CS323091A3 - 8-azabicyclo /3.2.1/octylalkylthiazolidinones, process of their preparation and their application as medicaments - Google Patents

8-azabicyclo /3.2.1/octylalkylthiazolidinones, process of their preparation and their application as medicaments Download PDF

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Publication number
CS323091A3
CS323091A3 CS913230A CS323091A CS323091A3 CS 323091 A3 CS323091 A3 CS 323091A3 CS 913230 A CS913230 A CS 913230A CS 323091 A CS323091 A CS 323091A CS 323091 A3 CS323091 A3 CS 323091A3
Authority
CS
Czechoslovakia
Prior art keywords
azabicyclo
compound
formula
independently hydrogen
thiazolidinone
Prior art date
Application number
CS913230A
Other languages
Czech (cs)
English (en)
Inventor
Nicholas J Hrib
John G Jurcak
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of CS323091A3 publication Critical patent/CS323091A3/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS913230A 1990-10-26 1991-10-24 8-azabicyclo /3.2.1/octylalkylthiazolidinones, process of their preparation and their application as medicaments CS323091A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/603,491 US5045546A (en) 1990-10-26 1990-10-26 8-azabicyclo[3.2.1]octylalkylthiazolidines

Publications (1)

Publication Number Publication Date
CS323091A3 true CS323091A3 (en) 1992-05-13

Family

ID=24415671

Family Applications (1)

Application Number Title Priority Date Filing Date
CS913230A CS323091A3 (en) 1990-10-26 1991-10-24 8-azabicyclo /3.2.1/octylalkylthiazolidinones, process of their preparation and their application as medicaments

Country Status (19)

Country Link
US (1) US5045546A (ja)
EP (1) EP0483633B1 (ja)
JP (1) JP2564719B2 (ja)
AT (1) ATE151422T1 (ja)
AU (1) AU639195B2 (ja)
BR (1) BR9104632A (ja)
CA (1) CA2054225A1 (ja)
CS (1) CS323091A3 (ja)
DE (1) DE69125569T2 (ja)
DK (1) DK0483633T3 (ja)
ES (1) ES2099727T3 (ja)
FI (1) FI915025A (ja)
GR (1) GR3023441T3 (ja)
HU (1) HUT59401A (ja)
IE (1) IE913756A1 (ja)
NO (1) NO914192L (ja)
PT (1) PT99331B (ja)
YU (1) YU168491A (ja)
ZA (1) ZA918518B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333381C (en) 1986-02-20 1994-12-06 Eric D. Nyberg Method and articles employing ion exchange material
US5801186A (en) * 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
CA2157348A1 (en) * 1994-09-01 1996-03-02 Aventis Pharmaceuticals Inc. 3-¬4-(1-substituted-4-piperazinyl)butyl|-4-thiazolidinone and related compounds
CA2289574C (en) 1997-05-30 2007-04-24 Neurosearch A/S 8-azabicyclo(3,2,1)oct-2-ene and octane derivatives as cholinergic ligands at nicotinic ach receptors
KR100812499B1 (ko) * 2006-10-16 2008-03-11 이도훈 항경련제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2804460A (en) * 1955-07-15 1957-08-27 Irwin Neisler And Company Tropene derivatives
US3452029A (en) * 1966-11-21 1969-06-24 American Home Prod 3-alpha-phenylbenzyloxy - 8 - substituted nortropanes and their substitutents
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
ATE81123T1 (de) * 1987-11-20 1992-10-15 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.

Also Published As

Publication number Publication date
AU639195B2 (en) 1993-07-15
AU8606291A (en) 1992-04-30
HUT59401A (en) 1992-05-28
JPH04264085A (ja) 1992-09-18
BR9104632A (pt) 1992-06-09
HU913370D0 (en) 1992-01-28
GR3023441T3 (en) 1997-08-29
DE69125569T2 (de) 1997-09-18
YU168491A (sh) 1995-01-31
CA2054225A1 (en) 1992-04-27
IE913756A1 (en) 1992-05-22
PT99331A (pt) 1992-09-30
US5045546A (en) 1991-09-03
PT99331B (pt) 2000-08-31
DK0483633T3 (da) 1997-09-15
EP0483633B1 (en) 1997-04-09
FI915025A0 (fi) 1991-10-24
NO914192D0 (no) 1991-10-25
NO914192L (no) 1992-04-27
EP0483633A1 (en) 1992-05-06
DE69125569D1 (de) 1997-05-15
ES2099727T3 (es) 1997-06-01
ZA918518B (en) 1992-07-29
FI915025A (fi) 1992-04-27
JP2564719B2 (ja) 1996-12-18
ATE151422T1 (de) 1997-04-15

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