CS573586A2 - Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction - Google Patents

Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction

Info

Publication number
CS573586A2
CS573586A2 CS865735A CS573586A CS573586A2 CS 573586 A2 CS573586 A2 CS 573586A2 CS 865735 A CS865735 A CS 865735A CS 573586 A CS573586 A CS 573586A CS 573586 A2 CS573586 A2 CS 573586A2
Authority
CS
Czechoslovakia
Prior art keywords
phenosypropylamine
ethoxyphenolh
derivativesprodduction
hydroxy
Prior art date
Application number
CS865735A
Other languages
English (en)
Other versions
CS266593B2 (en
Inventor
Brian R Holloway
Ralph Howe
Balbir Singh Rao
Donald Stribling
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of CS573586A2 publication Critical patent/CS573586A2/cs
Publication of CS266593B2 publication Critical patent/CS266593B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
CS865735A 1985-07-30 1986-07-30 Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction CS266593B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858519154A GB8519154D0 (en) 1985-07-30 1985-07-30 Aromatic ethers

Publications (2)

Publication Number Publication Date
CS573586A2 true CS573586A2 (en) 1989-04-14
CS266593B2 CS266593B2 (en) 1990-01-12

Family

ID=10583042

Family Applications (1)

Application Number Title Priority Date Filing Date
CS865735A CS266593B2 (en) 1985-07-30 1986-07-30 Method of 2-(2-hydroxy-3-phenosypropylamine) ethoxyphenolh's derivativesprodduction

Country Status (27)

Country Link
US (1) US4772631A (cs)
EP (1) EP0210849B1 (cs)
JP (2) JPH0651661B2 (cs)
KR (1) KR870001142A (cs)
CN (1) CN1014516B (cs)
AR (1) AR242176A1 (cs)
AT (1) ATE55980T1 (cs)
AU (1) AU603987B2 (cs)
CA (1) CA1283122C (cs)
CS (1) CS266593B2 (cs)
DD (1) DD251551A5 (cs)
DE (1) DE3673722D1 (cs)
DK (1) DK168761B1 (cs)
ES (1) ES2002720A6 (cs)
FI (1) FI88030C (cs)
GB (1) GB8519154D0 (cs)
GR (1) GR861994B (cs)
HU (1) HUT44757A (cs)
IE (1) IE60157B1 (cs)
IL (1) IL79447A0 (cs)
NO (1) NO170480C (cs)
NZ (1) NZ217011A (cs)
PH (1) PH22503A (cs)
PL (1) PL152320B1 (cs)
PT (1) PT83085B (cs)
SU (1) SU1632370A3 (cs)
ZA (1) ZA865097B (cs)

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DE3866984D1 (en) * 1987-07-21 1992-01-30 Hoffmann La Roche Phenoxypropanolamine.
GB8801306D0 (en) * 1988-01-21 1988-02-17 Ici Plc Chemical compounds
GB8905336D0 (en) * 1989-03-08 1989-04-19 Ici Plc Chemical compounds
GB8910374D0 (en) * 1989-05-05 1989-06-21 Ici Plc Chemical compounds
KR920005952B1 (ko) * 1989-05-26 1992-07-25 이사무 이와이 오수정화조의 여과재 순환 정화장치
GB8925032D0 (en) * 1989-11-06 1989-12-28 Ici Plc Chemical compounds
GB8926083D0 (en) * 1989-11-17 1990-01-10 Ici Plc Therapeutic agents
GB9003185D0 (en) * 1990-02-13 1990-04-11 Ici Plc Pharmaceutical compositions
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
US5151439A (en) * 1990-05-04 1992-09-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5245053A (en) * 1990-05-04 1993-09-14 American Cyanamid Company Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles
GB9016655D0 (en) * 1990-07-30 1990-09-12 Ici Plc Therapeutic agents
GB9111425D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
GB9111426D0 (en) 1991-05-28 1991-07-17 Ici Plc Chemical compounds
GB9224740D0 (en) * 1992-11-26 1993-01-13 Ici Plc Therapeutic agents
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5488064A (en) * 1994-05-02 1996-01-30 Bristol-Myers Squibb Company Benzo 1,3 dioxole derivatives
US5491134A (en) * 1994-09-16 1996-02-13 Bristol-Myers Squibb Company Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6075040A (en) * 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
ES2171839T3 (es) 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
GB9812709D0 (en) * 1998-06-13 1998-08-12 Glaxo Group Ltd Chemical compounds
US6344481B1 (en) 1999-03-01 2002-02-05 Pfizer Inc. Thyromimetic antiobesity agents
US7504435B2 (en) * 2001-01-31 2009-03-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for stimulating weight loss and/or for lowering triglycerides in patients
US7709677B2 (en) * 2001-01-31 2010-05-04 Glaxosmithkline Llc Process of preparing arylethanoldiamines
GB0102407D0 (en) 2001-01-31 2001-03-14 Glaxo Group Ltd Process
US7202222B2 (en) * 2003-01-06 2007-04-10 National Bioscience Corporation Methods for treatment of obesity and effective fat loss promotion
MX2009009171A (es) * 2007-02-27 2010-03-04 Univ Arizona State Administracion de acido 3,5-diyodotiropropionico para estimular perdida de peso y/o disminuir niveles de trigliceridos y/o para tratar sindrome metabolico.
US8476227B2 (en) 2010-01-22 2013-07-02 Ethicon Endo-Surgery, Inc. Methods of activating a melanocortin-4 receptor pathway in obese subjects
US9044606B2 (en) 2010-01-22 2015-06-02 Ethicon Endo-Surgery, Inc. Methods and devices for activating brown adipose tissue using electrical energy
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
US9522129B2 (en) 2010-08-03 2016-12-20 Velicept Therapeutics, Inc. Pharmaceutical Combination
EP2819993B1 (en) * 2012-03-01 2020-09-02 University Of Cincinnati Ros-activated compounds as selective anti-cancer therapeutics
CA2969405A1 (en) 2014-12-03 2016-06-09 Velicept Therapeutics, Inc. Compositions and methods of using modified release solabegron for lower urinary tract symptoms
US10092738B2 (en) 2014-12-29 2018-10-09 Ethicon Llc Methods and devices for inhibiting nerves when activating brown adipose tissue
US10080884B2 (en) 2014-12-29 2018-09-25 Ethicon Llc Methods and devices for activating brown adipose tissue using electrical energy
WO2017070689A2 (en) 2015-10-23 2017-04-27 Velicept Therapeutics, Inc. Solabegron zwitterion and uses thereof

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GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
BE741762A (cs) * 1968-11-18 1970-05-19
SE354851B (cs) * 1970-02-18 1973-03-26 Haessle Ab
US4146638A (en) * 1976-02-17 1979-03-27 Boehringer Ingelheim Gmbh N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
SE416545B (sv) * 1976-10-07 1981-01-19 Haessle Ab Forfarande for framstellning av nya hjertaktiva 1-frnoxi-3-aminopropan-2-ol-derivat
CH632987A5 (en) * 1976-10-07 1982-11-15 Haessle Ab Process for preparing novel amines
EP0006735B1 (en) * 1978-06-28 1983-06-15 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
SE7807408L (sv) * 1978-06-30 1979-12-31 Haessle Ab Hjertaktiva foreningar
ATE1994T1 (de) * 1979-06-16 1982-12-15 Beecham Group Plc Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
ATE2265T1 (de) * 1979-10-25 1983-02-15 Beecham Group Plc Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
IL65541A0 (en) * 1981-05-06 1982-07-30 Haessle Ab Alkylamino-2-propanols,process for their preparation and pharmaceutical preparations containing same
GB8415377D0 (en) * 1984-06-15 1984-07-18 Beecham Group Plc Compounds
GB8510146D0 (en) * 1985-04-20 1985-05-30 Smith Kline French Lab Chemical compounds & processes

Also Published As

Publication number Publication date
FI862896A0 (fi) 1986-07-09
CN86105400A (zh) 1987-03-11
PH22503A (en) 1988-09-12
DK168761B1 (da) 1994-06-06
PT83085A (en) 1986-08-01
SU1632370A3 (ru) 1991-02-28
JPH0819062B2 (ja) 1996-02-28
JPS6277357A (ja) 1987-04-09
JPH06340597A (ja) 1994-12-13
DK359986D0 (da) 1986-07-29
NO170480C (no) 1992-10-21
NO170480B (no) 1992-07-13
ES2002720A6 (es) 1988-10-01
NO863061D0 (no) 1986-07-29
CS266593B2 (en) 1990-01-12
IE60157B1 (en) 1994-06-15
ATE55980T1 (de) 1990-09-15
IE861827L (en) 1987-01-30
GB8519154D0 (en) 1985-09-04
CA1283122C (en) 1991-04-16
GR861994B (en) 1986-11-26
EP0210849A1 (en) 1987-02-04
JPH0651661B2 (ja) 1994-07-06
HUT44757A (en) 1988-04-28
PL260759A1 (en) 1988-09-15
NO863061L (no) 1987-02-02
NZ217011A (en) 1990-02-26
ZA865097B (en) 1987-03-25
FI862896L (fi) 1987-01-31
FI88030C (fi) 1993-03-25
AU6002986A (en) 1987-02-05
US4772631A (en) 1988-09-20
EP0210849B1 (en) 1990-08-29
AU603987B2 (en) 1990-12-06
AR242176A1 (es) 1993-03-31
KR870001142A (ko) 1987-03-11
IL79447A0 (en) 1986-10-31
DD251551A5 (de) 1987-11-18
PT83085B (pt) 1989-01-30
DK359986A (da) 1987-01-31
DE3673722D1 (en) 1990-10-04
CN1014516B (zh) 1991-10-30
FI88030B (fi) 1992-12-15
PL152320B1 (en) 1990-12-31

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