CY1109070T1 - Διαδερμικη μορφη δοσολογιας περιλαμβανουσα ενα δραστικο παραγοντα και ενα αλας και μια μορφη ελευθερης βασεως ενος ανταγωνιστη - Google Patents
Διαδερμικη μορφη δοσολογιας περιλαμβανουσα ενα δραστικο παραγοντα και ενα αλας και μια μορφη ελευθερης βασεως ενος ανταγωνιστηInfo
- Publication number
- CY1109070T1 CY1109070T1 CY20091100516T CY091100516T CY1109070T1 CY 1109070 T1 CY1109070 T1 CY 1109070T1 CY 20091100516 T CY20091100516 T CY 20091100516T CY 091100516 T CY091100516 T CY 091100516T CY 1109070 T1 CY1109070 T1 CY 1109070T1
- Authority
- CY
- Cyprus
- Prior art keywords
- salt
- interderative
- free
- animal
- pharmaceutically acceptable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Η παρούσα εφεύρεση αναφέρεται σε μία ανθεκτική σε παρέμβαση διαδερμική μορφή δοσολογίας περιλαμβάνουσα ένα δραστικό παράγοντα, όπως ένα οπιούχο, ή ένα φαρμακευτικά αποδεκτό άλας του, μία ελεύθερη βάση ενός αντίθετου παράγοντα, όπως ενός οπιούχου ανταγωνιστή, και ένα φαρμακευτικά αποδεκτό άλας ενός αντίθετου παράγοντα, όπως ενός οπιούχου ανταγωνιστή. Η διαδερμική μορφή δοσολογίας επιτρέπει τη διαδερμική χορήγηση μίας αποτελεσματικής ποσότητας του δραστικού παράγοντα ή ενός φαρμακευτικά αποδεκτού άλατος του σε ένα ζώο. Η εφεύρεση αναφέρεται περαιτέρω σε μεθόδους για την αγωγή ή την πρόληψη του πόνου σε ένα ζώο περιλαμβάνουσες την επαφή του δέρματος ενός ζώου το οποίο την έχει ανάγκη με τη διαδερμική μορφή δοσολογίας της εφευρέσεως επί χρονικό διάστημα επαρκές για την αγωγή ή την πρόληψη του πόνου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40498002P | 2002-08-20 | 2002-08-20 | |
EP03749093A EP1530469B1 (en) | 2002-08-20 | 2003-08-20 | Transdermal dosage form comprising an active agent and a salt and free-base form of an antagonist |
Publications (1)
Publication Number | Publication Date |
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CY1109070T1 true CY1109070T1 (el) | 2014-07-02 |
Family
ID=31946794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100516T CY1109070T1 (el) | 2002-08-20 | 2009-05-14 | Διαδερμικη μορφη δοσολογιας περιλαμβανουσα ενα δραστικο παραγοντα και ενα αλας και μια μορφη ελευθερης βασεως ενος ανταγωνιστη |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040126323A1 (el) |
EP (1) | EP1530469B1 (el) |
JP (3) | JP4642467B2 (el) |
AT (1) | ATE423560T1 (el) |
AU (1) | AU2003268144A1 (el) |
CY (1) | CY1109070T1 (el) |
DE (1) | DE60326354D1 (el) |
DK (1) | DK1530469T3 (el) |
ES (1) | ES2323127T3 (el) |
PT (1) | PT1530469E (el) |
SI (1) | SI1530469T1 (el) |
WO (1) | WO2004017941A2 (el) |
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-
2003
- 2003-08-20 ES ES03749093T patent/ES2323127T3/es not_active Expired - Lifetime
- 2003-08-20 WO PCT/US2003/026132 patent/WO2004017941A2/en active Application Filing
- 2003-08-20 SI SI200331577T patent/SI1530469T1/sl unknown
- 2003-08-20 JP JP2004531158A patent/JP4642467B2/ja not_active Expired - Fee Related
- 2003-08-20 US US10/645,654 patent/US20040126323A1/en not_active Abandoned
- 2003-08-20 PT PT03749093T patent/PT1530469E/pt unknown
- 2003-08-20 AT AT03749093T patent/ATE423560T1/de active
- 2003-08-20 EP EP03749093A patent/EP1530469B1/en not_active Expired - Lifetime
- 2003-08-20 AU AU2003268144A patent/AU2003268144A1/en not_active Abandoned
- 2003-08-20 DK DK03749093T patent/DK1530469T3/da active
- 2003-08-20 DE DE60326354T patent/DE60326354D1/de not_active Expired - Lifetime
-
2009
- 2009-05-14 CY CY20091100516T patent/CY1109070T1/el unknown
-
2010
- 2010-03-09 JP JP2010051569A patent/JP5329461B2/ja not_active Expired - Fee Related
- 2010-09-30 JP JP2010220518A patent/JP5437214B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2323127T3 (es) | 2009-07-07 |
JP4642467B2 (ja) | 2011-03-02 |
PT1530469E (pt) | 2009-05-19 |
US20040126323A1 (en) | 2004-07-01 |
AU2003268144A8 (en) | 2004-03-11 |
ATE423560T1 (de) | 2009-03-15 |
JP5329461B2 (ja) | 2013-10-30 |
DE60326354D1 (de) | 2009-04-09 |
JP2006501241A (ja) | 2006-01-12 |
EP1530469B1 (en) | 2009-02-25 |
SI1530469T1 (sl) | 2009-06-30 |
WO2004017941A3 (en) | 2004-04-22 |
JP2010163446A (ja) | 2010-07-29 |
JP2011021029A (ja) | 2011-02-03 |
JP5437214B2 (ja) | 2014-03-12 |
AU2003268144A1 (en) | 2004-03-11 |
WO2004017941A2 (en) | 2004-03-04 |
EP1530469A2 (en) | 2005-05-18 |
DK1530469T3 (da) | 2009-05-04 |
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