CY1109168T1 - Συνθεση νατριουχου φονταπαρινοξης υψηλης καθαροτητας - Google Patents

Συνθεση νατριουχου φονταπαρινοξης υψηλης καθαροτητας

Info

Publication number
CY1109168T1
CY1109168T1 CY20091100645T CY091100645T CY1109168T1 CY 1109168 T1 CY1109168 T1 CY 1109168T1 CY 20091100645 T CY20091100645 T CY 20091100645T CY 091100645 T CY091100645 T CY 091100645T CY 1109168 T1 CY1109168 T1 CY 1109168T1
Authority
CY
Cyprus
Prior art keywords
composition
sodium
fontaparinox
clear
pharmaceutical compositions
Prior art date
Application number
CY20091100645T
Other languages
English (en)
Inventor
Jean-François Branellec
Christian Morello
Pierre Potier
Patrick Trouilleux
Petrus Marcus Fm Bastiaansen
Henricus Cornelis Jozephus Claassen
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of CY1109168T1 publication Critical patent/CY1109168T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η παρούσα εφεύρεση αφορά μία σύνθεση νατριούχου φονταπαρινόξης υψηλής καθαρότητας, όπου στον καθαρισμό συμμετέχει ενεργός άνθρακας, μία μέθοδο παρασκευής αυτής της συνθέσεως για χρήση σε φαρμακευτικές συνθέσεις, καθώς και τις φαρμακευτικές συνθέσεις που την περιέχουν ως δραστικό παράγοντα.
CY20091100645T 2003-02-27 2009-06-18 Συνθεση νατριουχου φονταπαρινοξης υψηλης καθαροτητας CY1109168T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37526803A 2003-02-27 2003-02-27
EP04710418A EP1625135B1 (fr) 2003-02-27 2004-02-12 Composition de fondaparinux sodique de haute purete

Publications (1)

Publication Number Publication Date
CY1109168T1 true CY1109168T1 (el) 2014-07-02

Family

ID=32961215

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100645T CY1109168T1 (el) 2003-02-27 2009-06-18 Συνθεση νατριουχου φονταπαρινοξης υψηλης καθαροτητας

Country Status (14)

Country Link
US (1) US20050020536A1 (el)
EP (1) EP1625135B1 (el)
JP (1) JP4594298B2 (el)
AR (1) AR044200A1 (el)
AT (1) ATE427953T1 (el)
CY (1) CY1109168T1 (el)
DE (1) DE602004020459D1 (el)
DK (1) DK1625135T3 (el)
ES (1) ES2322464T3 (el)
HK (1) HK1087719A1 (el)
PT (1) PT1625135E (el)
SI (1) SI1625135T1 (el)
TW (1) TWI335224B (el)
WO (1) WO2004078105A2 (el)

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US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
WO2006121688A2 (en) * 2005-05-05 2006-11-16 Archipelago Holdings, Inc. Anti-internalization order modifier
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
US8277143B2 (en) * 2009-05-12 2012-10-02 RSA Protective Technology, LLC Surface mount vehicle anti-ram security systems
EP3666786A1 (en) * 2009-07-31 2020-06-17 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
US20130005954A1 (en) * 2011-06-28 2013-01-03 Apicore, Llc Process for preparing heparinoids and intermediates useful in the synthesis thereof
CN102659859B (zh) * 2012-04-11 2014-12-10 苏州纳微科技有限公司 单分散聚甲基丙烯酸酯离子交换层析介质在磺达肝癸钠柱层析纯化中的应用
CN103570774B (zh) * 2012-08-07 2017-08-25 博瑞生物医药（苏州）股份有限公司 一种戊糖化合物的纯化方法
KR102112119B1 (ko) 2012-10-22 2020-05-19 사이덱스 파마슈티칼스, 인크. 알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법
CN103864862B (zh) * 2012-12-14 2017-10-17 博瑞生物医药（苏州）股份有限公司 一种戊糖化合物的纯化方法
US9346844B2 (en) 2013-07-25 2016-05-24 Scinopharm Taiwan, Ltd. Process for the production of fondaparinux sodium
US10072039B2 (en) 2013-07-25 2018-09-11 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium
JP6321798B2 (ja) * 2013-07-25 2018-05-09 サイノファーム タイワン，リミティド フォンダパリヌクスナトリウムを製造するための方法
CN103992364B (zh) * 2014-03-25 2016-08-10 南京天翔医药科技有限公司 一种磺达肝癸钠的分离提取方法
CN103965269B (zh) * 2014-04-16 2018-05-04 杭州华东医药集团新药研究院有限公司 低水分高纯度的磺达肝癸钠及其制备方法
US9873712B2 (en) * 2014-10-03 2018-01-23 Amphastar Pharmaceuticals, Inc. Method of purifying idraparinux sodium
US10688249B2 (en) * 2015-06-11 2020-06-23 Virchow Biotech Pvt. Ltd. Multiple dose pharmaceutical compositions containing heparin and/or heparin-like compounds and devices and methods for delivering the same
CN104910217B (zh) * 2015-06-19 2018-04-17 天津红日药业股份有限公司 用于磺达肝癸钠质量控制的参比化合物
CN105037452B (zh) * 2015-06-19 2018-10-09 天津红日药业股份有限公司 一种快速制备高纯度磺达肝癸钠的精制方法
CN107501359B (zh) * 2017-08-24 2020-07-31 深圳市海滨制药有限公司 一种磺达肝癸钠杂质化合物及其制备方法与应用
CN114478663B (zh) * 2020-11-12 2023-12-01 杭州中美华东制药有限公司 一种磺达肝癸钠杂质的制备方法
CN114591379A (zh) * 2021-12-30 2022-06-07 淮北师范大学 一种磺达肝癸钠甲酰化杂质的制备方法

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JPS5577896A (en) * 1978-12-07 1980-06-12 Meiji Seika Kaisha Ltd Preparation of high-purity maltose
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Also Published As

Publication number Publication date
EP1625135A2 (fr) 2006-02-15
ES2322464T3 (es) 2009-06-22
ATE427953T1 (de) 2009-04-15
WO2004078105A2 (fr) 2004-09-16
EP1625135B1 (fr) 2009-04-08
TWI335224B (en) 2011-01-01
TW200501965A (en) 2005-01-16
WO2004078105A3 (fr) 2004-10-28
AR044200A1 (es) 2005-09-07
JP2006519246A (ja) 2006-08-24
PT1625135E (pt) 2009-07-10
DE602004020459D1 (de) 2009-05-20
DK1625135T3 (da) 2009-06-22
JP4594298B2 (ja) 2010-12-08
SI1625135T1 (sl) 2009-08-31
HK1087719A1 (en) 2006-10-20
US20050020536A1 (en) 2005-01-27

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