CS70891A2 - Substituted purines, method of their production and their application as antiviral agents - Google Patents

Substituted purines, method of their production and their application as antiviral agents

Info

Publication number
CS70891A2
CS70891A2 CS91708A CS70891A CS70891A2 CS 70891 A2 CS70891 A2 CS 70891A2 CS 91708 A CS91708 A CS 91708A CS 70891 A CS70891 A CS 70891A CS 70891 A2 CS70891 A2 CS 70891A2
Authority
CS
Czechoslovakia
Prior art keywords
ch2ph
alkyl
dialkylamino
production
application
Prior art date
Application number
CS91708A
Other languages
Czech (cs)
English (en)
Inventor
Gerhard Dr Jahne
Manfred Dr Rosner
Irvin Dr Winkler
Matthias Dr Helsberg
Thomas Dr Scholl
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS70891A2 publication Critical patent/CS70891A2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS91708A 1990-03-20 1991-03-18 Substituted purines, method of their production and their application as antiviral agents CS70891A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4008858A DE4008858A1 (de) 1990-03-20 1990-03-20 Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel

Publications (1)

Publication Number Publication Date
CS70891A2 true CS70891A2 (en) 1991-11-12

Family

ID=6402601

Family Applications (1)

Application Number Title Priority Date Filing Date
CS91708A CS70891A2 (en) 1990-03-20 1991-03-18 Substituted purines, method of their production and their application as antiviral agents

Country Status (19)

Country Link
EP (1) EP0452680B1 (ja)
JP (1) JP3146423B2 (ja)
KR (1) KR910016751A (ja)
CN (1) CN1054982A (ja)
AT (1) ATE144984T1 (ja)
AU (1) AU644414B2 (ja)
CA (1) CA2038589A1 (ja)
CS (1) CS70891A2 (ja)
DE (2) DE4008858A1 (ja)
DK (1) DK0452680T3 (ja)
ES (1) ES2093651T3 (ja)
FI (1) FI911310A (ja)
GR (1) GR3021591T3 (ja)
HU (1) HUT57764A (ja)
IE (1) IE910908A1 (ja)
IL (1) IL97586A0 (ja)
NO (1) NO911081L (ja)
PT (1) PT97080A (ja)
ZA (1) ZA912015B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4210221A1 (de) * 1992-03-28 1993-09-30 Hoechst Ag Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung
DE59310344D1 (de) * 1992-09-24 2003-07-24 Hoechst Ag N1-Substituierte 1H-1,2,3-Triazolo[4,5-d]pyrimidine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als antivirale Mittel
DE4311801A1 (de) * 1993-04-09 1994-10-13 Hoechst Ag Neue Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
US5891881A (en) * 1997-11-21 1999-04-06 Clarion Pharmaceuticals Inc. Aminoheterocycle-substituted glycerols
FR2793794B1 (fr) * 1999-05-21 2001-07-27 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
PE20030008A1 (es) 2001-06-19 2003-01-22 Bristol Myers Squibb Co Inhibidores duales de pde 7 y pde 4

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides

Also Published As

Publication number Publication date
PT97080A (pt) 1991-11-29
JPH04217984A (ja) 1992-08-07
AU7351491A (en) 1991-09-26
ATE144984T1 (de) 1996-11-15
KR910016751A (ko) 1991-11-05
FI911310A0 (fi) 1991-03-18
IL97586A0 (en) 1992-06-21
EP0452680B1 (de) 1996-11-06
CA2038589A1 (en) 1991-09-21
NO911081D0 (no) 1991-03-19
CN1054982A (zh) 1991-10-02
JP3146423B2 (ja) 2001-03-19
HUT57764A (en) 1991-12-30
NO911081L (no) 1991-09-23
EP0452680A1 (de) 1991-10-23
AU644414B2 (en) 1993-12-09
GR3021591T3 (en) 1997-02-28
ES2093651T3 (es) 1997-01-01
FI911310A (fi) 1991-09-21
DE59108319D1 (de) 1996-12-12
IE910908A1 (en) 1991-09-25
DE4008858A1 (de) 1991-09-26
ZA912015B (en) 1991-12-24
HU910928D0 (en) 1991-10-28
DK0452680T3 (da) 1997-04-07

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