ZA918518B - 8-azabicyclo(3.2.1)octylalkylthiazolidinones,a process for their preparation and their use as medicaments - Google Patents

8-azabicyclo(3.2.1)octylalkylthiazolidinones,a process for their preparation and their use as medicaments

Info

Publication number
ZA918518B
ZA918518B ZA918518A ZA918518A ZA918518B ZA 918518 B ZA918518 B ZA 918518B ZA 918518 A ZA918518 A ZA 918518A ZA 918518 A ZA918518 A ZA 918518A ZA 918518 B ZA918518 B ZA 918518B
Authority
ZA
South Africa
Prior art keywords
octylalkylthiazolidinones
azabicyclo
medicaments
preparation
alkyl
Prior art date
Application number
ZA918518A
Other languages
English (en)
Inventor
Nicholas J Hrib
J Hrib Nicholas
John G Jurcak
G Jurcak John
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA918518B publication Critical patent/ZA918518B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA918518A 1990-10-26 1991-10-25 8-azabicyclo(3.2.1)octylalkylthiazolidinones,a process for their preparation and their use as medicaments ZA918518B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/603,491 US5045546A (en) 1990-10-26 1990-10-26 8-azabicyclo[3.2.1]octylalkylthiazolidines

Publications (1)

Publication Number Publication Date
ZA918518B true ZA918518B (en) 1992-07-29

Family

ID=24415671

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918518A ZA918518B (en) 1990-10-26 1991-10-25 8-azabicyclo(3.2.1)octylalkylthiazolidinones,a process for their preparation and their use as medicaments

Country Status (19)

Country Link
US (1) US5045546A (xx)
EP (1) EP0483633B1 (xx)
JP (1) JP2564719B2 (xx)
AT (1) ATE151422T1 (xx)
AU (1) AU639195B2 (xx)
BR (1) BR9104632A (xx)
CA (1) CA2054225A1 (xx)
CS (1) CS323091A3 (xx)
DE (1) DE69125569T2 (xx)
DK (1) DK0483633T3 (xx)
ES (1) ES2099727T3 (xx)
FI (1) FI915025A (xx)
GR (1) GR3023441T3 (xx)
HU (1) HUT59401A (xx)
IE (1) IE913756A1 (xx)
NO (1) NO914192L (xx)
PT (1) PT99331B (xx)
YU (1) YU168491A (xx)
ZA (1) ZA918518B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK87287A (da) 1986-02-20 1987-08-21 Raychem Corp Fremgangsmaade og apparat for anvendelse af ionbyttemateriale
US5801186A (en) 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
CA2157348A1 (en) * 1994-09-01 1996-03-02 Aventis Pharmaceuticals Inc. 3-¬4-(1-substituted-4-piperazinyl)butyl|-4-thiazolidinone and related compounds
ATE267199T1 (de) 1997-05-30 2004-06-15 Neurosearch As 8-azabicyclo(3,2,1)oct-2-en- und octanderivate als liganden der nicotinergen ach rezeptoren
KR100812499B1 (ko) * 2006-10-16 2008-03-11 이도훈 항경련제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2804460A (en) * 1955-07-15 1957-08-27 Irwin Neisler And Company Tropene derivatives
US3452029A (en) * 1966-11-21 1969-06-24 American Home Prod 3-alpha-phenylbenzyloxy - 8 - substituted nortropanes and their substitutents
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
EP0316723B1 (en) * 1987-11-20 1992-09-30 Hoechst-Roussel Pharmaceuticals Incorporated 3-[4(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinones a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
NO914192L (no) 1992-04-27
EP0483633A1 (en) 1992-05-06
ES2099727T3 (es) 1997-06-01
CA2054225A1 (en) 1992-04-27
EP0483633B1 (en) 1997-04-09
NO914192D0 (no) 1991-10-25
HU913370D0 (en) 1992-01-28
FI915025A0 (fi) 1991-10-24
IE913756A1 (en) 1992-05-22
JP2564719B2 (ja) 1996-12-18
CS323091A3 (en) 1992-05-13
JPH04264085A (ja) 1992-09-18
AU8606291A (en) 1992-04-30
PT99331B (pt) 2000-08-31
DE69125569T2 (de) 1997-09-18
FI915025A (fi) 1992-04-27
DE69125569D1 (de) 1997-05-15
AU639195B2 (en) 1993-07-15
HUT59401A (en) 1992-05-28
GR3023441T3 (en) 1997-08-29
DK0483633T3 (da) 1997-09-15
YU168491A (sh) 1995-01-31
BR9104632A (pt) 1992-06-09
PT99331A (pt) 1992-09-30
US5045546A (en) 1991-09-03
ATE151422T1 (de) 1997-04-15

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