CS271486B2 - Method of new dihydropyridinamides production - Google Patents

Method of new dihydropyridinamides production Download PDF

Info

Publication number
CS271486B2
CS271486B2 CS882354A CS235488A CS271486B2 CS 271486 B2 CS271486 B2 CS 271486B2 CS 882354 A CS882354 A CS 882354A CS 235488 A CS235488 A CS 235488A CS 271486 B2 CS271486 B2 CS 271486B2
Authority
CS
Czechoslovakia
Prior art keywords
group
phenyl
dihydro
dicarboxylic acid
carbon atoms
Prior art date
Application number
CS882354A
Other languages
Czech (cs)
English (en)
Other versions
CS235488A2 (en
Inventor
Jurgen Ing Stoltefuss
Eckhard Dr Schwenner
Martin Dr Bechem
Claudia Dr Hirth
Michael Dr Kayser
Matthias Dr Schramm
Johannes-Peter Dr Stasch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Priority to CS892249A priority Critical patent/CS271494B2/cs
Priority to CS892254A priority patent/CS271499B2/cs
Priority to CS892252A priority patent/CS271497B2/cs
Priority to CS892253A priority patent/CS271498B2/cs
Priority to CS892250A priority patent/CS271495B2/cs
Priority to CS892251A priority patent/CS271496B2/cs
Priority to CS892255A priority patent/CS271500B2/cs
Publication of CS235488A2 publication Critical patent/CS235488A2/cs
Publication of CS271486B2 publication Critical patent/CS271486B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS882354A 1987-04-09 1988-04-06 Method of new dihydropyridinamides production CS271486B2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CS892249A CS271494B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892254A CS271499B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892252A CS271497B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892253A CS271498B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892250A CS271495B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892251A CS271496B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production
CS892255A CS271500B2 (en) 1987-04-09 1989-04-12 Method of new dihydropyridinamides production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873711991 DE3711991A1 (de) 1987-04-09 1987-04-09 Dihydropyridinamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
CS235488A2 CS235488A2 (en) 1990-02-12
CS271486B2 true CS271486B2 (en) 1990-10-12

Family

ID=6325224

Family Applications (1)

Application Number Title Priority Date Filing Date
CS882354A CS271486B2 (en) 1987-04-09 1988-04-06 Method of new dihydropyridinamides production

Country Status (20)

Country Link
EP (1) EP0288758B1 (ja)
JP (1) JPS6419066A (ja)
KR (1) KR880012553A (ja)
CN (1) CN88101927A (ja)
AT (1) ATE66209T1 (ja)
AU (1) AU602970B2 (ja)
CA (1) CA1328869C (ja)
CS (1) CS271486B2 (ja)
DD (1) DD274026A5 (ja)
DE (2) DE3711991A1 (ja)
DK (1) DK192988A (ja)
ES (1) ES2039267T3 (ja)
FI (1) FI881609A (ja)
GR (1) GR3002679T3 (ja)
HU (1) HU204786B (ja)
IL (1) IL85992A0 (ja)
NO (1) NO881308L (ja)
NZ (1) NZ224125A (ja)
PT (1) PT87182B (ja)
ZA (1) ZA882449B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833892A1 (de) * 1988-10-05 1990-04-12 Bayer Ag Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5124508A (en) * 1990-08-14 1992-06-23 The Scabbard Corp. Application of sheet batteries as support base for electronic circuits
US5147985A (en) * 1990-08-14 1992-09-15 The Scabbard Corporation Sheet batteries as substrate for electronic circuit
DE4100125A1 (de) * 1991-01-04 1992-07-09 Bayer Ag Neue dihydropyridinamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
GB9100932D0 (en) * 1991-01-16 1991-02-27 Tomlin Trevor V Frames
DE4118707A1 (de) * 1991-06-07 1992-12-10 Bayer Ag Pharmazeutische verwendung von 3-formyl-1,4-dihydropyridinen, neue verbindungen und verfahren zu ihrer herstellung
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy
DE4134760A1 (de) * 1991-10-22 1993-07-08 Bayer Ag Aryl-chinolyl-substituierte 1,4-dihydropyridin-dicarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JP2007230869A (ja) * 2004-04-05 2007-09-13 Takeda Chem Ind Ltd アルドステロン受容体拮抗剤
WO2010015652A2 (en) * 2008-08-07 2010-02-11 Smithkline Beecham Corporation Thiazole compounds as activators of soluble guanylate cyclase
JP2014503000A (ja) * 2011-01-21 2014-02-06 アッヴィ・インコーポレイテッド キナーゼのピコリンアミド阻害剤
CN115403519B (zh) * 2022-08-31 2024-03-01 河南师范大学 一种可见光驱动的n-取代异烟酰胺类化合物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2228377A1 (de) * 1972-06-10 1974-01-03 Bayer Ag Dihydropyridin-carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2508446B1 (fr) * 1981-06-25 1986-05-02 Rhone Poulenc Agrochimie Herbicides a fonctions amide et ester derives de la pyridine ainsi que leur procede de preparation et leur application
EP0111453A1 (de) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Amid-Verbindungen
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity

Also Published As

Publication number Publication date
HU204786B (en) 1992-02-28
NZ224125A (en) 1990-11-27
NO881308D0 (no) 1988-03-24
AU602970B2 (en) 1990-11-01
IL85992A0 (en) 1988-09-30
CN88101927A (zh) 1988-11-16
JPS6419066A (en) 1989-01-23
ZA882449B (en) 1988-09-29
HUT46664A (en) 1988-11-28
EP0288758A2 (de) 1988-11-02
DE3711991A1 (de) 1988-10-20
EP0288758A3 (en) 1989-03-01
DE3864177D1 (de) 1991-09-19
FI881609A0 (fi) 1988-04-07
ES2039267T3 (es) 1993-09-16
CS235488A2 (en) 1990-02-12
FI881609A (fi) 1988-10-10
ATE66209T1 (de) 1991-08-15
EP0288758B1 (de) 1991-08-14
DK192988D0 (da) 1988-04-08
DD274026A5 (de) 1989-12-06
GR3002679T3 (en) 1993-01-25
NO881308L (no) 1988-10-10
PT87182B (pt) 1995-01-31
DK192988A (da) 1988-10-10
CA1328869C (en) 1994-04-26
AU1413788A (en) 1988-10-13
KR880012553A (ko) 1988-11-28
PT87182A (pt) 1989-05-12

Similar Documents

Publication Publication Date Title
DK170891B1 (da) 1,4-dihydropyridin-3,5-dicarboxylsyrederivater og fremgangsmåde til fremstilling deraf samt farmaceutisk middel indeholdende dem
US4448964A (en) 1,4-Dihydropyridine derivatives
DK164158B (da) 1,4-dihydropyridincarboxylsyreestere
US5670525A (en) Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders
US4994461A (en) 1,4-dihydropyridine enantiomers
CS271486B2 (en) Method of new dihydropyridinamides production
US4640922A (en) 3N-substituted 3,4-dihydropyrimidines as agents for treating disorders of cardiovascular system
US6121284A (en) 2,3-bridged 1,4-dihydropyridines, and their use as medicaments
CA1267416A (en) 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US5015650A (en) Circulation-active basic 4-aryl-DHP amides
EP0161917B1 (en) Dihydropyridines
EP0257616A2 (en) Dihydropyridine derivates and pharmaceutical composition thereof
IE922512A1 (en) Novel n-alkylated 1,4-dihydropyridinedicarboxylic acid¹esters
NO854021L (no) 1,4-dihydropyridin-hydroksyaminer og fremgangsmaate til fremstilling derav.
US4886819A (en) Dihydropyridine derivatives and pharmaceutical composition thereof
CS271494B2 (en) Method of new dihydropyridinamides production
US5403849A (en) 4-heterocyclophenyl-substituted dihydropyridines
JP3959127B2 (ja) フエニル−置換１，４−ジヒドロピリジン類
KR20000075642A (ko) 세로토닌-2 수용체 길항작용 및 알파 1-저해 작용을 갖는 피롤로티아진 및 피롤로티아제핀 화합물
EP0221720B1 (en) Dihydropyridines
US4675329A (en) Isopropyl 2-(3-trifluoromethylphenoxy)-ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate as vaso-dilators
CZ227693A3 (en) 4-heterocyclyl substituted dihydropyridines, process of their preparation and medicaments in which they are comprised
KR950002154B1 (ko) 2-(아미노알킬티오)메틸-1,4-디히드로피리딘의 제조방법
JPH09510964A (ja) 抗高血圧剤としての４−（２−（３−アリールオキシ−２−ヒドロキシプロピルアミノアルキルオキシ）−５−ニトロフェニル）−１，４−ジヒドロピリジン
JPH0859654A (ja) 中枢神経系治療用薬剤としての６−アミノ−１，４−ジヒドロピリジン類の使用およびそれらの製造方法