HK1199844A1 - 抗體配方 - Google Patents

抗體配方

Info

Publication number
HK1199844A1
HK1199844A1 HK15100440.9A HK15100440A HK1199844A1 HK 1199844 A1 HK1199844 A1 HK 1199844A1 HK 15100440 A HK15100440 A HK 15100440A HK 1199844 A1 HK1199844 A1 HK 1199844A1
Authority
HK
Hong Kong
Prior art keywords
antibody formulation
antibody
formulation
Prior art date
Application number
HK15100440.9A
Other languages
English (en)
Inventor
Vincent John Corvari
Barbara Ann Williams
Patrick Daniel Donovan
Aaron Paul Markham
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1199844A1 publication Critical patent/HK1199844A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15100440.9A 2012-03-07 2015-01-15 抗體配方 HK1199844A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261607671P 2012-03-07 2012-03-07
PCT/US2013/028516 WO2013134052A1 (en) 2012-03-07 2013-03-01 Il-17 antibody formulation

Publications (1)

Publication Number Publication Date
HK1199844A1 true HK1199844A1 (zh) 2015-07-24

Family

ID=47892018

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15100440.9A HK1199844A1 (zh) 2012-03-07 2015-01-15 抗體配方

Country Status (35)

Country Link
US (3) US9376491B2 (zh)
EP (2) EP2822590B1 (zh)
JP (1) JP6117252B2 (zh)
KR (1) KR101653082B1 (zh)
CN (1) CN104159612B (zh)
AU (1) AU2013230490B2 (zh)
BR (1) BR112014021308B1 (zh)
CA (1) CA2866128C (zh)
CL (1) CL2014002204A1 (zh)
CY (1) CY1118393T1 (zh)
DK (1) DK2822590T3 (zh)
EA (1) EA030742B1 (zh)
EC (1) ECSP14017562A (zh)
ES (1) ES2610707T3 (zh)
HK (1) HK1199844A1 (zh)
HR (1) HRP20161604T1 (zh)
HU (1) HUE031290T2 (zh)
IL (1) IL234053B (zh)
LT (1) LT2822590T (zh)
MA (1) MA37317B1 (zh)
ME (1) ME02565B (zh)
MX (1) MX362191B (zh)
MY (1) MY167233A (zh)
NZ (1) NZ627648A (zh)
PE (1) PE20142275A1 (zh)
PH (1) PH12014501985B1 (zh)
PL (1) PL2822590T3 (zh)
PT (1) PT2822590T (zh)
RS (1) RS55417B1 (zh)
SG (1) SG11201404491XA (zh)
SI (1) SI2822590T1 (zh)
TN (1) TN2014000341A1 (zh)
UA (1) UA114620C2 (zh)
WO (1) WO2013134052A1 (zh)
ZA (1) ZA201405654B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
US10646569B2 (en) 2017-05-16 2020-05-12 Bhami's Research Laboratory, Pvt. Ltd. High concentration protein formulations with reduced viscosity
WO2019027828A1 (en) 2017-08-04 2019-02-07 Eli Lilly And Company DOSAGE SCHEME OF ANTI-IL-17 ANTIBODIES
CA3073597A1 (en) 2017-08-23 2019-02-28 Eli Lilly And Company Treatment of genital psoriasis
MX2017016884A (es) * 2017-12-19 2019-06-20 Probiomed S A De C V Formulacion farmaceutica estable de una proteina anti-tnfa.
US20230287122A1 (en) * 2018-11-29 2023-09-14 Harbour Biomed Therapeutics Limited Anti-pd-l1 antibody preparation
JP7266108B2 (ja) 2019-02-18 2023-04-27 イーライ リリー アンド カンパニー 治療用抗体製剤
EP4268803A1 (en) * 2020-12-22 2023-11-01 Bio-Thera Solutions, Ltd. Stable antibody preparation, preparation method for same, and applications thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2481753T3 (pl) * 2005-12-13 2018-09-28 Eli Lilly And Company Przeciwciała anty-IL-17
CA2668947C (en) * 2006-12-05 2017-02-07 Crucell Holland B.V. Liquid anti-rabies antibody formulations
CN102821787B (zh) * 2010-01-15 2015-07-29 麒麟-安姆根有限公司 抗体制剂和治疗方案

Also Published As

Publication number Publication date
ES2610707T3 (es) 2017-05-03
SG11201404491XA (en) 2014-09-26
CA2866128A1 (en) 2013-09-12
JP2015510882A (ja) 2015-04-13
RS55417B1 (sr) 2017-04-28
MA37317A1 (fr) 2016-03-31
CL2014002204A1 (es) 2015-01-30
MX2014010710A (es) 2015-04-14
JP6117252B2 (ja) 2017-04-19
MY167233A (en) 2018-08-14
CA2866128C (en) 2017-02-28
US9376491B2 (en) 2016-06-28
PT2822590T (pt) 2016-12-15
CN104159612B (zh) 2016-03-16
KR101653082B1 (ko) 2016-08-31
DK2822590T3 (en) 2017-01-23
UA114620C2 (uk) 2017-07-10
US20180057584A1 (en) 2018-03-01
LT2822590T (lt) 2017-01-25
MX362191B (es) 2019-01-08
PH12014501985A1 (en) 2014-11-24
IL234053B (en) 2018-06-28
ME02565B (me) 2017-02-20
WO2013134052A1 (en) 2013-09-12
PH12014501985B1 (en) 2014-11-24
CY1118393T1 (el) 2017-06-28
BR112014021308A2 (pt) 2017-07-04
PL2822590T3 (pl) 2017-06-30
US20150010573A1 (en) 2015-01-08
IL234053A0 (en) 2014-09-30
ECSP14017562A (es) 2015-09-30
PE20142275A1 (es) 2015-01-08
HRP20161604T1 (hr) 2016-12-30
HUE031290T2 (hu) 2017-06-28
TN2014000341A1 (en) 2015-12-21
EA030742B1 (ru) 2018-09-28
CN104159612A (zh) 2014-11-19
US10472416B2 (en) 2019-11-12
EA201491471A1 (ru) 2014-12-30
ZA201405654B (en) 2016-05-25
EP2822590B1 (en) 2016-10-26
NZ627648A (en) 2016-10-28
KR20140120938A (ko) 2014-10-14
US20160280781A1 (en) 2016-09-29
AU2013230490B2 (en) 2017-04-13
AU2013230490A1 (en) 2014-08-14
SI2822590T1 (sl) 2017-01-31
EP2822590A1 (en) 2015-01-14
US9845353B2 (en) 2017-12-19
BR112014021308B1 (pt) 2022-08-30
MA37317B1 (fr) 2016-10-31
EP3156073A1 (en) 2017-04-19

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