ATE395082T1 - Antikörper gegen krebsantigen tmeff2 und seine anwendungen - Google Patents
Antikörper gegen krebsantigen tmeff2 und seine anwendungenInfo
- Publication number
- ATE395082T1 ATE395082T1 AT03744243T AT03744243T ATE395082T1 AT E395082 T1 ATE395082 T1 AT E395082T1 AT 03744243 T AT03744243 T AT 03744243T AT 03744243 T AT03744243 T AT 03744243T AT E395082 T1 ATE395082 T1 AT E395082T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- applications
- cancer antigen
- tmeff2
- antigen tmeff2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pregnancy & Childbirth (AREA)
- Toxicology (AREA)
- Gynecology & Obstetrics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36283702P | 2002-03-08 | 2002-03-08 | |
| US43681202P | 2002-12-27 | 2002-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE395082T1 true ATE395082T1 (de) | 2008-05-15 |
Family
ID=27807977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03744243T ATE395082T1 (de) | 2002-03-08 | 2003-03-07 | Antikörper gegen krebsantigen tmeff2 und seine anwendungen |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US7288248B2 (de) |
| EP (1) | EP1572087B1 (de) |
| JP (2) | JP2006502092A (de) |
| KR (1) | KR101104655B1 (de) |
| AT (1) | ATE395082T1 (de) |
| AU (1) | AU2003252830B2 (de) |
| CA (1) | CA2478683C (de) |
| DE (1) | DE60321041D1 (de) |
| DK (1) | DK1572087T3 (de) |
| ES (1) | ES2305481T3 (de) |
| IL (1) | IL163902A0 (de) |
| PT (1) | PT1572087E (de) |
| SI (1) | SI1572087T1 (de) |
| WO (1) | WO2003075855A2 (de) |
| ZA (1) | ZA200407733B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996036709A1 (en) * | 1995-05-19 | 1996-11-21 | Human Genome Sciences, Inc. | Transforming growth factor alpha hii |
| US20040141983A1 (en) * | 1999-03-15 | 2004-07-22 | Protein Design Labs, Inc. | Compositions against cancer antigen LIV-1 and uses thereof |
| KR101104655B1 (ko) * | 2002-03-08 | 2012-01-13 | 애보트 바이오테라퓨틱스 코포레이션 | 암 항원 ｔｍｅｆｆ２ 에 대한 항체 및 이의 용도 |
| US20030180348A1 (en) * | 2002-03-22 | 2003-09-25 | Levinson R. Saul | Transcellular drug delivery system |
| US20050276812A1 (en) * | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody-drug conjugates and methods |
| DK1545613T3 (da) * | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| WO2004067564A2 (en) * | 2003-01-29 | 2004-08-12 | Protein Design Labs, Inc. | Compositions against cancer antigen liv-1 and uses thereof |
| CN107213469A (zh) | 2003-11-06 | 2017-09-29 | 西雅图基因公司 | 能够与配体偶联的单甲基缬氨酸化合物 |
| US20050175619A1 (en) * | 2004-02-05 | 2005-08-11 | Robert Duffy | Methods of producing antibody conjugates |
| EP1907001B1 (de) | 2005-06-17 | 2015-07-15 | Merck Sharp & Dohme Corp. | Ilt3-bindungsmoleküle und ihre verwendungen |
| US20060292074A1 (en) * | 2005-06-28 | 2006-12-28 | Schering Aktiengesellschaft | Tomoregulin antibodies and uses thereof |
| CA2655903A1 (en) | 2006-06-19 | 2008-08-07 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
| JP2010517910A (ja) * | 2007-02-05 | 2010-05-27 | エレメント シックス （プロダクション）（プロプライエタリィ） リミテッド | 多結晶ダイヤモンド（ｐｃｄ）材料 |
| CL2008002083A1 (es) | 2007-07-16 | 2008-11-21 | Genentech Inc | Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico |
| NZ583367A (en) | 2007-07-16 | 2012-10-26 | Genentech Inc | Anti-cd79b antibodies and immunoconjugates and methods of use |
| CA2698541C (en) * | 2007-10-19 | 2018-01-09 | Genentech, Inc. | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
| ES2643239T3 (es) | 2008-01-31 | 2017-11-21 | Genentech, Inc. | Anticuerpos anti-CD79b e inmunoconjugados y métodos de uso |
| DK2385992T3 (en) * | 2009-01-07 | 2015-04-07 | Arcedi Biotech Aps | Enriching and identifying fetal cells in maternal blood and ligand for such use |
| WO2011082187A1 (en) | 2009-12-30 | 2011-07-07 | Genentech, Inc. | Methods for modulating a pdgf-aa mediated biological response |
| MX379481B (es) | 2010-12-06 | 2025-03-11 | Seagen Inc | Anticuerpos humanizados a liv-1 y uso de los mismos para tratar cancer |
| WO2013093122A2 (en) * | 2011-12-23 | 2013-06-27 | Phenoquest Ag | Antibodies for the treatment and diagnosis of affective and anxiety disorders |
| DK3262071T3 (da) | 2014-09-23 | 2020-06-15 | Hoffmann La Roche | Fremgangsmåde til anvendelse af anti-CD79b-immunkonjugater |
| KR20220157515A (ko) | 2016-03-15 | 2022-11-29 | 씨젠 인크. | Liv1-adc와 화학요법제를 사용한 병용 요법 |
| MA52772A (fr) * | 2018-05-24 | 2021-04-14 | Janssen Biotech Inc | Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations |
| UA128273C2 (uk) | 2019-06-07 | 2024-05-22 | Арседі Байотек Апс | Спосіб пренатальної діагностики (варанти) |
| KR20230142482A (ko) * | 2021-01-27 | 2023-10-11 | 얀센 바이오테크 인코포레이티드 | 칼리크레인 관련 펩티다제 2 항원 결합 도메인을 포함하는면역접합체 및 이의 용도 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101104655B1 (ko) * | 2002-03-08 | 2012-01-13 | 애보트 바이오테라퓨틱스 코포레이션 | 암 항원 ｔｍｅｆｆ２ 에 대한 항체 및 이의 용도 |
-
2003
- 2003-03-07 KR KR1020047014105A patent/KR101104655B1/ko not_active Expired - Fee Related
- 2003-03-07 JP JP2003574131A patent/JP2006502092A/ja not_active Withdrawn
- 2003-03-07 CA CA2478683A patent/CA2478683C/en not_active Expired - Lifetime
- 2003-03-07 DK DK03744243T patent/DK1572087T3/da active
- 2003-03-07 AT AT03744243T patent/ATE395082T1/de active
- 2003-03-07 WO PCT/US2003/007209 patent/WO2003075855A2/en not_active Ceased
- 2003-03-07 SI SI200331266T patent/SI1572087T1/sl unknown
- 2003-03-07 PT PT03744243T patent/PT1572087E/pt unknown
- 2003-03-07 IL IL16390203A patent/IL163902A0/xx active IP Right Grant
- 2003-03-07 ES ES03744243T patent/ES2305481T3/es not_active Expired - Lifetime
- 2003-03-07 US US10/383,447 patent/US7288248B2/en not_active Expired - Lifetime
- 2003-03-07 AU AU2003252830A patent/AU2003252830B2/en not_active Ceased
- 2003-03-07 DE DE60321041T patent/DE60321041D1/de not_active Expired - Lifetime
- 2003-03-07 EP EP03744243A patent/EP1572087B1/de not_active Expired - Lifetime
-
2004
- 2004-09-23 ZA ZA2004/07733A patent/ZA200407733B/en unknown
-
2007
- 2007-08-10 US US11/837,337 patent/US7824678B2/en not_active Expired - Lifetime
- 2007-08-10 US US11/837,333 patent/US7785816B2/en not_active Expired - Fee Related
- 2007-09-13 US US11/855,073 patent/US7674883B2/en not_active Expired - Lifetime
-
2010
- 2010-09-28 US US12/892,725 patent/US8257708B2/en not_active Expired - Fee Related
- 2010-12-16 JP JP2010280694A patent/JP5192537B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7824678B2 (en) | 2010-11-02 |
| JP2006502092A (ja) | 2006-01-19 |
| KR101104655B1 (ko) | 2012-01-13 |
| JP2011121950A (ja) | 2011-06-23 |
| WO2003075855A2 (en) | 2003-09-18 |
| IL163902A0 (en) | 2005-12-18 |
| US7785816B2 (en) | 2010-08-31 |
| AU2003252830A1 (en) | 2003-09-22 |
| US20080044840A1 (en) | 2008-02-21 |
| US7288248B2 (en) | 2007-10-30 |
| CA2478683A1 (en) | 2003-09-18 |
| US7674883B2 (en) | 2010-03-09 |
| ZA200407733B (en) | 2005-10-26 |
| EP1572087B1 (de) | 2008-05-14 |
| DE60321041D1 (de) | 2008-06-26 |
| WO2003075855A3 (en) | 2006-03-23 |
| SI1572087T1 (sl) | 2008-10-31 |
| US20080175846A1 (en) | 2008-07-24 |
| EP1572087A4 (de) | 2006-11-02 |
| PT1572087E (pt) | 2008-07-11 |
| US20080160012A1 (en) | 2008-07-03 |
| KR20050002848A (ko) | 2005-01-10 |
| DK1572087T3 (da) | 2008-08-25 |
| ES2305481T3 (es) | 2008-11-01 |
| US20040096392A1 (en) | 2004-05-20 |
| CA2478683C (en) | 2016-01-26 |
| JP5192537B2 (ja) | 2013-05-08 |
| US8257708B2 (en) | 2012-09-04 |
| US20110038864A1 (en) | 2011-02-17 |
| EP1572087A2 (de) | 2005-09-14 |
| AU2003252830B2 (en) | 2008-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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