CU22776A3 - D-manitol y su preparación - Google Patents

D-manitol y su preparación

Info

Publication number
CU22776A3
CU22776A3 CU1998154A CU1998154A CU22776A3 CU 22776 A3 CU22776 A3 CU 22776A3 CU 1998154 A CU1998154 A CU 1998154A CU 1998154 A CU1998154 A CU 1998154A CU 22776 A3 CU22776 A3 CU 22776A3
Authority
CU
Cuba
Prior art keywords
preparation
manitol
mannitol
understandability
excipient
Prior art date
Application number
CU1998154A
Other languages
English (en)
Inventor
Shinji Maegata
Tomohiro Yoshinari
Norbert Poellinger
Fritz Schueeckler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14109240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU22776(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CU22776A3 publication Critical patent/CU22776A3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención trata de un nuevo D-manitol y su preparación. De forma más específica, trata de un D-manitol que puede utilizarse como excipiente con una excelente comprensibilidad, en los campos de la apreparación de medicamentos y la industria de procesamiento de alimentos, y un procedimiento para su preparación.
CU1998154A 1996-04-16 1998-10-16 D-manitol y su preparación CU22776A3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9440196 1996-04-16

Publications (1)

Publication Number Publication Date
CU22776A3 true CU22776A3 (es) 2002-07-24

Family

ID=14109240

Family Applications (1)

Application Number Title Priority Date Filing Date
CU1998154A CU22776A3 (es) 1996-04-16 1998-10-16 D-manitol y su preparación

Country Status (27)

Country Link
US (1) US6503918B2 (es)
EP (1) EP0902777B2 (es)
KR (1) KR20000005486A (es)
CN (1) CN1221398A (es)
AT (1) ATE202768T1 (es)
AU (1) AU718658B2 (es)
BG (1) BG63460B1 (es)
BR (1) BR9708672A (es)
CA (1) CA2251092A1 (es)
CU (1) CU22776A3 (es)
CZ (1) CZ333698A3 (es)
DE (1) DE69705516T3 (es)
DK (1) DK0902777T4 (es)
EA (1) EA000968B1 (es)
ES (1) ES2158540T5 (es)
GR (1) GR3036760T3 (es)
HU (1) HUP9902165A3 (es)
ID (1) ID16566A (es)
IL (1) IL126580A (es)
NO (2) NO311349B1 (es)
NZ (1) NZ332313A (es)
PL (1) PL329614A1 (es)
PT (1) PT902777E (es)
SK (1) SK282768B6 (es)
TR (1) TR199802079T2 (es)
TW (1) TW515787B (es)
WO (1) WO1997038960A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10008506A1 (de) * 2000-02-24 2001-09-13 Bayer Ag Verfahren zur Herstellung von pharmazeutischen Darreichungsformen
FR2807034B1 (fr) † 2000-03-29 2002-06-14 Roquette Freres Mannitol pulverulent et son procede de fabrication
CN1247188C (zh) * 2000-09-19 2006-03-29 第一制药株式会社 药物组合物
US6979462B1 (en) * 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
US6855333B1 (en) 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
ES2752452T3 (es) * 2002-05-14 2020-04-06 Dupont Nutrition Usa Inc Composiciones de hidrocoloides de celulosa microcristalinas codesgastadas por atrición y método para su fabricación
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
WO2007074856A1 (ja) 2005-12-28 2007-07-05 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤の製造法
SG183583A1 (en) 2006-02-20 2012-09-27 Chugai Pharmaceutical Co Ltd Pharmaceutical composition comprising oseltamivir phosphate
JP2010507676A (ja) * 2006-10-27 2010-03-11 エフ エム シー コーポレーション 乾式顆粒化結合剤、生成物およびその使用
CA2680536A1 (en) 2007-03-13 2008-10-09 Dainippon Sumitomo Pharma Co., Ltd. Oral disintegrating tablet
CA2687813C (en) * 2007-05-22 2015-07-07 Ssci, Inc. Preparation of mannitol modification iii
DE102007052070A1 (de) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Candesartancilexetil
US8716536B2 (en) 2010-12-17 2014-05-06 Merck Patent Gmbh Process for the preparation of directly compressible δ-mannitol
EP2764045B1 (en) 2011-10-05 2017-03-01 FMC Corporation Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
CN103842425B (zh) 2011-10-05 2017-05-24 Fmc有限公司 微晶纤维素和羧甲基纤维素的稳定剂组合物、制备方法和应用
CN104010522A (zh) 2011-12-09 2014-08-27 Fmc有限公司 共磨碎稳定剂组合物
MX2017000827A (es) * 2014-07-21 2017-05-01 Roquette Freres Composiciones de azucar para la formacion de comprimidos por compresion directa.
IT201900002857A1 (it) 2019-02-27 2020-08-27 Ntc S R L Procedimento di riempimento di contenitori con una polvere
CN113116843A (zh) * 2021-05-11 2021-07-16 福建海西新药创制有限公司 一种含有缬沙坦的药物组合物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
DE3245170A1 (de) 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
FR2571046B1 (fr) 1984-10-03 1987-10-16 Roquette Freres Procede de preparation de mannitol granulaire directement compressible
FR2571045B1 (fr) 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
JPH0653658B2 (ja) 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
NO177005C (no) 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
DE69022861T2 (de) 1989-01-24 1996-04-04 Spi Polyols Inc Kryoschützende kristalline Sorbitolkügelchen.
DK0390435T3 (da) 1989-03-29 1994-03-21 Takeda Chemical Industries Ltd Blanding indeholdende en forbindelse fra vitamin B gruppen, og fremstilling deraf
US5177080A (en) 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
HU217629B (hu) * 1991-12-12 2000-03-28 Novartis Ag. Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
AUPM411494A0 (en) 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation

Also Published As

Publication number Publication date
TW515787B (en) 2003-01-01
TR199802079T2 (xx) 1999-02-22
NO984803D0 (no) 1998-10-15
ES2158540T5 (es) 2004-11-16
ID16566A (id) 1997-10-16
IL126580A0 (en) 1999-08-17
CZ333698A3 (cs) 1999-01-13
IL126580A (en) 2001-08-08
US20020107420A1 (en) 2002-08-08
BG63460B1 (bg) 2002-02-28
EA000968B1 (ru) 2000-08-28
US6503918B2 (en) 2003-01-07
CN1221398A (zh) 1999-06-30
BR9708672A (pt) 1999-08-03
DE69705516D1 (de) 2001-08-09
ATE202768T1 (de) 2001-07-15
PT902777E (pt) 2001-11-30
DE69705516T2 (de) 2002-04-25
EP0902777B1 (en) 2001-07-04
PL329614A1 (en) 1999-03-29
DE69705516T3 (de) 2004-09-30
HUP9902165A2 (hu) 1999-11-29
NO311349B1 (no) 2001-11-19
SK282768B6 (sk) 2002-12-03
NO20012249D0 (no) 2001-05-07
CA2251092A1 (en) 1997-10-23
EA199800888A1 (ru) 1999-04-29
DK0902777T3 (da) 2001-09-24
GR3036760T3 (en) 2001-12-31
NO20012249L (no) 1998-12-16
WO1997038960A1 (en) 1997-10-23
ES2158540T3 (es) 2001-09-01
KR20000005486A (ko) 2000-01-25
AU718658B2 (en) 2000-04-20
AU2522297A (en) 1997-11-07
HUP9902165A3 (en) 2001-01-29
NO984803L (no) 1998-12-16
EP0902777A1 (en) 1999-03-24
DK0902777T4 (da) 2004-10-11
BG102818A (en) 1999-05-31
NZ332313A (en) 2000-02-28
EP0902777B2 (en) 2004-06-16
SK143298A3 (en) 1999-04-13

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