CS275838B6 - Method for production of hybridoms used for monoclonal antigen against hiv virus producing - Google Patents

Method for production of hybridoms used for monoclonal antigen against hiv virus producing Download PDF

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Publication number
CS275838B6
CS275838B6 CS876136A CS613687A CS275838B6 CS 275838 B6 CS275838 B6 CS 275838B6 CS 876136 A CS876136 A CS 876136A CS 613687 A CS613687 A CS 613687A CS 275838 B6 CS275838 B6 CS 275838B6
Authority
CS
Czechoslovakia
Prior art keywords
hiv
antibodies
peptide
peptides
virus
Prior art date
Application number
CS876136A
Other languages
Czech (cs)
English (en)
Other versions
CS8706136A2 (en
Inventor
Kathleen Mary Shriver
Elaine K Thomas
Wesley L Cosand
Larry H Gosting
Edna S Dickinson
Janela Mcclure
George J Todaro
Robert C Nowinski
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of CS8706136A2 publication Critical patent/CS8706136A2/cs
Publication of CS275838B6 publication Critical patent/CS275838B6/cs

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00Multi-stage pumps
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • AIDS & HIV (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CS876136A 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing CS275838B6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (2)

Publication Number Publication Date
CS8706136A2 CS8706136A2 (en) 1990-08-14
CS275838B6 true CS275838B6 (en) 1992-03-18

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
CS876136A CS275838B6 (en) 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing

Country Status (28)

Country Link
JP (1) JPS6485928A (de)
KR (1) KR920008744B1 (de)
AT (1) AT398080B (de)
AU (1) AU616156B2 (de)
BE (1) BE1000811A4 (de)
CH (1) CH675728A5 (de)
CS (1) CS275838B6 (de)
DE (1) DE3727703A1 (de)
DK (1) DK433087A (de)
ES (1) ES2010727A6 (de)
FI (1) FI873553A (de)
FR (1) FR2603107B1 (de)
GB (1) GB2196634B (de)
GR (1) GR871298B (de)
HU (1) HU214439B (de)
IE (1) IE60671B1 (de)
IL (1) IL83580A (de)
IT (1) IT1222518B (de)
LU (1) LU86972A1 (de)
NL (1) NL8701950A (de)
NO (2) NO300462B1 (de)
NZ (1) NZ221440A (de)
OA (1) OA08652A (de)
PL (1) PL155084B1 (de)
PT (1) PT85567B (de)
SE (1) SE506025C2 (de)
YU (1) YU152587A (de)
ZW (1) ZW15487A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
JP2520464B2 (ja) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Hiv―1を中和するモノクロ―ナル抗体
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
WO1989007112A1 (en) * 1988-01-26 1989-08-10 The United States Of America, As Represented By Th A synthetic antigen evoking anti-hiv response
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (de) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Menschliches immunoinsuffizientes Virus (HIV) env-codiertes Peptid, welches im Stande ist, die HIV hemmenden Antikörper bei Säugetieren hervorzurufen
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
AU640619B2 (en) * 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
EP0421626A1 (de) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vakzin gegen AIDS und Hepatitis B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv関連環状ペプチドおよびこれを固定化した吸着体
ES2222625T3 (es) * 1992-03-27 2005-02-01 Advanced Immuni T, Inc. Peptido t y peptidos asociados destinados al tratamiento de la inflamacion incluyendo la esclerosis multiple.
PT1976548E (pt) 2005-12-09 2014-10-13 Vectus Biosystems Ltd Fragmentos de vip e suas composições
WO2010026940A1 (ja) 2008-09-02 2010-03-11 日本特殊陶業株式会社 スパークプラグ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
EP0201540B2 (de) * 1984-10-18 2001-10-31 Institut Pasteur Lymphadenopathie-assoziierte hüllenantigene und deren verwendungen
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
CA1341482C (en) * 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
GR860915B (en) * 1985-04-08 1986-07-11 Genetic Systems Corp Expression and diagnostic use of gag encoded peptides which are immunologically reactive with antibodies to lav
DK171119B1 (da) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
DE3650175T3 (de) * 1985-04-29 2007-09-06 Bio-Rad Laboratories, Inc., Hercules Synthetische antigene zum nachweis von aids.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
ATE108022T1 (de) * 1985-10-24 1994-07-15 Southwest Found Biomed Res Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
DE3787002T2 (de) * 1986-12-30 1993-11-25 Us Health Synthetische Peptide, die zelluläre Immunität gegen den AIDS-Virus und dessen Proteine erzeugen.

Also Published As

Publication number Publication date
IE872219L (en) 1988-02-20
FI873553A0 (fi) 1987-08-17
HU214439B (hu) 1998-03-30
NO873495L (no) 1988-02-22
SE506025C2 (sv) 1997-11-03
IT8721678A0 (it) 1987-08-19
IT1222518B (it) 1990-09-05
SE8703225D0 (sv) 1987-08-19
CS8706136A2 (en) 1990-08-14
PL155084B1 (en) 1991-10-31
NO934897D0 (no) 1993-12-29
FR2603107B1 (fr) 1992-04-24
PT85567A (en) 1987-09-01
PT85567B (pt) 1991-02-08
ATA208987A (de) 1994-01-15
NO873495D0 (no) 1987-08-19
NO300462B1 (no) 1997-06-02
AT398080B (de) 1994-09-26
NO934897L (no) 1993-12-29
AU7720187A (en) 1988-05-19
YU152587A (sh) 1992-09-07
IE60671B1 (en) 1994-08-10
NZ221440A (en) 1991-11-26
PL267401A1 (en) 1988-07-21
KR890002547A (ko) 1989-04-10
DK433087D0 (da) 1987-08-19
SE8703225L (sv) 1988-02-21
HUT44619A (en) 1988-03-28
GR871298B (en) 1988-01-12
ES2010727A6 (es) 1989-12-01
OA08652A (fr) 1988-11-30
FR2603107A1 (fr) 1988-02-26
GB2196634B (en) 1991-05-15
DE3727703A1 (de) 1988-05-05
AU616156B2 (en) 1991-10-24
LU86972A1 (fr) 1988-03-02
NL8701950A (nl) 1988-03-16
GB8719587D0 (en) 1987-09-23
DK433087A (da) 1988-02-21
KR920008744B1 (ko) 1992-10-09
FI873553A (fi) 1988-02-21
IL83580A (en) 1992-11-15
JPS6485928A (en) 1989-03-30
GB2196634A (en) 1988-05-05
ZW15487A1 (en) 1988-09-14
CH675728A5 (de) 1990-10-31
BE1000811A4 (fr) 1989-04-11
IL83580A0 (en) 1988-01-31
NO302176B1 (no) 1998-02-02

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