CY1108099T1 - Ενωσεις αμμωνιου κυκλοδεξτρινης μετατραπεισες σε τετρατοταγη δομη - Google Patents

Ενωσεις αμμωνιου κυκλοδεξτρινης μετατραπεισες σε τετρατοταγη δομη

Info

Publication number
CY1108099T1
CY1108099T1 CY20081100523T CY081100523T CY1108099T1 CY 1108099 T1 CY1108099 T1 CY 1108099T1 CY 20081100523 T CY20081100523 T CY 20081100523T CY 081100523 T CY081100523 T CY 081100523T CY 1108099 T1 CY1108099 T1 CY 1108099T1
Authority
CY
Cyprus
Prior art keywords
compound
cyclodextrine
ammonium
square surface
formula
Prior art date
Application number
CY20081100523T
Other languages
Greek (el)
English (en)
Inventor
Georg Ludwig Kis
Christian Schoch
Jozsef Szejtli
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1108099T1 publication Critical patent/CY1108099T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CY20081100523T 2002-06-13 2008-05-20 Ενωσεις αμμωνιου κυκλοδεξτρινης μετατραπεισες σε τετρατοταγη δομη CY1108099T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02013074 2002-06-13
EP02028554 2002-12-20
EP03740232A EP1515729B1 (en) 2002-06-13 2003-06-12 Quaternised ammonium cyclodextrin compounds

Publications (1)

Publication Number Publication Date
CY1108099T1 true CY1108099T1 (el) 2014-02-12

Family

ID=29737927

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100523T CY1108099T1 (el) 2002-06-13 2008-05-20 Ενωσεις αμμωνιου κυκλοδεξτρινης μετατραπεισες σε τετρατοταγη δομη

Country Status (15)

Country Link
US (4) US20050222085A1 (enExample)
EP (1) EP1515729B1 (enExample)
JP (2) JP4773721B2 (enExample)
CN (1) CN100589809C (enExample)
AT (1) ATE386532T1 (enExample)
AU (1) AU2003276957A1 (enExample)
BR (1) BR0311722A (enExample)
CA (1) CA2487332C (enExample)
CY (1) CY1108099T1 (enExample)
DE (1) DE60319221T2 (enExample)
DK (1) DK1515729T3 (enExample)
ES (1) ES2301807T3 (enExample)
PT (1) PT1515729E (enExample)
SI (1) SI1515729T1 (enExample)
WO (1) WO2003105867A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100678824B1 (ko) * 2005-02-04 2007-02-05 한미약품 주식회사 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물
BRPI0709409A2 (pt) 2006-03-28 2011-07-12 Javelin Pharmaceuticals Inc composição farmacêutica e método para tratar um mamìfero necessitando de analgesia
WO2008120249A1 (en) * 2007-03-30 2008-10-09 Sifi S.P.A. Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
CN101757621B (zh) * 2008-11-28 2012-07-04 天津金耀集团有限公司 一种眼部抗炎的环糊精包合药物组合物
US9642920B2 (en) * 2009-06-03 2017-05-09 Case Western Reserve University Therapeutic agent delivery system and method
CN102276761A (zh) * 2010-06-11 2011-12-14 南京理工大学 单取代铵基正电型-β-环糊精及其制备方法
GB201114459D0 (en) * 2011-08-22 2011-10-05 Isis Innovation Anti-bacterial compounds
CN103497275B (zh) * 2013-08-09 2015-12-23 华北电力大学(保定) 一种抗菌、抗病毒胍盐星形聚合物及其制备方法和应用
CZ307458B6 (cs) * 2014-11-25 2018-09-12 Spur A.S. Vícevrstvý kryt rány s aktivní vrstvou a způsob jeho výroby
EP3227379B1 (en) * 2014-12-02 2020-07-29 B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University Quaternized starches for use as anti-microbial agents
CN109487588B (zh) * 2018-11-19 2021-04-20 绍兴永通印花有限公司 一种印花用涤纶织物处理液及其使用方法
BR112021014889A2 (pt) * 2019-02-14 2021-10-05 Cyclopure, Inc. Materiais poliméricos de ciclodextrina com carga e métodos de fabricação e uso dos mesmos
CN109836512A (zh) * 2019-03-04 2019-06-04 西南石油大学 一种新型β-CD双子表面活性剂为稠化剂的清洁压裂液
CN112386710A (zh) * 2020-12-09 2021-02-23 星拜(苏州)生物科技有限公司 一种利用包埋技术改善紫檀芪水溶性的方法
CN116987213B (zh) * 2022-04-26 2025-09-09 中国石油化工股份有限公司 一种具有表面活性剂功能的化合物、一种表面活性剂及其制备方法
CN120435346A (zh) 2023-01-12 2025-08-05 赛克洛珀股份有限公司 聚合环糊精吸附剂的再生

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453257A (en) * 1967-02-13 1969-07-01 Corn Products Co Cyclodextrin with cationic properties
JPS58210901A (ja) * 1982-06-01 1983-12-08 Kao Corp シクロデキストリン誘導体およびその製造方法
IT1229133B (it) * 1989-03-09 1991-07-22 Farmhispania Sali ammonici di policiclodestrine per l'impiego come agenti ipocolesterolemizzanti
KR927003645A (ko) * 1990-05-21 1992-12-18 후지다 히로미찌 씨클로덱스트린 유도체
JPH0481401A (ja) * 1990-07-24 1992-03-16 Toppan Printing Co Ltd シクロデキストリン誘導体
JPH0665307A (ja) * 1992-06-17 1994-03-08 Sankyo Co Ltd シクロデキストリン誘導体
US5891913A (en) * 1994-10-10 1999-04-06 Novartis Finance Corporation Ophthalmic and aural compositions containing diclofenac potassium
JP3297969B2 (ja) * 1994-12-26 2002-07-02 ライオン株式会社 点眼剤
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
TW434023B (en) * 1995-09-18 2001-05-16 Novartis Ag Preserved ophthalmic composition
NZ505951A (en) * 1998-02-23 2003-02-28 Cyclops Ehf A method for enhancing the complexation efficiency of a heterocyclic drug with cyclodextrin, by subjecting the heterocycloc drug to chemically reversible ring-opening

Also Published As

Publication number Publication date
CN100589809C (zh) 2010-02-17
JP2005529175A (ja) 2005-09-29
US20050222085A1 (en) 2005-10-06
SI1515729T1 (sl) 2008-08-31
BR0311722A (pt) 2005-03-01
US20090110734A1 (en) 2009-04-30
ATE386532T1 (de) 2008-03-15
US20130137657A1 (en) 2013-05-30
PT1515729E (pt) 2008-05-30
DK1515729T3 (da) 2008-06-16
AU2003276957A1 (en) 2003-12-31
WO2003105867A1 (en) 2003-12-24
JP4773721B2 (ja) 2011-09-14
EP1515729B1 (en) 2008-02-20
CA2487332C (en) 2012-05-15
US20120004158A1 (en) 2012-01-05
DE60319221D1 (de) 2008-04-03
JP2011006448A (ja) 2011-01-13
CA2487332A1 (en) 2003-12-24
DE60319221T2 (de) 2009-03-05
ES2301807T3 (es) 2008-07-01
CN1658888A (zh) 2005-08-24
EP1515729A1 (en) 2005-03-23

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