DK1513800T3 - Benzoylureido-kanelsyrederivater, fremgangsmåde til deres anvendelse - Google Patents

Benzoylureido-kanelsyrederivater, fremgangsmåde til deres anvendelse

Info

Publication number
DK1513800T3
DK1513800T3 DK03732438T DK03732438T DK1513800T3 DK 1513800 T3 DK1513800 T3 DK 1513800T3 DK 03732438 T DK03732438 T DK 03732438T DK 03732438 T DK03732438 T DK 03732438T DK 1513800 T3 DK1513800 T3 DK 1513800T3
Authority
DK
Denmark
Prior art keywords
benzoylureido
acid derivatives
cinnamic acid
derivatives
benzoylureidocinnamate
Prior art date
Application number
DK03732438T
Other languages
English (en)
Inventor
Karl-Ulrich Wendt
Karl Schoenafinger
Elisabeth Defossa
Dieter Kadereit
Roedern Erich Von
Hans-Joerg Burger
Andreas Herling
Thomas Klabunde
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1513800T3 publication Critical patent/DK1513800T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48Y being a hydrogen or a carbon atom
    • C07C275/54Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03732438T 2002-06-07 2003-05-22 Benzoylureido-kanelsyrederivater, fremgangsmåde til deres anvendelse DK1513800T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10225635A DE10225635C1 (de) 2002-06-07 2002-06-07 N-Benzoylureido-Zimtsäurederivate, Verfahren zu deren Herstellung und deren Verwendung
PCT/EP2003/005355 WO2003104188A1 (de) 2002-06-07 2003-05-22 N-benzoylureido-zimtsäurederivate, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
DK1513800T3 true DK1513800T3 (da) 2007-03-26

Family

ID=29594346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03732438T DK1513800T3 (da) 2002-06-07 2003-05-22 Benzoylureido-kanelsyrederivater, fremgangsmåde til deres anvendelse

Country Status (26)

Country Link
EP (1) EP1513800B1 (da)
JP (1) JP4398859B2 (da)
KR (1) KR20050004295A (da)
CN (1) CN1659137A (da)
AT (1) ATE345326T1 (da)
AU (1) AU2003238373A1 (da)
BR (1) BR0311646A (da)
CA (1) CA2488760A1 (da)
CY (1) CY1106003T1 (da)
DE (2) DE10225635C1 (da)
DK (1) DK1513800T3 (da)
ES (1) ES2277082T3 (da)
HR (1) HRPK20041161B3 (da)
IL (1) IL165558A0 (da)
IN (1) IN2004CH02747A (da)
MA (1) MA27232A1 (da)
MX (1) MXPA04011984A (da)
NO (1) NO20050087L (da)
NZ (1) NZ537004A (da)
PL (1) PL372117A1 (da)
PT (1) PT1513800E (da)
RU (1) RU2004139122A (da)
SI (1) SI1513800T1 (da)
TW (1) TW200404763A (da)
WO (1) WO2003104188A1 (da)
ZA (1) ZA200408887B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10302452B4 (de) * 2003-01-23 2005-02-24 Aventis Pharma Deutschland Gmbh Carbonylamino-substituierte Acyl-phenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
US7179941B2 (en) 2003-01-23 2007-02-20 Sanofi-Aventis Deutschland Gmbh Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
DE10306502B4 (de) * 2003-02-17 2005-03-17 Aventis Pharma Deutschland Gmbh Substituierte 3-(Benzoylureido)-thiophenderivate und sie enthaltende Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308351A1 (de) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10335092B3 (de) 2003-08-01 2005-02-03 Aventis Pharma Deutschland Gmbh Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
DE602004004631D1 (de) 2004-04-01 2007-03-22 Sanofi Aventis Deutschland Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
WO2006055435A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7214704B2 (en) 2004-11-15 2007-05-08 Bristol-Myers Squibb Company 2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006055462A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
TW200718691A (en) 2005-06-10 2007-05-16 Sigma Tau Ind Farmaceuti Cinnamic and phenylpropiolic acid derivatives useful as anti-tumour agents
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL141381B (nl) * 1963-09-25 1974-03-15 Hoechst Ag Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid.
IE860511L (en) * 1985-03-01 1986-09-01 Alfa Farmaceutici Spa "Benzoyl urea derivatives having anti-tumor activity"
ZA867420B (en) * 1985-09-30 1987-05-27 Union Carbide Corp Pesticidal 1-(4-aryloxyphenyl)-3-benzoyl urea compounds and process for preparation
DE4037112A1 (de) * 1990-11-22 1992-05-27 Thomae Gmbh Dr K Neue pyridylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
MX9709874A (es) * 1995-06-06 1998-03-31 Pfizer N-(INDOL-2-CARBONIL) beta-ALANILAMIDAS SUSTITUIDAS Y DERIVADOS COMO INHIBIDORES DE GLUCOGENO FOSFORILASA, USO DE LOS MISMOS Y COMPOSICIONES QUE LOS CONTIENEN.
GT200100039A (es) * 2000-03-16 2001-12-31 Pfizer Inhibidor de la glucogeno fosforilasa.
NZ523034A (en) * 2000-06-09 2004-07-30 Aventis Pharma Gmbh Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
GB0021831D0 (en) * 2000-09-06 2000-10-18 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
EP1513800A1 (de) 2005-03-16
IN2004CH02747A (da) 2006-02-10
ES2277082T3 (es) 2007-07-01
TW200404763A (en) 2004-04-01
PL372117A1 (en) 2005-07-11
WO2003104188A1 (de) 2003-12-18
ATE345326T1 (de) 2006-12-15
NO20050087L (no) 2005-01-06
MXPA04011984A (es) 2005-03-07
ZA200408887B (en) 2005-11-23
DE10225635C1 (de) 2003-12-24
NZ537004A (en) 2006-06-30
CN1659137A (zh) 2005-08-24
EP1513800B1 (de) 2006-11-15
DE50305693D1 (de) 2006-12-28
JP4398859B2 (ja) 2010-01-13
JP2005529164A (ja) 2005-09-29
SI1513800T1 (sl) 2007-04-30
AU2003238373A1 (en) 2003-12-22
RU2004139122A (ru) 2005-06-10
BR0311646A (pt) 2005-03-15
IL165558A0 (en) 2006-01-15
MA27232A1 (fr) 2005-02-01
HRP20041161A2 (en) 2005-04-30
HRPK20041161B3 (en) 2006-09-30
PT1513800E (pt) 2007-02-28
CA2488760A1 (en) 2003-12-18
KR20050004295A (ko) 2005-01-12
CY1106003T1 (el) 2011-04-06

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