CY1108863T1 - Φαρμακευτικο σκευασμα εκτεταμενης απελευθερωσης ανεξαρτητης απο το ρη - Google Patents
Φαρμακευτικο σκευασμα εκτεταμενης απελευθερωσης ανεξαρτητης απο το ρηInfo
- Publication number
- CY1108863T1 CY1108863T1 CY20091100254T CY091100254T CY1108863T1 CY 1108863 T1 CY1108863 T1 CY 1108863T1 CY 20091100254 T CY20091100254 T CY 20091100254T CY 091100254 T CY091100254 T CY 091100254T CY 1108863 T1 CY1108863 T1 CY 1108863T1
- Authority
- CY
- Cyprus
- Prior art keywords
- weight percent
- tablet
- pharmaceutical preparation
- independent release
- water
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 238000005469 granulation Methods 0.000 abstract 2
- 230000003179 granulation Effects 0.000 abstract 2
- 239000002831 pharmacologic agent Substances 0.000 abstract 2
- 229940028937 divalproex sodium Drugs 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- MSRILKIQRXUYCT-UHFFFAOYSA-M valproate semisodium Chemical compound [Na+].CCCC(C(O)=O)CCC.CCCC(C([O-])=O)CCC MSRILKIQRXUYCT-UHFFFAOYSA-M 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24467899A | 1999-02-04 | 1999-02-04 | |
| EP00904586A EP1146864B1 (en) | 1999-02-04 | 2000-01-26 | Ph independent extended release pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108863T1 true CY1108863T1 (el) | 2014-07-02 |
Family
ID=22923698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100254T CY1108863T1 (el) | 1999-02-04 | 2009-03-06 | Φαρμακευτικο σκευασμα εκτεταμενης απελευθερωσης ανεξαρτητης απο το ρη |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1146864B1 (enExample) |
| JP (2) | JP5420126B2 (enExample) |
| AT (1) | ATE424191T1 (enExample) |
| CA (1) | CA2361496C (enExample) |
| CY (1) | CY1108863T1 (enExample) |
| DE (1) | DE60041691D1 (enExample) |
| DK (1) | DK1146864T3 (enExample) |
| ES (1) | ES2321908T3 (enExample) |
| PT (1) | PT1146864E (enExample) |
| WO (1) | WO2000045793A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713086B2 (en) | 1998-12-18 | 2004-03-30 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
| US6528090B2 (en) | 1998-12-18 | 2003-03-04 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
| US20020025341A1 (en) * | 1998-12-18 | 2002-02-28 | Yihong Qiu | Controlled release formulation of divalproex sodium |
| US6419953B1 (en) | 1998-12-18 | 2002-07-16 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
| US6511678B2 (en) | 1998-12-18 | 2003-01-28 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
| WO2002051402A1 (en) * | 2000-12-22 | 2002-07-04 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
| GB0102342D0 (en) * | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| WO2004071421A2 (en) * | 2003-02-05 | 2004-08-26 | Teva Pharmaceutical Industries Ltd. | Sustained release formulation of n-(2-propylpentanoyl) glycinamide and related compounds |
| US8920837B2 (en) | 2005-07-01 | 2014-12-30 | Rubicon Research Private Limited | Sustained release dosage form |
| US20100255099A1 (en) * | 2007-10-26 | 2010-10-07 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
| CN107811985B (zh) * | 2016-09-13 | 2021-05-28 | 四川科瑞德制药股份有限公司 | 一种抗癫痫缓释制剂及其制备方法与用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL72381A (en) * | 1983-07-20 | 1988-03-31 | Sanofi Sa | Pharmaceutical composition based on valproic acid |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| DE3809764A1 (de) * | 1988-03-23 | 1989-10-05 | Knoll Ag | Mischung aus alginaten und polyacrylaten und deren verwendung |
| FR2643556B1 (fr) * | 1989-02-27 | 1993-03-05 | Sanofi Sa | Composition pharmaceutique a liberation prolongee d'acide valproique |
| US5102668A (en) * | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
| AU6824996A (en) * | 1995-08-17 | 1997-03-12 | Dyer, Alison Margaret | Controlled release products |
| AUPN969796A0 (en) * | 1996-05-07 | 1996-05-30 | F.H. Faulding & Co. Limited | Taste masked liquid suspensions |
| CA2254078A1 (en) * | 1997-03-11 | 1998-09-17 | Hexal Ag | Solid, non-deliquescent formulations of sodium valproate |
-
2000
- 2000-01-26 WO PCT/US2000/001954 patent/WO2000045793A1/en not_active Ceased
- 2000-01-26 JP JP2000596913A patent/JP5420126B2/ja not_active Expired - Lifetime
- 2000-01-26 EP EP00904586A patent/EP1146864B1/en not_active Expired - Lifetime
- 2000-01-26 AT AT00904586T patent/ATE424191T1/de active
- 2000-01-26 DK DK00904586T patent/DK1146864T3/da active
- 2000-01-26 PT PT00904586T patent/PT1146864E/pt unknown
- 2000-01-26 CA CA2361496A patent/CA2361496C/en not_active Expired - Fee Related
- 2000-01-26 ES ES00904586T patent/ES2321908T3/es not_active Expired - Lifetime
- 2000-01-26 DE DE60041691T patent/DE60041691D1/de not_active Expired - Lifetime
-
2009
- 2009-03-06 CY CY20091100254T patent/CY1108863T1/el unknown
-
2011
- 2011-05-24 JP JP2011116089A patent/JP5420590B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1146864A1 (en) | 2001-10-24 |
| JP5420590B2 (ja) | 2014-02-19 |
| JP5420126B2 (ja) | 2014-02-19 |
| WO2000045793A1 (en) | 2000-08-10 |
| CA2361496C (en) | 2011-06-07 |
| JP2011241218A (ja) | 2011-12-01 |
| DK1146864T3 (da) | 2009-05-11 |
| JP2002536318A (ja) | 2002-10-29 |
| ATE424191T1 (de) | 2009-03-15 |
| CA2361496A1 (en) | 2000-08-10 |
| EP1146864B1 (en) | 2009-03-04 |
| PT1146864E (pt) | 2009-03-20 |
| ES2321908T3 (es) | 2009-06-15 |
| DE60041691D1 (de) | 2009-04-16 |
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