BR112015014078A2 - composição farmacêutica oftalmológica tópica que contém regorefenib - Google Patents

composição farmacêutica oftalmológica tópica que contém regorefenib

Info

Publication number
BR112015014078A2
BR112015014078A2 BR112015014078A BR112015014078A BR112015014078A2 BR 112015014078 A2 BR112015014078 A2 BR 112015014078A2 BR 112015014078 A BR112015014078 A BR 112015014078A BR 112015014078 A BR112015014078 A BR 112015014078A BR 112015014078 A2 BR112015014078 A2 BR 112015014078A2
Authority
BR
Brazil
Prior art keywords
regorefenib
pharmaceutical composition
composition containing
topical ophthalmic
ophthalmic pharmaceutical
Prior art date
Application number
BR112015014078A
Other languages
English (en)
Inventor
Ohm Andreas
Richter Annett
Riedl Bernd
Hirth-Dietrich Claudia
Von Degenfeld Georges
Keldenich Joerg
Freundlieb Julia
Klar Jürgen
Böttger Michael
Muenster Uwe
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of BR112015014078A2 publication Critical patent/BR112015014078A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
BR112015014078A 2012-12-21 2013-12-21 composição farmacêutica oftalmológica tópica que contém regorefenib BR112015014078A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12198892 2012-12-21
PCT/US2013/077358 WO2014100797A1 (en) 2012-12-21 2013-12-21 Topical ophthalmological pharmaceutical composition containing regorafenib

Publications (1)

Publication Number Publication Date
BR112015014078A2 true BR112015014078A2 (pt) 2018-05-15

Family

ID=47458742

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015014078A BR112015014078A2 (pt) 2012-12-21 2013-12-21 composição farmacêutica oftalmológica tópica que contém regorefenib

Country Status (27)

Country Link
US (2) US20140179745A1 (pt)
EP (1) EP2934481A1 (pt)
JP (1) JP2016507505A (pt)
KR (1) KR20150100670A (pt)
CN (1) CN104955443A (pt)
AP (1) AP2015008493A0 (pt)
AR (1) AR094104A1 (pt)
AU (1) AU2013364004A1 (pt)
BR (1) BR112015014078A2 (pt)
CA (1) CA2895804A1 (pt)
CL (1) CL2015001701A1 (pt)
CR (1) CR20150327A (pt)
CU (1) CU20150063A7 (pt)
DO (1) DOP2015000155A (pt)
EA (1) EA201500669A1 (pt)
EC (1) ECSP15026386A (pt)
IL (1) IL238791A0 (pt)
MA (1) MA38215A1 (pt)
MX (1) MX2015007488A (pt)
PE (1) PE20151784A1 (pt)
PH (1) PH12015501407A1 (pt)
SG (1) SG11201503838WA (pt)
TN (1) TN2015000280A1 (pt)
TW (1) TW201431568A (pt)
UY (1) UY35183A (pt)
WO (1) WO2014100797A1 (pt)
ZA (1) ZA201505196B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017197509A1 (en) * 2016-05-16 2017-11-23 Joseph Gabriele Transdermal formulations for delivery of celecoxib and its use in the treatment of celecoxib-responsive diseases and conditions
CN112834485B (zh) * 2021-02-07 2022-03-29 西南交通大学 激光诱导击穿光谱元素定量分析的一种非定标方法
KR102413226B1 (ko) 2021-08-26 2022-06-23 충북대학교 산학협력단 레고라페닙을 유효성분으로 포함하는 항노화 조성물
KR20230166353A (ko) 2022-05-30 2023-12-07 (주) 레비레스코 감태 추출물, 귤피 추출물, 및 녹차 추출물을 유효성분으로 포함하는 자외선에 대한 세포 보호용 또는 mmp-1 발현 억제용 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA84156C2 (ru) 2003-07-23 2008-09-25 Байер Фармасьютикалс Корпорейшн Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний
CN101175475B (zh) 2005-05-10 2010-04-14 爱尔康公司 包含活性成分、泊洛沙姆或美洛沙泊表面活性剂和二醇的混悬制剂、其用于生产治疗眼科病症的药物的用途
NZ563984A (en) 2005-06-08 2011-11-25 Targegen Inc Methods and compositions for the treatment of ocular disorders
MX2008006379A (es) 2005-11-29 2009-03-03 Smithkline Beecham Corp Metodo de tratamiento.
EP1962828A1 (en) * 2005-12-15 2008-09-03 Bayer HealthCare AG Diaryl urea for treating inflammatory skin, eye and/or ear diseases
US20070149593A1 (en) 2005-12-23 2007-06-28 Alcon, Inc. PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE
WO2008027341A2 (en) 2006-08-30 2008-03-06 Merck & Co., Inc. Topical ophthalmic formulations
AR062927A1 (es) 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
CA2760687A1 (en) 2009-05-01 2010-11-04 Ophthotech Corporation Methods for treating or preventing ophthalmological diseases
WO2011009016A1 (en) 2009-07-16 2011-01-20 Glaxo Wellcome Manufacturing Pte Ltd Treatment method
WO2013000917A1 (en) * 2011-06-28 2013-01-03 Bayer Intellectual Property Gmbh Topical ophthalmological pharmaceutical composition containing regorafenib

Also Published As

Publication number Publication date
CR20150327A (es) 2015-09-14
AR094104A1 (es) 2015-07-08
AU2013364004A1 (en) 2015-06-04
AP2015008493A0 (en) 2015-05-31
IL238791A0 (en) 2015-06-30
US20150328145A1 (en) 2015-11-19
JP2016507505A (ja) 2016-03-10
CL2015001701A1 (es) 2015-10-16
CU20150063A7 (es) 2015-11-27
DOP2015000155A (es) 2015-08-31
ZA201505196B (en) 2017-11-29
MA38215A1 (fr) 2017-01-31
TW201431568A (zh) 2014-08-16
EA201500669A1 (ru) 2015-12-30
EP2934481A1 (en) 2015-10-28
SG11201503838WA (en) 2015-07-30
KR20150100670A (ko) 2015-09-02
TN2015000280A1 (en) 2016-10-03
WO2014100797A1 (en) 2014-06-26
CN104955443A (zh) 2015-09-30
PH12015501407A1 (en) 2015-09-07
PE20151784A1 (es) 2015-11-25
MX2015007488A (es) 2015-09-04
CA2895804A1 (en) 2014-06-26
UY35183A (es) 2014-07-31
ECSP15026386A (es) 2016-01-29
US20140179745A1 (en) 2014-06-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2472 DE 22-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.