CY1108730T1 - Θεραπεια ασθενειας hundington με epa - Google Patents
Θεραπεια ασθενειας hundington με epaInfo
- Publication number
- CY1108730T1 CY1108730T1 CY20091100029T CY091100029T CY1108730T1 CY 1108730 T1 CY1108730 T1 CY 1108730T1 CY 20091100029 T CY20091100029 T CY 20091100029T CY 091100029 T CY091100029 T CY 091100029T CY 1108730 T1 CY1108730 T1 CY 1108730T1
- Authority
- CY
- Cyprus
- Prior art keywords
- epa
- hundington
- disease treatment
- huntington
- disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Ανάλυση γονιδίου Hundington παρέχει μέθοδο πιστοποίησης ασθενών που πιθανώς ανταποκρίνονται σε θεραπεία ασθένειας Hundington με εικοσαπενταενοϊκό οξύ, EPA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0228079.0A GB0228079D0 (en) | 2002-12-02 | 2002-12-02 | Huntington's Disease |
EP03778516A EP1567667B1 (en) | 2002-12-02 | 2003-11-26 | Treatment of huntington's disease with epa |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108730T1 true CY1108730T1 (el) | 2014-04-09 |
Family
ID=9948921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100029T CY1108730T1 (el) | 2002-12-02 | 2009-01-14 | Θεραπεια ασθενειας hundington με epa |
Country Status (29)
Country | Link |
---|---|
US (2) | US20070148643A1 (el) |
EP (1) | EP1567667B1 (el) |
JP (1) | JP2006507833A (el) |
KR (1) | KR20050086895A (el) |
CN (1) | CN1717497A (el) |
AT (1) | ATE411399T1 (el) |
AU (1) | AU2003285519A1 (el) |
BR (1) | BR0316969A (el) |
CA (1) | CA2506727A1 (el) |
CY (1) | CY1108730T1 (el) |
DE (1) | DE60324180D1 (el) |
DK (1) | DK1567667T3 (el) |
ES (1) | ES2315543T3 (el) |
GB (1) | GB0228079D0 (el) |
HK (1) | HK1081598A1 (el) |
HR (1) | HRP20050493A2 (el) |
IS (1) | IS7842A (el) |
MX (1) | MXPA05005908A (el) |
MY (1) | MY138759A (el) |
NO (1) | NO20052955L (el) |
NZ (1) | NZ539989A (el) |
PL (1) | PL376101A1 (el) |
PT (1) | PT1567667E (el) |
RU (1) | RU2332209C2 (el) |
SI (1) | SI1567667T1 (el) |
TW (1) | TWI306120B (el) |
UA (1) | UA86582C2 (el) |
WO (1) | WO2004050913A1 (el) |
ZA (1) | ZA200504003B (el) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007524674A (ja) * | 2004-01-19 | 2007-08-30 | マーテック・バイオサイエンシーズ・コーポレーション | リーリン欠損症または機能障害およびそれに関連する方法 |
WO2007123391A1 (en) | 2006-04-20 | 2007-11-01 | Academisch Ziekenhuis Leiden | Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene. |
EP1857548A1 (en) | 2006-05-19 | 2007-11-21 | Academisch Ziekenhuis Leiden | Means and method for inducing exon-skipping |
DK2049664T3 (da) | 2006-08-11 | 2012-01-02 | Prosensa Technologies Bv | Enkeltstrengede oligonukleotider, som er komplementære til repetitive elementer, til behandling af med DNA-repetitiv-ustabilitet associerede lidelser |
JP5706157B2 (ja) | 2007-07-12 | 2015-04-22 | プロセンサ テクノロジーズ ビー.ブイ.Prosensa Technologies B.V. | 化合物を種々の選択臓器又は組織に標的化するための分子 |
JP2010533170A (ja) | 2007-07-12 | 2010-10-21 | プロセンサ テクノロジーズ ビー.ブイ. | 化合物を種々の選択された臓器、組織又は腫瘍細胞に標的化するための分子 |
EP2203173B1 (en) | 2007-10-26 | 2015-12-23 | Academisch Ziekenhuis Leiden | Means and methods for counteracting muscle disorders |
USRE48468E1 (en) | 2007-10-26 | 2021-03-16 | Biomarin Technologies B.V. | Means and methods for counteracting muscle disorders |
WO2009099326A1 (en) | 2008-02-08 | 2009-08-13 | Prosensa Holding Bv | Methods and means for treating dna repeat instability associated genetic disorders |
EP2119783A1 (en) | 2008-05-14 | 2009-11-18 | Prosensa Technologies B.V. | Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means |
EP3187182B1 (en) | 2008-09-02 | 2021-03-03 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same |
PT3037089T (pt) | 2009-02-10 | 2020-03-04 | Amarin Pharmaceuticals Ie Ltd | Ester etílico de ácido eicosapentaenoico para tratamento de hipertrigliceridemia |
US20120046342A1 (en) | 2009-04-24 | 2012-02-23 | Prosensa Technologies B.V. | Oligonucleotide comprising an inosine for treating dmd |
RU2624506C2 (ru) | 2009-04-29 | 2017-07-04 | АМАРИН КОРПОРЕЙШН ПиЭлСи | Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способы их применения |
EP2424356B1 (en) | 2009-04-29 | 2017-08-23 | Amarin Pharmaceuticals Ireland Limited | Stable pharmaceutical composition and methods of using same |
EP3698781A1 (en) | 2009-06-15 | 2020-08-26 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid for treating myocardial infarction in a subject on concomitant statin therapy |
RU2012116079A (ru) | 2009-09-23 | 2013-10-27 | АМАРИН КОРПОРЕЙШН ПиЭлСи | Фармацевтическая композиция, включающая омега-3 жирную кислоту и гидроксипроизводное статина и способы ее применения |
JP6141018B2 (ja) | 2009-12-24 | 2017-06-07 | バイオマリン テクノロジーズ ベー.フェー. | 炎症性障害を治療するための分子 |
US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
NZ744990A (en) | 2010-11-29 | 2019-10-25 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
EP2775837A4 (en) | 2011-11-07 | 2015-10-28 | Amarin Pharmaceuticals Ie Ltd | METHODS OF TREATING HYPERTRIGLYCERIDEMIA |
JP6307442B2 (ja) | 2012-01-06 | 2018-04-04 | アマリン ファーマシューティカルス アイルランド リミテッド | 対象の高感度(hs−crp)のレベルを低下させる組成物および方法 |
CN104203289B (zh) | 2012-01-27 | 2020-11-03 | 比奥马林技术公司 | 用于治疗杜兴型肌营养不良症和贝克型肌营养不良症的具有改善特性的rna调节性寡核苷酸 |
PT3363433T (pt) | 2012-06-29 | 2021-02-15 | Amarin Pharmaceuticals Ie Ltd | Métodos de redução do risco de um episódio cardiovascular num indivíduo em terapia com estatina utilizando éster etílico do ácido eicosapentaenoico |
WO2014074552A2 (en) | 2012-11-06 | 2014-05-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy |
US9814733B2 (en) | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
US9624492B2 (en) | 2013-02-13 | 2017-04-18 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof |
US9662307B2 (en) | 2013-02-19 | 2017-05-30 | The Regents Of The University Of Colorado | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof |
US9283201B2 (en) | 2013-03-14 | 2016-03-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating or preventing obesity in a subject in need thereof |
US20140271841A1 (en) | 2013-03-15 | 2014-09-18 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin |
US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
US20150065572A1 (en) | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
US9585859B2 (en) | 2013-10-10 | 2017-03-07 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy |
US10561631B2 (en) | 2014-06-11 | 2020-02-18 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing RLP-C |
WO2015195662A1 (en) | 2014-06-16 | 2015-12-23 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids |
US10406130B2 (en) | 2016-03-15 | 2019-09-10 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
WO2018213663A1 (en) | 2017-05-19 | 2018-11-22 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject having reduced kidney function |
US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
SG11202102872QA (en) | 2018-09-24 | 2021-04-29 | Amarin Pharmaceuticals Ie Ltd | Methods of reducing the risk of cardiovascular events in a subject |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2116280A1 (en) * | 1993-03-05 | 1994-09-06 | Marcy E. Macdonald | Huntingtin dna, protein and uses thereof |
CA2216057A1 (en) * | 1997-09-19 | 1999-03-19 | Ridha Joober | Polymorphic cag repeat-containing gene, diagnosis of psychiatric diseases and therapeutic uses thereof |
GB9901809D0 (en) * | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
JP2003510349A (ja) * | 1999-10-07 | 2003-03-18 | ノヴァ−ニューロン インコーポレーテッド | 線条体機能に必要な遺伝子、その使用、およびそれを調節するための化合物 |
-
2002
- 2002-12-02 GB GBGB0228079.0A patent/GB0228079D0/en not_active Ceased
-
2003
- 2003-11-21 MY MYPI20034492A patent/MY138759A/en unknown
- 2003-11-26 UA UAA200505201A patent/UA86582C2/ru unknown
- 2003-11-26 EP EP03778516A patent/EP1567667B1/en not_active Expired - Lifetime
- 2003-11-26 BR BR0316969-3A patent/BR0316969A/pt not_active IP Right Cessation
- 2003-11-26 DK DK03778516T patent/DK1567667T3/da active
- 2003-11-26 WO PCT/GB2003/005131 patent/WO2004050913A1/en active Application Filing
- 2003-11-26 JP JP2004556479A patent/JP2006507833A/ja active Pending
- 2003-11-26 NZ NZ539989A patent/NZ539989A/en unknown
- 2003-11-26 ES ES03778516T patent/ES2315543T3/es not_active Expired - Lifetime
- 2003-11-26 PT PT03778516T patent/PT1567667E/pt unknown
- 2003-11-26 RU RU2005115536/14A patent/RU2332209C2/ru not_active IP Right Cessation
- 2003-11-26 MX MXPA05005908A patent/MXPA05005908A/es active IP Right Grant
- 2003-11-26 SI SI200331472T patent/SI1567667T1/sl unknown
- 2003-11-26 PL PL03376101A patent/PL376101A1/xx unknown
- 2003-11-26 DE DE60324180T patent/DE60324180D1/de not_active Expired - Lifetime
- 2003-11-26 AU AU2003285519A patent/AU2003285519A1/en not_active Abandoned
- 2003-11-26 CA CA002506727A patent/CA2506727A1/en not_active Abandoned
- 2003-11-26 AT AT03778516T patent/ATE411399T1/de not_active IP Right Cessation
- 2003-11-26 CN CNA2003801044204A patent/CN1717497A/zh active Pending
- 2003-11-26 US US10/536,927 patent/US20070148643A1/en not_active Abandoned
- 2003-11-26 KR KR1020057009802A patent/KR20050086895A/ko not_active Application Discontinuation
- 2003-11-26 TW TW092133160A patent/TWI306120B/zh active
-
2005
- 2005-05-12 IS IS7842A patent/IS7842A/is unknown
- 2005-05-18 ZA ZA200504003A patent/ZA200504003B/en unknown
- 2005-06-02 HR HR20050493A patent/HRP20050493A2/xx not_active Application Discontinuation
- 2005-06-16 NO NO20052955A patent/NO20052955L/no not_active Application Discontinuation
-
2006
- 2006-02-02 HK HK06101406A patent/HK1081598A1/xx not_active IP Right Cessation
-
2009
- 2009-01-14 CY CY20091100029T patent/CY1108730T1/el unknown
- 2009-04-24 US US12/429,825 patent/US20090270504A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2315543T3 (es) | 2009-04-01 |
WO2004050913A1 (en) | 2004-06-17 |
ATE411399T1 (de) | 2008-10-15 |
GB0228079D0 (en) | 2003-01-08 |
TWI306120B (en) | 2009-02-11 |
AU2003285519A1 (en) | 2004-06-23 |
ZA200504003B (en) | 2007-01-31 |
NZ539989A (en) | 2006-11-30 |
US20090270504A1 (en) | 2009-10-29 |
DK1567667T3 (da) | 2009-01-12 |
UA86582C2 (ru) | 2009-05-12 |
HRP20050493A2 (en) | 2005-10-31 |
US20070148643A1 (en) | 2007-06-28 |
SI1567667T1 (sl) | 2009-04-30 |
MY138759A (en) | 2009-07-31 |
TW200418993A (en) | 2004-10-01 |
CA2506727A1 (en) | 2004-06-17 |
BR0316969A (pt) | 2005-10-25 |
RU2332209C2 (ru) | 2008-08-27 |
RU2005115536A (ru) | 2006-01-27 |
EP1567667A1 (en) | 2005-08-31 |
EP1567667B1 (en) | 2008-10-15 |
JP2006507833A (ja) | 2006-03-09 |
PL376101A1 (en) | 2005-12-12 |
KR20050086895A (ko) | 2005-08-30 |
NO20052955L (no) | 2005-06-16 |
IS7842A (is) | 2005-05-12 |
CN1717497A (zh) | 2006-01-04 |
MXPA05005908A (es) | 2005-12-12 |
DE60324180D1 (de) | 2008-11-27 |
HK1081598A1 (en) | 2006-05-19 |
PT1567667E (pt) | 2008-11-04 |
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