CS265238B2 - Method of injection applicable water solutions antimetic agent stabilization - Google Patents

Method of injection applicable water solutions antimetic agent stabilization Download PDF

Info

Publication number
CS265238B2
CS265238B2 CS872472A CS247287A CS265238B2 CS 265238 B2 CS265238 B2 CS 265238B2 CS 872472 A CS872472 A CS 872472A CS 247287 A CS247287 A CS 247287A CS 265238 B2 CS265238 B2 CS 265238B2
Authority
CS
Czechoslovakia
Prior art keywords
water
glycerol
compound
pharmaceutically acceptable
ethanol
Prior art date
Application number
CS872472A
Other languages
Czech (cs)
English (en)
Other versions
CS247287A2 (en
Inventor
Munir N Nassar
Shreeram N Agharkar
Joseph B Bogardus
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/019,733 external-priority patent/US4882356A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CS247287A2 publication Critical patent/CS247287A2/cs
Publication of CS265238B2 publication Critical patent/CS265238B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS872472A 1986-04-07 1987-04-06 Method of injection applicable water solutions antimetic agent stabilization CS265238B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84861586A 1986-04-07 1986-04-07
US07/019,733 US4882356A (en) 1987-03-10 1987-03-10 Stable injectable antiemetic compositions

Publications (2)

Publication Number Publication Date
CS247287A2 CS247287A2 (en) 1989-01-12
CS265238B2 true CS265238B2 (en) 1989-10-13

Family

ID=26692535

Family Applications (1)

Application Number Title Priority Date Filing Date
CS872472A CS265238B2 (en) 1986-04-07 1987-04-06 Method of injection applicable water solutions antimetic agent stabilization

Country Status (19)

Country Link
EP (1) EP0241837B1 (da)
KR (1) KR900002745B1 (da)
CN (1) CN87103415A (da)
AT (1) ATE70716T1 (da)
AU (1) AU597955B2 (da)
CA (1) CA1282703C (da)
CS (1) CS265238B2 (da)
DE (1) DE3775445D1 (da)
DK (1) DK175787A (da)
EG (1) EG18407A (da)
ES (1) ES2038134T3 (da)
FI (1) FI871447A (da)
GR (1) GR3003636T3 (da)
HU (1) HU198622B (da)
IL (1) IL82122A0 (da)
NO (1) NO871434L (da)
NZ (1) NZ219890A (da)
PT (1) PT84635B (da)
ZW (1) ZW6287A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561161A (en) * 1994-03-25 1996-10-01 Oxigene, Inc. Methods of administering and pharmaceutical formulations containing n-substituted benzamides and/or acid addition salts thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2731013C2 (de) * 1977-07-08 1982-07-15 Lentia Gmbh Verfahren zur Herstellung einer wäßrigen Infusionslösung
EP0008525A3 (en) * 1978-08-25 1980-05-28 Beecham Group Plc Pharmaceutical compositions and process for their preparation
JPS599539B2 (ja) * 1979-11-13 1984-03-03 日本化薬株式会社 ニトログリセリン水溶液及びその製造法
US4328213A (en) * 1979-11-28 1982-05-04 Schering Corporation Stable injectable labetalol formulation
GB8412585D0 (en) * 1984-05-17 1984-06-20 Beecham Group Plc Composition
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
AU5063885A (en) * 1984-10-23 1986-05-15 Nastech Pharmaceutical Co., Inc. Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same

Also Published As

Publication number Publication date
FI871447A (fi) 1987-10-08
DK175787D0 (da) 1987-04-06
ATE70716T1 (de) 1992-01-15
NO871434L (no) 1987-10-08
DK175787A (da) 1987-10-08
KR900002745B1 (ko) 1990-04-28
HU198622B (en) 1989-11-28
AU597955B2 (en) 1990-06-14
NO871434D0 (no) 1987-04-06
CA1282703C (en) 1991-04-09
EG18407A (en) 1993-02-28
IL82122A0 (en) 1987-10-30
GR3003636T3 (da) 1993-03-16
FI871447A0 (fi) 1987-04-02
KR870009714A (ko) 1987-11-30
CS247287A2 (en) 1989-01-12
ES2038134T3 (es) 1993-07-16
PT84635B (pt) 1989-11-30
EP0241837A2 (en) 1987-10-21
NZ219890A (en) 1990-07-26
CN87103415A (zh) 1988-01-20
HUT43489A (en) 1987-11-30
DE3775445D1 (de) 1992-02-06
PT84635A (en) 1987-05-01
EP0241837B1 (en) 1991-12-27
AU7115987A (en) 1987-10-08
EP0241837A3 (en) 1989-05-10
ZW6287A1 (en) 1987-09-23

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