CY1115731T1 - Παραγοντας αναστολης toy mic-1 - Google Patents
Παραγοντας αναστολης toy mic-1Info
- Publication number
- CY1115731T1 CY1115731T1 CY20141100862T CY141100862T CY1115731T1 CY 1115731 T1 CY1115731 T1 CY 1115731T1 CY 20141100862 T CY20141100862 T CY 20141100862T CY 141100862 T CY141100862 T CY 141100862T CY 1115731 T1 CY1115731 T1 CY 1115731T1
- Authority
- CY
- Cyprus
- Prior art keywords
- mic
- toy
- subject
- present
- suspension factor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/02—Nutritional disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/303—Eating disorders, e.g. anorexia, bulimia
Abstract
Η παρούσα εφεύρεση σχετίζεται με μια μέθοδο ελέγχου της όρεξης και/ή του σωματικού βάρους σε ένα υποκείμενο, με την εν λόγω μέθοδο να περιλαμβάνει χορήγηση στο εν λόγω υποκείμενο μιας αποτελεσματικής ποσότητας παράγοντα ρύθμισης του MIC-1, όπου ο εν λόγω παράγοντας αυξάνει ή μειώνει την ποσότητα του MIC-1 που υπάρχει στο εν λόγω υποκείμενο, ή αναστέλλει ή ενισχύει την βιολογική ενεργότητα του MIC-1 που υπάρχει στο εν λόγω δείγμα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2004901957A AU2004901957A0 (en) | 2004-04-13 | Method for modulating appetite | |
EP11183884.3A EP2441466B1 (en) | 2004-04-13 | 2005-04-13 | MIC-1 inhibiting agent |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1115731T1 true CY1115731T1 (el) | 2017-01-25 |
Family
ID=35149777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100862T CY1115731T1 (el) | 2004-04-13 | 2014-10-22 | Παραγοντας αναστολης toy mic-1 |
Country Status (12)
Country | Link |
---|---|
US (6) | US8192735B2 (el) |
EP (4) | EP1734986B1 (el) |
JP (4) | JP5448338B2 (el) |
CA (2) | CA2905125C (el) |
CY (1) | CY1115731T1 (el) |
DK (2) | DK2929891T3 (el) |
ES (3) | ES2788868T3 (el) |
HK (2) | HK1168274A1 (el) |
PL (2) | PL2929891T3 (el) |
PT (2) | PT2441466E (el) |
SI (1) | SI2441466T1 (el) |
WO (1) | WO2005099746A1 (el) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5448338B2 (ja) * | 2004-04-13 | 2014-03-19 | セントビンセンツ ホスピタル シドニー リミテッド | 食欲を調節する方法 |
JP5309026B2 (ja) * | 2006-08-04 | 2013-10-09 | メディツィニッシュ ホホシュール ハノーバー | Gdf−15に基づく心臓インターベンションの危険性を評価するための手段および方法 |
US20100278843A1 (en) * | 2007-08-16 | 2010-11-04 | St. Vincent's Hospital Sydney Limited | Agents and methods for modulating macrophage inhibitory cytokine (mic-1) activity |
CN101896192A (zh) * | 2007-10-09 | 2010-11-24 | 圣文森特医院悉尼有限公司 | 一种通过去除或灭活巨噬细胞抑制因子-1而治疗恶病质的方法 |
ES2434996T3 (es) * | 2008-10-31 | 2013-12-18 | St Vincent's Hospital Sydney Limited | Métodos de pronóstico en enfermedad renal crónica |
WO2012138919A2 (en) | 2011-04-08 | 2012-10-11 | Amgen Inc. | Method of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15) |
EP3683228A3 (en) | 2012-01-26 | 2020-07-29 | Amgen Inc. | Growth differentiation factor 15 (gdf-15) polypeptides |
US9550819B2 (en) | 2012-03-27 | 2017-01-24 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
US20150239968A1 (en) | 2012-09-26 | 2015-08-27 | Julius-Maximilians-Universität Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (gdf-15) |
DK2934584T3 (da) * | 2012-12-21 | 2020-05-18 | Aveo Pharmaceuticals Inc | Anti-gdf15-antistoffer |
US9161966B2 (en) | 2013-01-30 | 2015-10-20 | Ngm Biopharmaceuticals, Inc. | GDF15 mutein polypeptides |
CA2899170C (en) | 2013-01-30 | 2022-08-02 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use in treating metabolic disorders |
LT3027642T (lt) | 2013-07-31 | 2020-10-12 | Amgen Inc. | Augimo ir diferenciacijos faktoriaus 15(gdf-15) konstruktai |
GB2524552B (en) * | 2014-03-26 | 2017-07-12 | Julius-Maximilians-Universitãt Wurzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and use thereof for treating cancer |
GB2524553C (en) * | 2014-03-26 | 2017-07-19 | Julius-Maximilians-Universitãt Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia |
HUE047398T2 (hu) * | 2014-03-26 | 2020-04-28 | Univ Wuerzburg J Maximilians | Növekedési és differenciálódási faktor 15 (GDF-15) elleni monoklonális antitestek és azok alkalmazásai rákos sorvadás és rák kezelésére |
US20170137505A1 (en) * | 2014-06-20 | 2017-05-18 | Aveo Pharmaceuticals, Inc. | Treatment of congestive heart failure and other cardiac dysfunction using a gdf15 modulator |
BR112016029820A2 (pt) * | 2014-06-20 | 2017-10-24 | Aveo Pharmaceuticals Inc | tratamento de doença renal crônica e outras disfunções renais usando um modulador de gdf15 |
EP3157942B1 (en) * | 2014-06-23 | 2020-06-17 | Novartis AG | Site specific protein modifications |
US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
EP3160496B1 (en) | 2014-06-24 | 2021-03-03 | Novo Nordisk As | MIC-1 FUSION PROTEINS AND RELATED USES |
WO2016018931A1 (en) | 2014-07-30 | 2016-02-04 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
US20170306008A1 (en) * | 2014-09-25 | 2017-10-26 | Aveo Pharmaceuticals, Inc. | Methods of reversing cachexia and prolonging survival comprising administering a gdf15 modulator and an anti-cancer agent |
AU2015339130C1 (en) | 2014-10-31 | 2021-03-18 | Ngm Biopharmaceuticals, Inc. | Compositions and methods of use for treating metabolic disorders |
CN107108754A (zh) * | 2014-12-22 | 2017-08-29 | 诺和诺德股份有限公司 | α‑1‑抗胰蛋白酶(A1AT)融合蛋白及其用途 |
EP4321866A3 (en) | 2015-10-02 | 2024-03-20 | Julius-Maximilians-Universität Würzburg | Gdf-15 as a diagnostic marker to predict the clinical outcome of a treatment with immune checkpoint blockers |
GB201517528D0 (en) | 2015-10-02 | 2015-11-18 | Julius Maximillians Universitãt Würzburg | GDF-15 as a diagnosis marker for melanoma |
KR20180054868A (ko) | 2015-10-02 | 2018-05-24 | 율리우스-막시밀리안스 우니버지태트 뷔르츠부르크 | 인간 증식 및 분화 인자 15 (gdf-15)의 저해제와 면역 체크포인트 차단제를 이용한 병용 요법 |
US11105818B2 (en) | 2016-01-15 | 2021-08-31 | Novo Nordisk A/S | MIC-1 receptor and uses thereof |
CN108700573B (zh) * | 2016-02-29 | 2021-06-11 | 公立大学法人横滨市立大学 | 检测去势抵抗性前列腺癌的方法和检测试剂 |
PE20190126A1 (es) | 2016-03-31 | 2019-01-17 | Ngm Biopharmaceuticals Inc | Proteinas de union y metodos de uso de las mismas |
CN109071647B (zh) | 2016-04-27 | 2022-11-22 | 诺华股份有限公司 | 抗生长分化因子15的抗体及其用途 |
MA46523A (fr) * | 2016-10-12 | 2019-08-21 | Janssen Biotech Inc | Procédés de criblage de modulateurs d'une activité biologique de type gdf15 |
JP7134960B2 (ja) * | 2016-12-06 | 2022-09-12 | セントビンセンツ ホスピタル シドニー リミテッド | 肥満及び摂食障害の治療 |
GB201700567D0 (en) | 2017-01-12 | 2017-03-01 | Genagon Therapeutics Ab | Therapeutic agents |
TWI710377B (zh) | 2017-05-23 | 2020-11-21 | 丹麥商諾佛 儂迪克股份有限公司 | Mic-1化合物及其用途 |
WO2019004550A1 (ko) * | 2017-06-26 | 2019-01-03 | 강원대학교 산학협력단 | Mic-1 단백질에 특이적으로 결합하는 항체 및 이의 용도 |
JP7127422B2 (ja) * | 2017-08-30 | 2022-08-30 | 東ソー株式会社 | 癌を検出する方法及び検出試薬 |
JP2020533302A (ja) | 2017-09-10 | 2020-11-19 | ノヴォ ノルディスク アー/エス | 肥満の治療において使用するためのmic−1およびglp−1 |
PE20201350A1 (es) | 2018-04-09 | 2020-11-30 | Amgen Inc | Proteinas de fusion del factor de diferenciacion de crecimiento 15 |
BR112021003173A2 (pt) | 2018-08-20 | 2021-05-11 | Pfizer Inc. | anticorpos anti-gdf15, composições e métodos de uso |
US11810670B2 (en) | 2018-11-13 | 2023-11-07 | CurieAI, Inc. | Intelligent health monitoring |
EP4065597A4 (en) | 2019-11-26 | 2024-01-24 | Yuhan Corp | LONG-ACTING GDF15 FUSION PROTEINS AND PHARMACEUTICAL COMPOSITION THEREFROM |
EP4314071A1 (en) | 2021-03-31 | 2024-02-07 | Cambridge Enterprise Limited | Therapeutic inhibitors of gdf15 signalling |
CA3219645A1 (en) | 2021-05-21 | 2022-11-24 | Yuhan Corporation | Composition for combination therapy comprising growth differentiation factor-15 variant and glucagon-like peptide-1 receptor agonist |
KR20220157911A (ko) | 2021-05-21 | 2022-11-29 | 주식회사유한양행 | Gdf15 변이체를 포함하는 비알코올성 지방간질환 또는 비알코올성 지방간염의 예방 또는 치료용 조성물 |
IL310535A (en) | 2021-08-10 | 2024-03-01 | Byomass Inc | Anti-GDF15 antibodies, compositions and uses thereof |
WO2023122213A1 (en) | 2021-12-22 | 2023-06-29 | Byomass Inc. | Targeting gdf15-gfral pathway cross-reference to related applications |
WO2023154953A1 (en) | 2022-02-14 | 2023-08-17 | Ngm Biopharmaceuticals, Inc. | Gdf15 polypeptides for treating and preventing autoimmune diseases |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
WO1997000958A1 (en) | 1995-06-22 | 1997-01-09 | St. Vincent's Hospital Sydney Limited | NOVEL TGF-β LIKE CYTOKINE |
WO1999006445A1 (en) * | 1997-07-31 | 1999-02-11 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-15 |
EP1117805A2 (en) | 1998-10-07 | 2001-07-25 | STRYKER CORPORATION (a Michigan corporation) | Modified tgf-beta superfamily proteins |
DE60142372D1 (de) | 2000-04-20 | 2010-07-22 | St Vincents Hosp Sydney | Diagnostischer Assay mit makrophagenhemmendem Zytokin-1 (MIC-1) |
US7141661B2 (en) * | 2000-09-08 | 2006-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties |
US7157235B2 (en) * | 2002-06-17 | 2007-01-02 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
JP5448338B2 (ja) | 2004-04-13 | 2014-03-19 | セントビンセンツ ホスピタル シドニー リミテッド | 食欲を調節する方法 |
WO2006078161A1 (en) * | 2005-01-24 | 2006-07-27 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
EP2396025A2 (en) | 2009-02-12 | 2011-12-21 | Stryker Corporation | Peripheral administration of proteins including tgf-beta superfamily members for systemic treatment of disorders and disease |
-
2005
- 2005-04-13 JP JP2007507619A patent/JP5448338B2/ja active Active
- 2005-04-13 ES ES15163748T patent/ES2788868T3/es active Active
- 2005-04-13 EP EP05729508.1A patent/EP1734986B1/en active Active
- 2005-04-13 EP EP14171119.2A patent/EP2774620A1/en not_active Withdrawn
- 2005-04-13 US US11/547,675 patent/US8192735B2/en active Active
- 2005-04-13 PT PT111838843T patent/PT2441466E/pt unknown
- 2005-04-13 DK DK15163748.5T patent/DK2929891T3/da active
- 2005-04-13 PL PL15163748T patent/PL2929891T3/pl unknown
- 2005-04-13 ES ES11183884.3T patent/ES2518865T3/es active Active
- 2005-04-13 SI SI200531902T patent/SI2441466T1/sl unknown
- 2005-04-13 CA CA2905125A patent/CA2905125C/en active Active
- 2005-04-13 ES ES05729508.1T patent/ES2555956T3/es active Active
- 2005-04-13 EP EP15163748.5A patent/EP2929891B1/en active Active
- 2005-04-13 DK DK11183884.3T patent/DK2441466T3/da active
- 2005-04-13 PL PL11183884T patent/PL2441466T3/pl unknown
- 2005-04-13 CA CA2561877A patent/CA2561877C/en active Active
- 2005-04-13 PT PT151637485T patent/PT2929891T/pt unknown
- 2005-04-13 WO PCT/AU2005/000525 patent/WO2005099746A1/en not_active Application Discontinuation
- 2005-04-13 EP EP11183884.3A patent/EP2441466B1/en active Active
-
2007
- 2007-05-23 HK HK12108474.4A patent/HK1168274A1/xx unknown
- 2007-05-23 HK HK16103907.8A patent/HK1215932A1/zh unknown
-
2010
- 2010-11-05 US US12/926,272 patent/US8946146B2/en active Active
-
2011
- 2011-04-08 JP JP2011086143A patent/JP2011190262A/ja active Pending
-
2013
- 2013-04-16 JP JP2013086022A patent/JP5767667B2/ja active Active
- 2013-10-22 JP JP2013219147A patent/JP5806275B2/ja active Active
-
2014
- 2014-10-22 CY CY20141100862T patent/CY1115731T1/el unknown
- 2014-12-22 US US14/578,611 patent/US20150183861A1/en not_active Abandoned
-
2016
- 2016-06-02 US US15/171,693 patent/US20160289320A1/en not_active Abandoned
-
2018
- 2018-06-11 US US16/004,519 patent/US20180346560A1/en not_active Abandoned
-
2020
- 2020-12-15 US US17/247,515 patent/US20210340243A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1115731T1 (el) | Παραγοντας αναστολης toy mic-1 | |
CY1121162T1 (el) | M-csf-ειδικο μονοκλωνικο αντισωμα και χρησεις αυτου | |
CY1112383T1 (el) | Αναστολεις της πρωτεϊνης ενεργοποιησης της 5-λιποξυγενασης (flap) | |
CY1119598T1 (el) | Ανθεκτικες σε θραυση μορφες δοσολογησης με επιβραδυντικη απελευθερωση | |
CY1120434T1 (el) | Πρωτεϊνες προσδεσης il-1 | |
CY1120384T1 (el) | Απταμερη θεραπευτικα χρησιμα στην αντιμετωπιση των σχετικων με το συμπληρωμα διαταραχων | |
CY1118472T1 (el) | Υποκατεστημενα ακυλανιλιδια και μεθοδοι χρησης αυτων | |
ME00380B (me) | Amtagonisti aktivin-actriia i primjene za stimulaciju rasta kosti | |
CY1115860T1 (el) | Χρηση hif αλφα σταθεροποιητων για ενισχυση της ερυθροποιησης | |
ATE527365T1 (de) | Il-15r alpha -sushi domäne als selektiver und effizienter verstärker der il-15-wirkung durch il-15rbeta/gamma , in hyperagonist il-15 ralpha sushi -il 15 fusionsproteine . | |
CY1111714T1 (el) | Δεσμευτικες πρωτεϊνες αυξητικου παραγοντα ηπατοκυτταρων (hgf). | |
DK1487856T3 (da) | KDR-specifikke humane antistoffer og deres anvendelse | |
DE602005021694D1 (de) | Kombinationstherapien gegen multiple toll-like-rezeptoren und ihre verwendung | |
CY1115437T1 (el) | Υδροξυμεθυλοκυκλοεξυλαμινες | |
CY1111354T1 (el) | Συστασεις αναστολεα ddp iv | |
ATE474578T1 (de) | Verwendung von flibanserin bei der behandlung von prämenstruellen störungen | |
NL1026829A1 (nl) | Gemodificeerde humane IGF-1R-antilichamen. | |
ECSP077222A (es) | Anticuerpos monoclonales humanos contra interleucina-4 humana (il-4) | |
DE60314500D1 (de) | Diaminopyrimidine und deren verwendung als angiogenesehemmer | |
CY2014007I2 (el) | Μεθοδοι για την αγωγη διαταραχων ή παθησεων που συσχετιζονται με υπερλιπιδαιμια και υπερχοληστερολαιμια ενω ελαχιστοποιουνται οι παρενεργειες | |
ATE395082T1 (de) | Antikörper gegen krebsantigen tmeff2 und seine anwendungen | |
DE602004019995D1 (de) | Verwendung von n-arylhydrazinderivaten für die bekämpfung von schädlingen in und an tieren | |
TR201901390T4 (tr) | Demodikoza karşı madde. | |
ATE497737T1 (de) | Implantate beschichtet mit aptameren, die die adhäsion von endothelialen vorläuferzellen vermitteln | |
CY1113310T1 (el) | Εξανθρωπισμενα αντισωματα ειδικα για nogo-a και φαρμακευτικες χρησεις αυτων |