ES2038134T3 - Composiciones antiemeticas inyectables estables. - Google Patents

Composiciones antiemeticas inyectables estables.

Info

Publication number
ES2038134T3
ES2038134T3 ES198787105073T ES87105073T ES2038134T3 ES 2038134 T3 ES2038134 T3 ES 2038134T3 ES 198787105073 T ES198787105073 T ES 198787105073T ES 87105073 T ES87105073 T ES 87105073T ES 2038134 T3 ES2038134 T3 ES 2038134T3
Authority
ES
Spain
Prior art keywords
stable injectable
water
injectable
stable
antiemetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787105073T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/019,733 external-priority patent/US4882356A/en
Application filed filed Critical
Application granted granted Critical
Publication of ES2038134T3 publication Critical patent/ES2038134T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A SOLUCIONES ACUOSAS ESTABLES, INYECTABLES, DE AGENTES ANTIEMETICOS A BASE DE 4 - AMINO - 5 - CLORO - N - [2- (DIETILAMINO) ETIL] -2-(ALCOXISUSTITUIDO)BENZAMIDA, QUE SE PREPARAN POR ADICION DE UN ESTABILIZANTE, FARMACEUTICAMENTE ACEPTABLE, MISCIBLE CON AGUA, UN DISOLVENTE ORGANICO HIDROXILADO O UN ALCOHOL POLIHIDRICO O UN AZUCAR SOLUBLES EN AGUA QUE DISMINUYEN LA POLARIDAD DE LA SOLUCION.
ES198787105073T 1986-04-07 1987-04-06 Composiciones antiemeticas inyectables estables. Expired - Lifetime ES2038134T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84861586A 1986-04-07 1986-04-07
US07/019,733 US4882356A (en) 1987-03-10 1987-03-10 Stable injectable antiemetic compositions

Publications (1)

Publication Number Publication Date
ES2038134T3 true ES2038134T3 (es) 1993-07-16

Family

ID=26692535

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787105073T Expired - Lifetime ES2038134T3 (es) 1986-04-07 1987-04-06 Composiciones antiemeticas inyectables estables.

Country Status (19)

Country Link
EP (1) EP0241837B1 (es)
KR (1) KR900002745B1 (es)
CN (1) CN87103415A (es)
AT (1) ATE70716T1 (es)
AU (1) AU597955B2 (es)
CA (1) CA1282703C (es)
CS (1) CS265238B2 (es)
DE (1) DE3775445D1 (es)
DK (1) DK175787A (es)
EG (1) EG18407A (es)
ES (1) ES2038134T3 (es)
FI (1) FI871447A (es)
GR (1) GR3003636T3 (es)
HU (1) HU198622B (es)
IL (1) IL82122A0 (es)
NO (1) NO871434L (es)
NZ (1) NZ219890A (es)
PT (1) PT84635B (es)
ZW (1) ZW6287A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561161A (en) * 1994-03-25 1996-10-01 Oxigene, Inc. Methods of administering and pharmaceutical formulations containing n-substituted benzamides and/or acid addition salts thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2731013C2 (de) * 1977-07-08 1982-07-15 Lentia Gmbh Verfahren zur Herstellung einer wäßrigen Infusionslösung
EP0008525A3 (en) * 1978-08-25 1980-05-28 Beecham Group Plc Pharmaceutical compositions and process for their preparation
JPS599539B2 (ja) * 1979-11-13 1984-03-03 日本化薬株式会社 ニトログリセリン水溶液及びその製造法
US4328213A (en) * 1979-11-28 1982-05-04 Schering Corporation Stable injectable labetalol formulation
GB8412585D0 (en) * 1984-05-17 1984-06-20 Beecham Group Plc Composition
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
WO1986002553A1 (en) * 1984-10-23 1986-05-09 Nastech Pharmaceutical Company, Inc. Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same

Also Published As

Publication number Publication date
PT84635A (en) 1987-05-01
GR3003636T3 (es) 1993-03-16
DK175787D0 (da) 1987-04-06
DK175787A (da) 1987-10-08
DE3775445D1 (de) 1992-02-06
CS265238B2 (en) 1989-10-13
NO871434L (no) 1987-10-08
CN87103415A (zh) 1988-01-20
EP0241837A2 (en) 1987-10-21
FI871447A0 (fi) 1987-04-02
CS247287A2 (en) 1989-01-12
ATE70716T1 (de) 1992-01-15
EP0241837A3 (en) 1989-05-10
HUT43489A (en) 1987-11-30
EP0241837B1 (en) 1991-12-27
ZW6287A1 (en) 1987-09-23
NZ219890A (en) 1990-07-26
KR900002745B1 (ko) 1990-04-28
HU198622B (en) 1989-11-28
CA1282703C (en) 1991-04-09
FI871447A (fi) 1987-10-08
AU597955B2 (en) 1990-06-14
NO871434D0 (no) 1987-04-06
PT84635B (pt) 1989-11-30
AU7115987A (en) 1987-10-08
EG18407A (en) 1993-02-28
IL82122A0 (en) 1987-10-30
KR870009714A (ko) 1987-11-30

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