CS76792A3 - Process of diastereo selective reductive pinalcol coupling of homochiralalpha-amino aldehydes - Google Patents
Process of diastereo selective reductive pinalcol coupling of homochiralalpha-amino aldehydes Download PDFInfo
- Publication number
- CS76792A3 CS76792A3 CS92767A CS76792A CS76792A3 CS 76792 A3 CS76792 A3 CS 76792A3 CS 92767 A CS92767 A CS 92767A CS 76792 A CS76792 A CS 76792A CS 76792 A3 CS76792 A3 CS 76792A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- alkyl
- formula
- amino
- hydrogen
- alkylamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Lubricants (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4108357 | 1991-03-15 | ||
| DE4122911A DE4122911A1 (de) | 1991-07-11 | 1991-07-11 | Verfahren zur diastereoselektiven reduktiven pinakol-kupplung von homochiralen (alpha)-aminoaldehyden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS76792A3 true CS76792A3 (en) | 1992-10-14 |
Family
ID=25901877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS92767A CS76792A3 (en) | 1991-03-15 | 1992-03-13 | Process of diastereo selective reductive pinalcol coupling of homochiralalpha-amino aldehydes |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5519113A (fi) |
| EP (1) | EP0503561B1 (fi) |
| JP (1) | JP3254238B2 (fi) |
| KR (1) | KR920018013A (fi) |
| AT (1) | ATE172713T1 (fi) |
| AU (1) | AU664696B2 (fi) |
| CA (1) | CA2063013A1 (fi) |
| CS (1) | CS76792A3 (fi) |
| DE (1) | DE59209540D1 (fi) |
| DK (1) | DK0503561T3 (fi) |
| ES (1) | ES2124710T3 (fi) |
| FI (1) | FI921069L (fi) |
| HU (1) | HUT62851A (fi) |
| IE (1) | IE920828A1 (fi) |
| MX (1) | MX9201116A (fi) |
| NO (1) | NO920984L (fi) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362912A (en) * | 1989-05-23 | 1994-11-08 | Abbott Laboratories | Process for the preparation of a substituted diaminodiol |
| EP2261232A3 (en) * | 1998-03-19 | 2011-04-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of caspases |
| PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| WO2003068242A1 (en) * | 2002-02-11 | 2003-08-21 | Vertex Pharmaceuticals Incorporated | Phospholipids as caspase inhibitor prodrugs |
| JP2008500374A (ja) * | 2004-05-27 | 2008-01-10 | バーテックス ファーマシューティカルズ インコーポレイテッド | 自己炎症性疾患の処置のためのｉｃｅインヒビター |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| FI925441A7 (fi) * | 1990-06-01 | 1992-11-30 | The Du Pont Merck Pharmaceutical Company | 1,4-diamino-2,3-dihydroksibutaaneja |
| EP0665215A1 (en) * | 1990-06-01 | 1995-08-02 | The Du Pont Merck Pharmaceutical Company | 1,4-Diamino-2,3-dihydroxybutanes |
-
1992
- 1992-03-10 DE DE59209540T patent/DE59209540D1/de not_active Expired - Fee Related
- 1992-03-10 ES ES92104085T patent/ES2124710T3/es not_active Expired - Lifetime
- 1992-03-10 DK DK92104085T patent/DK0503561T3/da active
- 1992-03-10 EP EP92104085A patent/EP0503561B1/de not_active Expired - Lifetime
- 1992-03-10 AT AT92104085T patent/ATE172713T1/de not_active IP Right Cessation
- 1992-03-12 FI FI921069A patent/FI921069L/fi unknown
- 1992-03-13 IE IE082892A patent/IE920828A1/en unknown
- 1992-03-13 JP JP05511292A patent/JP3254238B2/ja not_active Expired - Fee Related
- 1992-03-13 CS CS92767A patent/CS76792A3/cs unknown
- 1992-03-13 CA CA002063013A patent/CA2063013A1/en not_active Abandoned
- 1992-03-13 MX MX9201116A patent/MX9201116A/es not_active IP Right Cessation
- 1992-03-13 NO NO92920984A patent/NO920984L/no unknown
- 1992-03-13 HU HU9200864A patent/HUT62851A/hu unknown
- 1992-03-13 AU AU12840/92A patent/AU664696B2/en not_active Ceased
- 1992-03-14 KR KR1019920004188A patent/KR920018013A/ko not_active Withdrawn
-
1994
- 1994-06-13 US US08/259,135 patent/US5519113A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0503561B1 (de) | 1998-10-28 |
| AU1284092A (en) | 1992-09-17 |
| CA2063013A1 (en) | 1992-09-16 |
| AU664696B2 (en) | 1995-11-30 |
| JPH0578290A (ja) | 1993-03-30 |
| US5519113A (en) | 1996-05-21 |
| ES2124710T3 (es) | 1999-02-16 |
| EP0503561A3 (en) | 1993-05-05 |
| FI921069A0 (fi) | 1992-03-12 |
| MX9201116A (es) | 1992-10-01 |
| ATE172713T1 (de) | 1998-11-15 |
| HUT62851A (en) | 1993-06-28 |
| EP0503561A2 (de) | 1992-09-16 |
| HU9200864D0 (en) | 1992-05-28 |
| DK0503561T3 (da) | 1999-07-05 |
| JP3254238B2 (ja) | 2002-02-04 |
| NO920984L (no) | 1992-09-16 |
| NO920984D0 (no) | 1992-03-13 |
| KR920018013A (ko) | 1992-10-21 |
| DE59209540D1 (de) | 1998-12-03 |
| FI921069A7 (fi) | 1992-09-16 |
| IE920828A1 (en) | 1992-09-23 |
| FI921069L (fi) | 1992-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5498728A (en) | Derivatives of L-tryptophanal and their use as medicinals | |
| CA2026382A1 (en) | Inhibitors of retroviral proteases | |
| CA2022692A1 (en) | Renin inhibitors | |
| IE54291B1 (en) | 2-azaspiro(4.(3+n))-3-carboxylic acid derivatives, a process for their preparation, agents containing these derivatives and their use | |
| PH26816A (en) | Diol-containing renin inhibitors | |
| CZ127694A3 (en) | Novel derivatives of amino acids, process of their preparation and pharmaceutical preparations in which they are comprised | |
| PT91426A (pt) | Processo para a preparacao de composicoes farmaceuticas antiviricas incorporando derivados de acido alfa-aminoboronico | |
| NZ206733A (en) | Disubstituted proline derivatives, their preparation and intermediates | |
| US5463124A (en) | Process for the diastereoselective reductive pinacol coupling of homochiral α-aminoaldehydes | |
| CS76792A3 (en) | Process of diastereo selective reductive pinalcol coupling of homochiralalpha-amino aldehydes | |
| CN114456101A (zh) | 用于合成pf-07321332的关键中间体的合成方法 | |
| FI95272B (fi) | Menetelmä terapeuttisesti käyttökelpoisen sykloheksyylidifluoroepeptidin valmistamiseksi | |
| IE49123B1 (en) | (1,4)thiazines or thiazepines | |
| CN118613490A (zh) | 大环免疫调节剂 | |
| JPH0570495A (ja) | 環式ヘキサペプチド化合物 | |
| IL118869A (en) | Antimicrobial mixtures containing a - amino acids and cyclopentane - b - amino acids and pharmaceutical preparations containing them | |
| OA11325A (en) | Process for preparing growth hormone secretagogues. | |
| Paquet et al. | Further studies on the synthesis of symmetrical anhydrides and 2, 4-disubstituted-5 (4 H)-oxazolones from N-alkoxycarbonylamino acids using soluble carbodiimide | |
| IE66524B1 (en) | A process for the preparation of peptides by solid-phase synthesis | |
| DE4039569A1 (de) | Inhibitoren retroviraler proteasen | |
| US3124564A (en) | Peptide synthesis with acylamino acids- | |
| DE4030350A1 (de) | Inhibitoren retroviraler proteasen | |
| GB2196958A (en) | Halo-homostatin peptide derivatives, their preparation and pharmaceutical compositions containing them | |
| DE4122885A1 (de) | Verfahren zur diastereoselektiven reduktiven pinakol-kupplung von homochiralen (alpha)-aminoaldehyden | |
| TWI276626B (en) | Process for preparing of 3,4-dehydroprolines or 3,4-dehydropiperidines |