CY1110749T1 - Νεα παραγωγα ξανθινης, παραγωγη αυτων και χρηση τους ως φαρμακων - Google Patents

Νεα παραγωγα ξανθινης, παραγωγη αυτων και χρηση τους ως φαρμακων

Info

Publication number
CY1110749T1
CY1110749T1 CY20101100774T CY101100774T CY1110749T1 CY 1110749 T1 CY1110749 T1 CY 1110749T1 CY 20101100774 T CY20101100774 T CY 20101100774T CY 101100774 T CY101100774 T CY 101100774T CY 1110749 T1 CY1110749 T1 CY 1110749T1
Authority
CY
Cyprus
Prior art keywords
xanthinis
medicines
production
new products
properties
Prior art date
Application number
CY20101100774T
Other languages
English (en)
Inventor
Frank Himmelsbach
Elke Langkopf
Matthias Eckhardt
Roland Maier
Michael Mark
Mohammad Tadayyon
Ralf R H Lotz
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg
Publication of CY1110749T1 publication Critical patent/CY1110749T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Abstract

Η παρούσα εφεύρεση αφορά υποκατεστημένες ξανθίνες του γενικού τύπου (I), στον οποίο τα R1 έως R4 ορίζονται όπως στην αξίωση 1, τα ταυτομερή τους, τα στερεοϊσομερή τους, τα μείγματα τους, τα προφάρμακά τους και τα άλατα τους, τα οποία έχουν πολύτιμες φαρμακολογικές ιδιότητες, ιδιαιτέρως ανασταλτική δράση στη δραστικότητα του ενζύμου διπεπτιδυλ-πεπτιδάση-IV (DPP-IV).
CY20101100774T 2002-11-08 2010-08-20 Νεα παραγωγα ξανθινης, παραγωγη αυτων και χρηση τους ως φαρμακων CY1110749T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10251927A DE10251927A1 (de) 2002-11-08 2002-11-08 Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
EP03788995A EP1562946B1 (de) 2002-11-08 2003-11-03 Neue xanthinderivate, deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
CY1110749T1 true CY1110749T1 (el) 2015-06-10

Family

ID=32115363

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100774T CY1110749T1 (el) 2002-11-08 2010-08-20 Νεα παραγωγα ξανθινης, παραγωγη αυτων και χρηση τους ως φαρμακων

Country Status (16)

Country Link
EP (2) EP2228375A1 (el)
JP (2) JP4832758B2 (el)
AR (1) AR043060A1 (el)
AT (1) ATE469152T1 (el)
AU (1) AU2003293649A1 (el)
CA (1) CA2505389C (el)
CY (1) CY1110749T1 (el)
DE (2) DE10251927A1 (el)
DK (1) DK1562946T5 (el)
ES (1) ES2346432T3 (el)
PE (1) PE20040829A1 (el)
PT (1) PT1562946E (el)
SI (1) SI1562946T1 (el)
TW (1) TW200512210A (el)
UY (1) UY28069A1 (el)
WO (1) WO2004041820A1 (el)

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DK1368349T3 (da) * 2001-02-24 2007-05-21 Boehringer Ingelheim Pharma Xanthinderivater, deres fremstilling og deres anvendelse som lægemidler
WO2003024965A2 (en) * 2001-09-19 2003-03-27 Novo Nordisk A/S Heterocyclic compounds that are inhibitors of the enzyme dpp-iv
PL403104A1 (pl) * 2002-08-21 2013-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sposób otrzymywania kompozycji farmaceutycznej zawierajacej pochodne 8-[3-aminopiperydyn-1-ylo]ksantyny
DE10251927A1 (de) * 2002-11-08 2004-05-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel

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ATE469152T1 (de) 2010-06-15
CA2505389C (en) 2012-01-10
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UY28069A1 (es) 2004-06-30
WO2004041820A1 (de) 2004-05-21
DE10251927A1 (de) 2004-05-19
EP1562946A1 (de) 2005-08-17
EP1562946B1 (de) 2010-05-26
TW200512210A (en) 2005-04-01
ES2346432T3 (es) 2010-10-15
JP4832758B2 (ja) 2011-12-07
DK1562946T3 (da) 2010-09-20
AU2003293649A1 (en) 2004-06-07
PE20040829A1 (es) 2005-01-14
AR043060A1 (es) 2005-07-13
CA2505389A1 (en) 2004-05-21
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SI1562946T1 (sl) 2010-11-30
EP2228375A1 (de) 2010-09-15

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