CU20150037A7 - Soluciones inyectables estables exentas de conservantes de compuestos antimidriásicos y anti-inflamatorios - Google Patents
Soluciones inyectables estables exentas de conservantes de compuestos antimidriásicos y anti-inflamatoriosInfo
- Publication number
- CU20150037A7 CU20150037A7 CUP2015000037A CU20150037A CU20150037A7 CU 20150037 A7 CU20150037 A7 CU 20150037A7 CU P2015000037 A CUP2015000037 A CU P2015000037A CU 20150037 A CU20150037 A CU 20150037A CU 20150037 A7 CU20150037 A7 CU 20150037A7
- Authority
- CU
- Cuba
- Prior art keywords
- antimidriassic
- preservants
- exempt
- injectable solutions
- inflammatory compounds
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 abstract 1
- 229960004752 ketorolac Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 abstract 1
- 229960001802 phenylephrine Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/08—Mydriatics or cycloplegics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Rheumatology (AREA)
- Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261718026P | 2012-10-24 | 2012-10-24 | |
| US201261736179P | 2012-12-12 | 2012-12-12 | |
| PCT/US2013/066349 WO2014066485A1 (en) | 2012-10-24 | 2013-10-23 | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20150037A7 true CU20150037A7 (es) | 2015-08-27 |
Family
ID=50545210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2015000037A CU20150037A7 (es) | 2012-10-24 | 2015-04-21 | Soluciones inyectables estables exentas de conservantes de compuestos antimidriásicos y anti-inflamatorios |
Country Status (39)
Families Citing this family (24)
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| WO2004010894A2 (en) | 2002-07-30 | 2004-02-05 | Omeros Corporation | Ophthalmologic irrigation solutions and method |
| AU2013201465B2 (en) * | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| US20210346318A1 (en) * | 2013-10-03 | 2021-11-11 | Harrow Ip, Llc | Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof |
| JP2016532723A (ja) | 2013-10-03 | 2016-10-20 | インプリミス・ファーマシューティカルズ・インコーポレイテッドＩｍｐｒｉｍｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 眼内投与のためのエピネフリン系点眼用組成物及びその製造のための方法 |
| TWI809304B (zh) * | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| CN104856990A (zh) * | 2015-05-07 | 2015-08-26 | 武汉武药科技有限公司 | 去氧肾上腺素酮咯酸溶液及制备方法 |
| US11213480B1 (en) | 2015-08-06 | 2022-01-04 | Hikma Pharmaceuticals International Limited | Phenylephrine hydrochloride ready-to-use solution |
| USD831868S1 (en) | 2015-09-17 | 2018-10-23 | Lume Cube, Inc. | Compact external light |
| US10704745B2 (en) | 2015-10-13 | 2020-07-07 | Lume Cube, Inc. | Mobile light source |
| JP2019524896A (ja) | 2016-08-25 | 2019-09-05 | ハーロウ・ヘルス・インコーポレイテッドＨａｒｒｏｗ Ｈｅａｌｔｈ， Ｉｎｃ． | 眼内投与のためのエピネフリンベースの眼科組成物及びその製造方法 |
| US20180318319A1 (en) * | 2017-05-04 | 2018-11-08 | Ocular Science, Inc. | Compositions and Methods for Treating Eyes and Methods of Preparation |
| JP7078843B2 (ja) * | 2018-03-26 | 2022-06-01 | サミー株式会社 | 遊技機 |
| KR20210096096A (ko) * | 2018-10-26 | 2021-08-04 | 오큐파이어 파마, 인크. | 노안, 산동, 및 기타 안구 장애의 치료를 위한 방법 및 조성물 |
| US11071724B2 (en) | 2019-05-17 | 2021-07-27 | Ocular Science, Inc. | Compositions and methods for treating presbyopia |
| DE102019125430B3 (de) | 2019-09-20 | 2020-11-19 | Carl Zeiss Meditec Ag | Steuerungsvorrichtung für ein ophthalmochirurgisches System, ophthalmochirurgisches System sowie Computerprogrammprodukt |
| KR102749980B1 (ko) | 2020-01-02 | 2025-01-03 | 삼성전자주식회사 | 에어 스페이서를 가지는 반도체 소자 |
| US20210228507A1 (en) * | 2020-01-22 | 2021-07-29 | Nevakar Inc. | Phenylephrine Hydrochloride Compositions and Containers |
| WO2022132567A1 (en) * | 2020-12-17 | 2022-06-23 | Harrow Ip, Llc | Mydriatic compositions and methods for fabricating thereof |
| CN115368310B (zh) | 2021-05-18 | 2025-06-27 | 奥库菲尔医药公司 | 合成甲磺酸酚妥拉明的方法 |
| US11793789B2 (en) | 2021-07-23 | 2023-10-24 | Somerset Therapeutics, Llc | Treatment of ophthalmological conditions using buffer-free ophthalmological compositions of ketorolac and phenylephrine |
| US12029729B2 (en) | 2021-07-23 | 2024-07-09 | Somerset Therapeutics, Llc | Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof |
| WO2024086268A1 (en) * | 2022-10-19 | 2024-04-25 | Fresenius Kabi Austria Gmbh | Phenylephrine liquid formulations |
| CN115950992B (zh) * | 2023-03-15 | 2023-06-09 | 苏州朗易生物医药研究有限公司 | 一种去氧肾上腺素酮咯酸溶液中有关物质的检测方法及其应用 |
| WO2025165753A1 (en) * | 2024-01-31 | 2025-08-07 | Hikma Pharmaceuticals Usa Inc. | Pharmaceutical formulations of phenylephrine and process of making the same |
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