BRPI0921599B8 - método para a preparação de um comprimido, e, comprimido de carbonato de cálcio - Google Patents

método para a preparação de um comprimido, e, comprimido de carbonato de cálcio

Info

Publication number
BRPI0921599B8
BRPI0921599B8 BRPI0921599A BRPI0921599A BRPI0921599B8 BR PI0921599 B8 BRPI0921599 B8 BR PI0921599B8 BR PI0921599 A BRPI0921599 A BR PI0921599A BR PI0921599 A BRPI0921599 A BR PI0921599A BR PI0921599 B8 BRPI0921599 B8 BR PI0921599B8
Authority
BR
Brazil
Prior art keywords
tablet
calcium carbonate
preparing
combinations
punches
Prior art date
Application number
BRPI0921599A
Other languages
English (en)
Inventor
Ravn Aage Henrik
Mohr Olsen Peder
Egon Bertelsen Poul
Thisted Thomas
Original Assignee
Nycomed Pharma As
Takeda As
Takeda Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Pharma As, Takeda As, Takeda Nycomed As filed Critical Nycomed Pharma As
Publication of BRPI0921599A2 publication Critical patent/BRPI0921599A2/pt
Publication of BRPI0921599B1 publication Critical patent/BRPI0921599B1/pt
Publication of BRPI0921599B8 publication Critical patent/BRPI0921599B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats

Abstract

método para a preparação de um comprimido, e, comprimido de carbonato de cálcio. a presente invenção refere-se a um método para a preparação de um comprimido contendo pelo menos 50% p/p de carbonato de cálcio, o método compreendendo :i) prover uma composição particulada contendo a) carbonato de cálcio, b) um álcool de açúcar aglutinante selecionado entre sorbitol ou isomalte, ou combinações dos mesmos, c) um álcool de açúcar não aglutinante selecionado entre manitol, maltiol ou xilitol, ou combinações dos mesmos, e ii) comprimir a referida composição usando uma máquina de compressão equipada com pelo menos um par de punções e matrizes, na qual o par de punções e matrizes antes do enchimento da matriz com a referida composição particulada é pulverizada com uma composição contendo lubrificante selecionado entre estearato de magnésio, estearato de cálcio ou ácido esteárico ou combinações dos mesmos.
BRPI0921599A 2008-11-17 2009-11-17 método para a preparação de um comprimido, e, comprimido de carbonato de cálcio BRPI0921599B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08169264.2 2008-11-17
EP08169264 2008-11-17
PCT/EP2009/008157 WO2010054845A1 (en) 2008-11-17 2009-11-17 Improved dissolution stability of calcium carbonate tablets

Publications (3)

Publication Number Publication Date
BRPI0921599A2 BRPI0921599A2 (pt) 2016-02-10
BRPI0921599B1 BRPI0921599B1 (pt) 2020-08-18
BRPI0921599B8 true BRPI0921599B8 (pt) 2021-05-25

Family

ID=40456895

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0921599A BRPI0921599B8 (pt) 2008-11-17 2009-11-17 método para a preparação de um comprimido, e, comprimido de carbonato de cálcio

Country Status (23)

Country Link
US (2) US9101565B2 (pt)
EP (1) EP2358374B1 (pt)
JP (1) JP5523467B2 (pt)
KR (1) KR101807318B1 (pt)
CN (1) CN102215847B (pt)
AU (1) AU2009315917B2 (pt)
BR (1) BRPI0921599B8 (pt)
CA (1) CA2742449C (pt)
CY (1) CY1114885T1 (pt)
DK (1) DK2358374T3 (pt)
EA (1) EA021707B1 (pt)
ES (1) ES2437851T3 (pt)
HK (1) HK1162354A1 (pt)
HR (1) HRP20131084T1 (pt)
IL (1) IL212442A (pt)
MX (1) MX2011004744A (pt)
NZ (1) NZ592528A (pt)
PL (1) PL2358374T3 (pt)
PT (1) PT2358374E (pt)
SI (1) SI2358374T1 (pt)
SM (1) SMT201400014B (pt)
WO (1) WO2010054845A1 (pt)
ZA (1) ZA201103421B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2358374T3 (pl) 2008-11-17 2014-03-31 Takeda As Ulepszona stabilność rozpuszczania tabletek węglanu wapnia
CA2800266A1 (en) 2010-06-01 2011-12-08 Cargill, Incorporated Orodispersible tablets of erythritol and isomalt
EP3260114A1 (en) * 2016-06-21 2017-12-27 Omya International AG Method for the production of a dosage form
CN107281216B (zh) * 2017-06-16 2020-05-05 北京济美堂医药研究有限公司 含钙化合物的药物制剂
CN110575440A (zh) * 2018-06-08 2019-12-17 北京新领先医药科技发展有限公司 一种碳酸钙药物组合物的制备方法
WO2021005478A1 (en) 2019-07-05 2021-01-14 TECNIMEDE - Sociedade Técnico-medicinal, SA Compressed macitentan compositions, methods and uses thereof
JP2023054786A (ja) * 2021-10-04 2023-04-14 備前化成株式会社 食品錠剤の製造方法
WO2024028300A1 (en) * 2022-08-04 2024-02-08 Symrise Ag Process for the preparation of a powder or of a pastille

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JP2995226B2 (ja) 1992-03-03 1999-12-27 日本ワイスレダリー株式会社 カルシウム含有チユアブル錠
US5405623A (en) 1993-09-22 1995-04-11 Wm. Wrigley Jr. Company Chewing gum compositions and methods for manufacturing same
DE4427137B4 (de) 1993-10-07 2007-08-23 Degussa Gmbh Fällungskieselsäure
FR2724844B1 (fr) 1994-09-23 1997-01-24 Innothera Lab Sa Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation
US6716454B2 (en) * 1994-09-23 2004-04-06 Laboratorie Innothera, Société Anonyme Therapeutic combination of vitamin and calcium in unitary galenic tablet form, a method of obtaining it, and the use thereof
US5846506A (en) 1994-10-07 1998-12-08 Degussa Aktiengesellschaft Precipitated silicas
DE19617487A1 (de) 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
ATE297191T1 (de) 1996-06-14 2005-06-15 Kyowa Hakko Kogyo Kk Im munde schnellzerfallende tablette
FR2762217B1 (fr) 1997-04-16 2000-09-29 Besins Iscovesco Lab Preparation solide vitamino-calcique, son procede d'obtention et son utilisation
ITFI970184A1 (it) 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
GB9825033D0 (en) 1998-11-13 1999-01-13 Nycomed Pharma As Process
JP2001316249A (ja) 2000-05-11 2001-11-13 Lion Corp 錠剤型医薬組成物
US20040121006A1 (en) 2001-03-06 2004-06-24 Shoichi Narita Utilization of spray-dried powder containing sugar alcohol
WO2002069934A1 (fr) 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Préparations se délitant rapidement dans la bouche
AU2002316020B2 (en) * 2001-07-16 2007-03-15 Astrazeneca Ab Pharmaceutical formulation comprising a proton pump inhibitor and antacids
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TWI356712B (en) * 2004-05-24 2012-01-21 Nycomed Pharma As Agglomeration of a calcium-containing compound by
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EP1845949B1 (en) * 2005-02-03 2008-05-21 Nycomed Pharma AS Melt granulation of a composition containing a calcium-containing compound
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
WO2007065440A1 (en) * 2005-12-07 2007-06-14 Nycomed Pharma As Pre-compacted calcium-containing compositions
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PL2358374T3 (pl) 2008-11-17 2014-03-31 Takeda As Ulepszona stabilność rozpuszczania tabletek węglanu wapnia

Also Published As

Publication number Publication date
AU2009315917B2 (en) 2014-11-20
EP2358374A1 (en) 2011-08-24
KR20110086592A (ko) 2011-07-28
EA021707B1 (ru) 2015-08-31
BRPI0921599B1 (pt) 2020-08-18
SI2358374T1 (sl) 2014-01-31
US9999634B2 (en) 2018-06-19
US20160022732A1 (en) 2016-01-28
HK1162354A1 (en) 2012-08-31
EA201170695A1 (ru) 2011-12-30
BRPI0921599A2 (pt) 2016-02-10
IL212442A (en) 2015-10-29
CN102215847A (zh) 2011-10-12
HRP20131084T1 (hr) 2013-12-20
MX2011004744A (es) 2011-05-30
PT2358374E (pt) 2013-12-09
EP2358374B1 (en) 2013-09-18
US9101565B2 (en) 2015-08-11
CA2742449A1 (en) 2010-05-20
CN102215847B (zh) 2014-07-16
WO2010054845A1 (en) 2010-05-20
CA2742449C (en) 2018-04-24
PL2358374T3 (pl) 2014-03-31
IL212442A0 (en) 2011-06-30
ZA201103421B (en) 2012-10-31
DK2358374T3 (da) 2013-11-11
JP2012508706A (ja) 2012-04-12
CY1114885T1 (el) 2016-12-14
NZ592528A (en) 2013-05-31
AU2009315917A1 (en) 2010-05-20
SMT201400014B (it) 2014-03-07
US20110287098A1 (en) 2011-11-24
KR101807318B1 (ko) 2018-01-10
ES2437851T3 (es) 2014-01-14
JP5523467B2 (ja) 2014-06-18

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: TAKEDA NYCOMED AS (NO)

B25D Requested change of name of applicant approved

Owner name: TAKEDA AS (NO)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/08/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/11/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF