CY1110216T1 - Παραγωγα αρυλαλκυλκαρβαμικων, η παρασκευη τους και η εφαρμογη τους στη θεραπευτικη αγωγη - Google Patents

Παραγωγα αρυλαλκυλκαρβαμικων, η παρασκευη τους και η εφαρμογη τους στη θεραπευτικη αγωγη

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Publication number
CY1110216T1
CY1110216T1 CY20101100676T CY101100676T CY1110216T1 CY 1110216 T1 CY1110216 T1 CY 1110216T1 CY 20101100676 T CY20101100676 T CY 20101100676T CY 101100676 T CY101100676 T CY 101100676T CY 1110216 T1 CY1110216 T1 CY 1110216T1
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CY
Cyprus
Prior art keywords
cycloalkyl
alkyl
group
alkylene
optionally substituted
Prior art date
Application number
CY20101100676T
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English (en)
Inventor
Ahmed Abouabdellah
Garcia Antonio Almario
Christian Hoornaert
Antoine Ravet
Original Assignee
Sanofi-Aventis
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Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of CY1110216T1 publication Critical patent/CY1110216T1/el

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    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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Abstract

Ένωση η οποία αντιστοιχεί στον γενικό χημικό τύπο (I) στον οποίο το n αντιστοιχεί σε έναν ακέραιο αριθμό ο οποίος κυμαίνεται από 1 έως 7∙ το Α επιλέγεται μεταξύ μιας ή περισσοτέρων ομάδων Χ, Υ και/ή Ζ ∙ το Χ αντιπροσωπεύει μια ομάδα C1-2-αλκυλεν ενδεχομένως υποκατεστημένη από μια ή περισσότερες ομάδες C1-2-αλκυλ, C3-7-κυκλοαλκυλ ή C3-7-κυκλοαλκυλ-C1-6-αλκυλεν∙ το Υ αντιπροσωπεύει μια ομάδα C2-αλκενυλεν ενδεχομένως υποκατεστημένη από μια ή περισσότερες ομάδες C1-12 αλκυλ, C3-7-κυκλοαλκυλ ή C 3-7-κυκλοαλκυλ- C 1-6-αλκυλεν∙ το Ζ αντιπροσωπεύει μια ομάδα C3-7-κυκλοαλκυλ, του χημικού τύπου, το m αντιπροσωπεύει έναν ακέραιο αριθμό ο οποίος κυμαίνεται από 1 έως 5∙ το p και το q αντιπροσωπεύουν ακέραιους αριθμούς και ορίζονται ως p+q ένας αριθμός ο οποίος κυμαίνεται μεταξύ 1 έως 5∙ το R1 αντιπροσωπεύει ένα άτομο υδρογόνου, αλογόνου ή μια ομάδα υδροξυλ, κυανό, νίτρο, C1-4-αλκυλ, C1-4-αλκοξυ, C1-4-θειοαλκυλ, C1-4-φθοροαλκυλ, C1-4-φθοροαλκοξυ, C1-4-φθοροθειοαλκυλ . το R2 αντιπροσωπεύει ένα άτομο υδρογόνου, αλογόνου, ή μια ομάδα κυανό, νίτρο, υδροξυλ, C1-4-αλκυλ, C1-4-αλκοξυ, C1-4-θειοαλκυλ, C1-4-φθοροαλκυλ, C1-4-φθοροαλκοξυ, C1-4-φθοροθειοαλκυλ, ή μια ομάδα τύπου αρυλ ή ετεροαρυλ ενδεχομένως υποκατεστημένη από έναν ή περισσότερους υποκατάστατες . το R3 αντιπροσωπεύει μια ομάδα του γενικού χημικού τύπου CHR4CONHR5 στον οποίο το R4 αντιπροσωπεύει ένα άτομο υδρογόνου ή μια ομάδα C1-3-αλκυλ και το R5 αντιπροσωπεύει ένα άτομο υδρογόνου ή μια ομάδα C1-3-αλκυλ, C3-5-κυκλοαλκυλ, C3-7-κυκλοαλκυλ-C1-6-αλκυλεν∙ σε κατάσταση βάσης, άλατος προσθήκης σε ένα οξύ, υδρίτη ή διαλύτη. Εφαρμογή στη θεραπευτική αγωγή.
CY20101100676T 2003-01-23 2010-07-20 Παραγωγα αρυλαλκυλκαρβαμικων, η παρασκευη τους και η εφαρμογη τους στη θεραπευτικη αγωγη CY1110216T1 (el)

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FR0300704A FR2850377B1 (fr) 2003-01-23 2003-01-23 Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
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PT1590321E (pt) 2010-07-06
FR2850377B1 (fr) 2009-02-20
BRPI0406901A (pt) 2005-12-13
EP1590321B1 (fr) 2010-04-28
TNSN05172A1 (fr) 2007-05-14
CN101058564A (zh) 2007-10-24
NO20053593L (no) 2005-10-21
NO20053593D0 (no) 2005-07-22
IS7916A (is) 2005-06-27
EA200500979A1 (ru) 2006-02-24
CN1741990A (zh) 2006-03-01
MXPA05007848A (es) 2005-10-18
IL169444A0 (en) 2007-07-04
SI1590321T1 (sl) 2010-08-31
DE602004026826D1 (de) 2010-06-10
CA2511941A1 (en) 2004-08-12
DK1590321T3 (da) 2010-08-09
JP2006517218A (ja) 2006-07-20
EA008801B1 (ru) 2007-08-31
RS20050562A (en) 2007-12-31
TW200503993A (en) 2005-02-01
JP4617292B2 (ja) 2011-01-19
AU2004207657B2 (en) 2010-09-16
HRP20050631A2 (en) 2005-08-31
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CN101058564B (zh) 2010-05-26
WO2004067498A3 (fr) 2004-11-04
US20060014830A1 (en) 2006-01-19
WO2004067498A2 (fr) 2004-08-12
CN100506788C (zh) 2009-07-01
MA27609A1 (fr) 2005-11-01
UA86013C2 (ru) 2009-03-25
TWI330628B (en) 2010-09-21
EP1590321A2 (fr) 2005-11-02
KR20050104352A (ko) 2005-11-02
IL169444A (en) 2011-06-30
ZA200505351B (en) 2006-09-27
NZ541148A (en) 2009-01-31
HK1085193A1 (en) 2006-08-18
FR2850377A1 (fr) 2004-07-30
ATE465990T1 (de) 2010-05-15
MEP21308A (en) 2010-06-10
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