CY1114885T1 - Βελτιωμενη σταθεροτητα διαλυτοποιησης για δισκια ανθρακικου ασβεστιου - Google Patents
Βελτιωμενη σταθεροτητα διαλυτοποιησης για δισκια ανθρακικου ασβεστιουInfo
- Publication number
- CY1114885T1 CY1114885T1 CY20131101107T CY131101107T CY1114885T1 CY 1114885 T1 CY1114885 T1 CY 1114885T1 CY 20131101107 T CY20131101107 T CY 20131101107T CY 131101107 T CY131101107 T CY 131101107T CY 1114885 T1 CY1114885 T1 CY 1114885T1
- Authority
- CY
- Cyprus
- Prior art keywords
- composition
- mannitol
- solution stability
- improved solution
- stearate
- Prior art date
Links
- JETSKDPKURDVNI-UHFFFAOYSA-N [C].[Ca] Chemical compound [C].[Ca] JETSKDPKURDVNI-UHFFFAOYSA-N 0.000 title 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 3
- 229930195725 Mannitol Natural products 0.000 abstract 3
- 239000000594 mannitol Substances 0.000 abstract 3
- 235000010355 mannitol Nutrition 0.000 abstract 3
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 235000021355 Stearic acid Nutrition 0.000 abstract 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 abstract 1
- 239000008116 calcium stearate Substances 0.000 abstract 1
- 235000013539 calcium stearate Nutrition 0.000 abstract 1
- 239000000905 isomalt Substances 0.000 abstract 1
- 235000010439 isomalt Nutrition 0.000 abstract 1
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000002594 sorbent Substances 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 239000008117 stearic acid Substances 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08169264 | 2008-11-17 | ||
| EP09763835.7A EP2358374B1 (en) | 2008-11-17 | 2009-11-17 | Improved dissolution stability of calcium carbonate tablets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1114885T1 true CY1114885T1 (el) | 2016-12-14 |
Family
ID=40456895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20131101107T CY1114885T1 (el) | 2008-11-17 | 2013-12-09 | Βελτιωμενη σταθεροτητα διαλυτοποιησης για δισκια ανθρακικου ασβεστιου |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9101565B2 (enExample) |
| EP (1) | EP2358374B1 (enExample) |
| JP (1) | JP5523467B2 (enExample) |
| KR (1) | KR101807318B1 (enExample) |
| CN (1) | CN102215847B (enExample) |
| AU (1) | AU2009315917B2 (enExample) |
| BR (1) | BRPI0921599B8 (enExample) |
| CA (1) | CA2742449C (enExample) |
| CY (1) | CY1114885T1 (enExample) |
| DK (1) | DK2358374T3 (enExample) |
| EA (1) | EA021707B1 (enExample) |
| ES (1) | ES2437851T3 (enExample) |
| HR (1) | HRP20131084T1 (enExample) |
| IL (1) | IL212442A (enExample) |
| MX (1) | MX2011004744A (enExample) |
| NZ (1) | NZ592528A (enExample) |
| PL (1) | PL2358374T3 (enExample) |
| PT (1) | PT2358374E (enExample) |
| SI (1) | SI2358374T1 (enExample) |
| SM (1) | SMT201400014B (enExample) |
| WO (1) | WO2010054845A1 (enExample) |
| ZA (1) | ZA201103421B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2358374B1 (en) | 2008-11-17 | 2013-09-18 | Takeda Nycomed AS | Improved dissolution stability of calcium carbonate tablets |
| EP2575755A2 (en) | 2010-06-01 | 2013-04-10 | Cargill, Incorporated | Orodispersible tablets of erythritol and isomalt |
| EP3260114A1 (en) * | 2016-06-21 | 2017-12-27 | Omya International AG | Method for the production of a dosage form |
| CN107281216B (zh) * | 2017-06-16 | 2020-05-05 | 北京济美堂医药研究有限公司 | 含钙化合物的药物制剂 |
| CN110575440A (zh) * | 2018-06-08 | 2019-12-17 | 北京新领先医药科技发展有限公司 | 一种碳酸钙药物组合物的制备方法 |
| HUE068040T2 (hu) | 2019-07-05 | 2024-12-28 | Tecnimede Sociedade Tecnico Medicinal Sa | Préselt macitentán készítmények, eljárások és ezek felhasználása |
| JP7774867B2 (ja) * | 2021-10-04 | 2025-11-25 | 備前化成株式会社 | 食品錠剤の製造方法 |
| WO2024028300A1 (en) * | 2022-08-04 | 2024-02-08 | Symrise Ag | Process for the preparation of a powder or of a pastille |
| KR102675165B1 (ko) * | 2023-02-20 | 2024-06-13 | 동아제약 주식회사 | 필름 코팅용 조성물 및 이를 포함하는 필름 코팅액 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115553A (en) * | 1973-12-10 | 1978-09-19 | Armour Pharmaceutical Company | Antacid tablets |
| US5204115A (en) | 1990-12-12 | 1993-04-20 | Suomen Xyrofin Oy | Directly compressible xylitol and method |
| JP2995226B2 (ja) | 1992-03-03 | 1999-12-27 | 日本ワイスレダリー株式会社 | カルシウム含有チユアブル錠 |
| US5405623A (en) | 1993-09-22 | 1995-04-11 | Wm. Wrigley Jr. Company | Chewing gum compositions and methods for manufacturing same |
| DE4427137B4 (de) | 1993-10-07 | 2007-08-23 | Degussa Gmbh | Fällungskieselsäure |
| US6716454B2 (en) * | 1994-09-23 | 2004-04-06 | Laboratorie Innothera, Société Anonyme | Therapeutic combination of vitamin and calcium in unitary galenic tablet form, a method of obtaining it, and the use thereof |
| FR2724844B1 (fr) | 1994-09-23 | 1997-01-24 | Innothera Lab Sa | Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation |
| US5846506A (en) | 1994-10-07 | 1998-12-08 | Degussa Aktiengesellschaft | Precipitated silicas |
| DE19617487A1 (de) | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Geschmacksverbesserung von Arzneimittelwirkstoffen |
| DE69739967D1 (de) | 1996-06-14 | 2010-09-30 | Kyowa Hakko Kirin Co Ltd | Eine im Mund schnell zerfallende Tablette |
| FR2762217B1 (fr) | 1997-04-16 | 2000-09-29 | Besins Iscovesco Lab | Preparation solide vitamino-calcique, son procede d'obtention et son utilisation |
| ITFI970184A1 (it) | 1997-07-30 | 1999-01-30 | Menarini Farma Ind | Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico |
| GB9825033D0 (en) | 1998-11-13 | 1999-01-13 | Nycomed Pharma As | Process |
| JP2001316249A (ja) | 2000-05-11 | 2001-11-13 | Lion Corp | 錠剤型医薬組成物 |
| EP1369131A1 (en) | 2001-03-06 | 2003-12-10 | Kyowa Hakko Kogyo Co., Ltd. | Utilization of spray-dried powder containing sugar alcohol |
| EP1369109A1 (en) | 2001-03-06 | 2003-12-10 | Kyowa Hakko Kogyo Co., Ltd. | Preparations quickly disintegrating in oral cavity |
| IL159584A0 (en) * | 2001-07-16 | 2004-06-01 | Astrazeneca Ab | Pharmaceutical formulation comprising a proton pump inhibitor and antacids |
| ES2192136B1 (es) | 2002-01-04 | 2005-03-16 | Italfarmaco, S.A. | Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis. |
| DE20216314U1 (de) | 2002-10-22 | 2003-12-04 | Dhw Deutsche Hydrierwerke Gmbh Rodleben | Sprühgetrockneter Xylitol und aus diesem hergestellte Komprimate |
| MXPA06013608A (es) * | 2004-05-24 | 2007-04-26 | Nycomed Pharma As | Particulado que comprende un compuesto que contiene calcio y un alcohol de azucar. |
| JP4996458B2 (ja) | 2004-06-01 | 2012-08-08 | ニコメド ファーマ エイエス | 活性物質としてカルシウム含有化合物を含み、咀嚼し、舐め、飲み込むことのできる錠剤 |
| JP5224820B2 (ja) * | 2005-02-03 | 2013-07-03 | ニコメド ファーマ エイエス | カルシウム含有化合物を含む組成物の溶融造粒 |
| UA95093C2 (uk) * | 2005-12-07 | 2011-07-11 | Нікомед Фарма Ас | Спосіб одержання кальцієвмісної сполуки |
| AU2006322452B2 (en) * | 2005-12-07 | 2012-07-12 | Takeda Nycomed As | Pre-compacted calcium-containing compositions |
| EP2104993A2 (en) | 2007-01-16 | 2009-09-30 | Koninklijke Philips Electronics N.V. | Device discovery for mixed types of directional terminals |
| EP2358374B1 (en) | 2008-11-17 | 2013-09-18 | Takeda Nycomed AS | Improved dissolution stability of calcium carbonate tablets |
-
2009
- 2009-11-17 EP EP09763835.7A patent/EP2358374B1/en active Active
- 2009-11-17 BR BRPI0921599A patent/BRPI0921599B8/pt active IP Right Grant
- 2009-11-17 ES ES09763835.7T patent/ES2437851T3/es active Active
- 2009-11-17 NZ NZ592528A patent/NZ592528A/xx unknown
- 2009-11-17 US US13/129,664 patent/US9101565B2/en active Active
- 2009-11-17 DK DK09763835.7T patent/DK2358374T3/da active
- 2009-11-17 PT PT97638357T patent/PT2358374E/pt unknown
- 2009-11-17 JP JP2011535926A patent/JP5523467B2/ja active Active
- 2009-11-17 SI SI200930789T patent/SI2358374T1/sl unknown
- 2009-11-17 HR HRP20131084AT patent/HRP20131084T1/hr unknown
- 2009-11-17 PL PL09763835T patent/PL2358374T3/pl unknown
- 2009-11-17 CN CN200980145721.9A patent/CN102215847B/zh active Active
- 2009-11-17 CA CA2742449A patent/CA2742449C/en active Active
- 2009-11-17 EA EA201170695A patent/EA021707B1/ru unknown
- 2009-11-17 AU AU2009315917A patent/AU2009315917B2/en active Active
- 2009-11-17 WO PCT/EP2009/008157 patent/WO2010054845A1/en not_active Ceased
- 2009-11-17 KR KR1020117013113A patent/KR101807318B1/ko active Active
- 2009-11-17 MX MX2011004744A patent/MX2011004744A/es active IP Right Grant
-
2011
- 2011-04-17 IL IL212442A patent/IL212442A/en active IP Right Grant
- 2011-05-10 ZA ZA2011/03421A patent/ZA201103421B/en unknown
-
2013
- 2013-12-09 CY CY20131101107T patent/CY1114885T1/el unknown
-
2014
- 2014-01-29 SM SM201400014T patent/SMT201400014B/xx unknown
-
2015
- 2015-07-24 US US14/808,420 patent/US9999634B2/en active Active
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