
CA (1) CA2866128C (es)
CL (1) CL2014002204A1 (es)
CY (1) CY1118393T1 (es)
DK (1) DK2822590T3 (es)
EA (1) EA030742B1 (es)
EC (1) ECSP14017562A (es)
ES (1) ES2610707T3 (es)
HK (1) HK1199844A1 (es)
HR (1) HRP20161604T1 (es)
HU (1) HUE031290T2 (es)
IL (1) IL234053B (es)
LT (1) LT2822590T (es)
MA (1) MA37317B1 (es)
ME (1) ME02565B (es)
MX (1) MX362191B (es)
MY (1) MY167233A (es)
NZ (1) NZ627648A (es)
PE (1) PE20142275A1 (es)
PH (1) PH12014501985B1 (es)
PL (1) PL2822590T3 (es)
PT (1) PT2822590T (es)
RS (1) RS55417B1 (es)
SG (1) SG11201404491XA (es)
SI (1) SI2822590T1 (es)
TN (1) TN2014000341A1 (es)
UA (1) UA114620C2 (es)
WO (1) WO2013134052A1 (es)
ZA (1) ZA201405654B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
WO2018211517A1 (en) 2017-05-16 2018-11-22 Bhami's Research Laboratory, Pvt. Ltd. High concentration protein formulations with reduced viscosity
WO2019027828A1 (en) * 2017-08-04 2019-02-07 Eli Lilly And Company DOSAGE SCHEME OF ANTI-IL-17 ANTIBODIES
JP7212675B2 (ja) 2017-08-23 2023-01-25 イーライ リリー アンド カンパニー 性器乾癬の治療
MX2017016884A (es) * 2017-12-19 2019-06-20 Probiomed S A De C V Formulacion farmaceutica estable de una proteina anti-tnfa.
WO2020108497A1 (zh) * 2018-11-29 2020-06-04 和铂医药(香港)有限公司 一种抗pd-l1抗体制剂
BR112021015034A2 (pt) 2019-02-18 2021-10-05 Eli Lilly And Company Formulação de anticorpo terapêutico
EP4268803A1 (en) * 2020-12-22 2023-11-01 Bio-Thera Solutions, Ltd. Stable antibody preparation, preparation method for same, and applications thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1963368E (pt) * 2005-12-13 2012-09-14 Lilly Co Eli Anticorpos anti-il-17
KR101522036B1 (ko) 2006-12-05 2015-05-20 크루셀 홀란드 비.브이. 액체 항-광견병 항체 조성물
HUE046670T2 (hu) * 2010-01-15 2020-03-30 Kirin Amgen Inc Anti IL-17RA ellenanyag kiszerelés és terápiás rendek pikkelysömör kezelésére

Also Published As

Publication number Publication date
CN104159612B (zh) 2016-03-16
PT2822590T (pt) 2016-12-15
DK2822590T3 (en) 2017-01-23
TN2014000341A1 (en) 2015-12-21
MA37317B1 (fr) 2016-10-31
EP3156073A1 (en) 2017-04-19
MY167233A (en) 2018-08-14
JP6117252B2 (ja) 2017-04-19
ES2610707T3 (es) 2017-05-03
KR101653082B1 (ko) 2016-08-31
HRP20161604T1 (hr) 2016-12-30
HUE031290T2 (hu) 2017-06-28
IL234053B (en) 2018-06-28
US9376491B2 (en) 2016-06-28
US20180057584A1 (en) 2018-03-01
WO2013134052A1 (en) 2013-09-12
HK1199844A1 (zh) 2015-07-24
PE20142275A1 (es) 2015-01-08
JP2015510882A (ja) 2015-04-13
SG11201404491XA (en) 2014-09-26
ME02565B (me) 2017-02-20
AU2013230490A1 (en) 2014-08-14
PH12014501985A1 (en) 2014-11-24
US9845353B2 (en) 2017-12-19
UA114620C2 (uk) 2017-07-10
BR112014021308B1 (pt) 2022-08-30
CA2866128C (en) 2017-02-28
EA030742B1 (ru) 2018-09-28
US20160280781A1 (en) 2016-09-29
EP2822590B1 (en) 2016-10-26
MX362191B (es) 2019-01-08
KR20140120938A (ko) 2014-10-14
CL2014002204A1 (es) 2015-01-30
NZ627648A (en) 2016-10-28
PH12014501985B1 (en) 2014-11-24
MX2014010710A (es) 2015-04-14
RS55417B1 (sr) 2017-04-28
CN104159612A (zh) 2014-11-19
PL2822590T3 (pl) 2017-06-30
IL234053A0 (en) 2014-09-30
BR112014021308A2 (pt) 2017-07-04
US20150010573A1 (en) 2015-01-08
CA2866128A1 (en) 2013-09-12
SI2822590T1 (sl) 2017-01-31
AU2013230490B2 (en) 2017-04-13
US10472416B2 (en) 2019-11-12
CY1118393T1 (el) 2017-06-28
MA37317A1 (fr) 2016-03-31
ZA201405654B (en) 2016-05-25
EP2822590A1 (en) 2015-01-14
EA201491471A1 (ru) 2014-12-30
LT2822590T (lt) 2017-01-25

Similar Documents

Publication Publication Date Title
ECSP14017562A (es) Formulación de anticuerpo il-17
EA201791422A1 (ru) Фармацевтические продукты и устойчивые жидкие композиции антител к il-17
CY1122956T1 (el) Αντισωματα εναντι αντιγονου 2 των δενδριτικων κυτταρων του αιματος και χρησεις αυτων
MX356337B (es) Anticuerpos contra csf-1r humano y sus usos.
PH12015502293A1 (en) Bispecific antibodies specific for fap and dr5, antibodies specific for dr5 and methods of use
CA2813849C (en) Secukinumab for use in the treatment of ankylosing spondylitis
BRPI0807710A8 (pt) Anticorpos que se ligam a il-23p19 e il-23 humana, anticorpo, ácido nucleico isolado, vetor de expressão, célula hospedeira microbiana, método de produção de um polipeptídeo e composição farmacêutica
CL2014001123A1 (es) Anticuerpos anti-il 36r; composicion farmaceutica que lo contiene; polinucleotido aislado que codifica el anticuerpo; metodo para la produccion del anticuerpo; kit de diagnostico que lo contiene.
PE20150002A1 (es) Anticuerpos anti-fcrn
AR094872A1 (es) Anticuerpos anti-tnf-anti-il-17 biespecíficos
CR20150153A (es) Tratamiento para artitris reumatoide
MX2016006101A (es) Agente ligante de la il-17a y usos del mismo.
EA201590412A1 (ru) Композиции антител и их применения
CO7111294A2 (es) Anticuerpo anti-fgfr2
EA201491622A1 (ru) Биспецифические антитела против baff и ил-17
UA117466C2 (uk) СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
FR3012725B1 (fr) Compositions d'agents de lutte biologique, leur procede de preparation et leurs utilisations
CU20170012A7 (es) Anticuerpos anti proteína similar a angiopoyetina 4
CL2021002816A1 (es) Usos de anticuerpos anti-il-17a/f (divisional 2018-01135)
BR112016029460A2 (pt) métodos para tratar artrite reumatoide
EP3560956A3 (en) Methods of treating inflammatory diseases
AR089079A1 (es) Formulacion de anticuerpo anti-cd44
TN2013000145A1 (en) Methods of treating psoriasis using il-17 antagonists
TH159903A (th) สูตรผสมแอนติบอดี il-17
NZ743656A (en) Methods of treating a tauopathy