CY1107612T1 - Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους - Google Patents

Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους

Info

Publication number
CY1107612T1
CY1107612T1 CY20071100489T CY071100489T CY1107612T1 CY 1107612 T1 CY1107612 T1 CY 1107612T1 CY 20071100489 T CY20071100489 T CY 20071100489T CY 071100489 T CY071100489 T CY 071100489T CY 1107612 T1 CY1107612 T1 CY 1107612T1
Authority
CY
Cyprus
Prior art keywords
morphine sulfate
morphokes
compositions
preparation
granules
Prior art date
Application number
CY20071100489T
Other languages
Greek (el)
English (en)
Inventor
Dominique Marechal
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9546553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107612(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm filed Critical Ethypharm
Publication of CY1107612T1 publication Critical patent/CY1107612T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CY20071100489T 1999-06-09 2007-04-05 Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους CY1107612T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9907259A FR2794646B1 (fr) 1999-06-09 1999-06-09 Microgranules de sulfate de morphine, procede de preparation et composition les contenant
EP00940460A EP1189602B1 (fr) 1999-06-09 2000-06-08 Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Publications (1)

Publication Number Publication Date
CY1107612T1 true CY1107612T1 (el) 2013-03-13

Family

ID=9546553

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100489T CY1107612T1 (el) 1999-06-09 2007-04-05 Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους

Country Status (24)

Country Link
US (2) US7063864B1 (cg-RX-API-DMAC7.html)
EP (3) EP1627631B1 (cg-RX-API-DMAC7.html)
JP (1) JP4296562B2 (cg-RX-API-DMAC7.html)
KR (1) KR100676123B1 (cg-RX-API-DMAC7.html)
CN (1) CN1267089C (cg-RX-API-DMAC7.html)
AR (2) AR024313A1 (cg-RX-API-DMAC7.html)
AT (2) ATE544448T1 (cg-RX-API-DMAC7.html)
AU (1) AU769160C (cg-RX-API-DMAC7.html)
BR (1) BRPI0011404B8 (cg-RX-API-DMAC7.html)
CA (1) CA2376339C (cg-RX-API-DMAC7.html)
CO (1) CO5160317A1 (cg-RX-API-DMAC7.html)
CY (1) CY1107612T1 (cg-RX-API-DMAC7.html)
DE (1) DE60033519T2 (cg-RX-API-DMAC7.html)
DK (2) DK1189602T3 (cg-RX-API-DMAC7.html)
ES (2) ES2280226T3 (cg-RX-API-DMAC7.html)
FR (1) FR2794646B1 (cg-RX-API-DMAC7.html)
HK (1) HK1045107B (cg-RX-API-DMAC7.html)
MX (1) MXPA01012751A (cg-RX-API-DMAC7.html)
NZ (1) NZ516077A (cg-RX-API-DMAC7.html)
PT (2) PT1627631E (cg-RX-API-DMAC7.html)
SI (1) SI1189602T1 (cg-RX-API-DMAC7.html)
TW (1) TWI224510B (cg-RX-API-DMAC7.html)
WO (1) WO2000074659A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200110087B (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
JP4848101B2 (ja) * 2001-08-17 2011-12-28 株式会社フジモト・コーポレーション 徐放性マイクロペレット
EP1429739A1 (en) 2001-09-21 2004-06-23 Egalet A/S Polymer release system
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
ES2570454T3 (es) 2003-03-26 2016-05-18 Egalet Ltd Sistema de liberación controlada de morfina
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
WO2008148798A2 (en) 2007-06-04 2008-12-11 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
AU2010211220B2 (en) 2009-02-06 2013-08-01 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
CA2766179A1 (en) 2009-06-24 2010-12-29 Egalet Ltd. Controlled release formulations
US20190038769A1 (en) * 2010-12-01 2019-02-07 Gowey Research Group, Pllc Micro-rna profiling, compositions, and methods of treating diseases
JP2012250926A (ja) * 2011-06-01 2012-12-20 Nitto Denko Corp 粒子製剤
KR20150059167A (ko) 2012-07-06 2015-05-29 에갈렛 리미티드 제어된 방출을 위한 남용 제지 약학적 조성물
AU2018390826B2 (en) 2017-12-20 2024-09-12 Purdue Pharma L.P. Abuse deterrent morphine sulfate dosage forms

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8514665D0 (en) 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
CA2007181C (en) 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
GB9119958D0 (en) 1991-09-18 1991-10-30 Unilever Plc Detergent compositions
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5286493A (en) 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
SE9301057L (sv) 1993-03-30 1994-10-01 Pharmacia Ab Beredning med kontrollerad frisättning
HU218673B (hu) * 1993-10-07 2000-10-28 Euroceltique S.A. Opioid analgetikumot tartalmazó elnyújtott hatóanyag-felszabadítású orális gyógyszerkészítmény és eljárás előállítására
US5411745A (en) 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
US5460826A (en) 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
FR2771291B1 (fr) 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Also Published As

Publication number Publication date
JP4296562B2 (ja) 2009-07-15
AU5539400A (en) 2000-12-28
FR2794646B1 (fr) 2001-09-21
DE60033519D1 (de) 2007-04-05
DE60033519T2 (de) 2007-10-31
US7063864B1 (en) 2006-06-20
AU769160C (en) 2006-02-23
EP1189602A1 (fr) 2002-03-27
PT1627631E (pt) 2012-05-21
BRPI0011404B8 (pt) 2021-05-25
EP1627631A3 (fr) 2006-03-15
CN1267089C (zh) 2006-08-02
AU769160B2 (en) 2004-01-15
EP1627631B1 (fr) 2012-02-08
DK1189602T3 (da) 2007-07-02
MXPA01012751A (es) 2002-07-02
KR20020031338A (ko) 2002-05-01
ATE544448T1 (de) 2012-02-15
DK1627631T3 (da) 2012-04-30
EP1627631A2 (fr) 2006-02-22
PT1189602E (pt) 2007-05-31
CO5160317A1 (es) 2002-05-30
NZ516077A (en) 2004-06-25
TWI224510B (en) 2004-12-01
WO2000074659A1 (fr) 2000-12-14
KR100676123B1 (ko) 2007-01-31
CA2376339A1 (fr) 2000-12-14
ES2379688T3 (es) 2012-04-30
SI1189602T1 (sl) 2007-06-30
HK1045107A1 (en) 2002-11-15
US20070003620A1 (en) 2007-01-04
ZA200110087B (en) 2003-03-03
BR0011404A (pt) 2002-03-05
AR024313A1 (es) 2002-09-25
BR0011404B1 (pt) 2013-03-05
FR2794646A1 (fr) 2000-12-15
ES2280226T3 (es) 2007-09-16
AR068015A2 (es) 2009-10-28
CA2376339C (fr) 2011-05-17
EP1818051A1 (fr) 2007-08-15
ATE354356T1 (de) 2007-03-15
HK1045107B (zh) 2007-05-11
JP2003520770A (ja) 2003-07-08
EP1189602B1 (fr) 2007-02-21
CN1390121A (zh) 2003-01-08

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